NR ALYI

AU van Gool,W.A.; Meijerink,P.H.

TI [Creutzfeldt-Jakob disease; one year later]

OT De ziekte van Creutzfeldt-Jakob; een jaar later.

QU Nederlands Tijdschrift voor Geneeskunde 1997 Mar 29; 141(13): 613-5

PT journal article; review; review, tutorial

AB During the last year the knowledge of the transmission of prion diseases has increased. New diagnostic methods were developed: investigation of cerebrospinal fluid for the 14-3-3 protein and tonsillar biopsy to detect protease resistant prion protein. Indirect evidence of a causal relation between new variant Creutzfeldt-Jakob disease (nvCJ) and bovine spongiform encephalopathy (BSE) is accumulating, although epidemiological data do not indicate that the incidence of CJ is increasing.

ZR 20

MH Adult; Animal; Cattle; Cattle Diseases/transmission; Creutzfeldt-Jakob Syndrome/cerebrospinal fluid/*epidemiology/transmission; Disease Outbreaks; Encephalopathy, Bovine Spongiform/transmission; English Abstract; Great Britain/epidemiology; Human; Middle Age; Netherlands/epidemiology; Prions/cerebrospinal fluid

AD Academisch Medisch Centrum, afd. Neurologie, Amsterdam.

SP niederländisch

PO Niederlande

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