NR ALNZ
AU Taylor,D.M.
TI Resistance of the ME7 scrapie agent to peracetic acid
QU Veterinary Microbiology 1991 Mar; 27(1): 19-24
PT journal article
AB Mouse brain infected with the ME7 strain of scrapie agent was exposed for 24 h to a range of concentrations of PAA, either as fragments of intact brain or as supernates of homogenised brain. Two % PAA inactivated the infectivity in intact tissue but not in a supernate. None of the concentrations tested (up to 19%) was effective with supernates, and this was considered to result from the protection afforded by aggregation of infectivity-containing particles.
MH Animal; Brain/*microbiology; Drug Resistance, Microbial; Mice; Mice, Inbred C57BL; Peracetic Acid/*pharmacology; Prions/*drug effects
AD AFRC & MRC Neuropathogenesis Unit, Institute for Animal Health, Edinburgh, UK
SP englisch
PO Niederlande