NR ALKE
AU Tange,R.A.; Troost,D.; Limburg,M.
TI Progressive fatal dementia (Creutzfeldt-Jakob disease) in a patient who received homograft tissue for tympanic membrane closure
QU European Archives of Oto-Rhino-Laryngology 1990; 247(4): 199-201
PT journal article
AB We report the case history of a 54-year-old man who developed a fatal neurological disorder 4 years after a successful tympanoplasty with homograft pericardium. The final diagnosis of this case was Creutzfeldt-Jakob disease. This infectious spongiform encephalopathy is probably caused by a slow virus that can be transmitted by transplantation materials. The possible accidental transmission of Creutzfeldt-Jakob disease by the use of homograft materials in otologic surgery is discussed.
MH Case Report; Cerebral Cortex/pathology; Cialit; Creutzfeldt-Jakob Syndrome/pathology/*transmission; Human; Male; Middle Age; Pericardium/*transplantation; Time Factors; Tissue Preservation; Transplantation, Homologous; *Tympanoplasty
AD Department of Otolaryngology, University of Amsterdam, The Netherlands.
SP englisch
PO Westdeutschland