NR ALZD
AU Vanmechelen,E.; Vanderstichele,H.; Hulstaert,F.; Andreasen,N.; Minthon,L.; Winblad,B.; Davidsson,P.; Blennow,K.
TI Cerebrospinal fluid tau and beta-amyloid(1-42) in dementia disorders
QU Mechanisms of Ageing and Development 2001 Nov; 122(16): 2005-11
PT journal article; review; review, tutorial
AB The reliability of cerebrospinal fluid (CSF)-tau and CSF-beta-amyloid assays for diagnosis of Alzheimer's disease and other dementing disorders such as frontotemporal dementia (FTD), dementia with Lewy bodies (DLB) and Creutzfeldt-Jakob disease (CJD) is reviewed. CSF assessment of the two proteins is useful in early diagnosis of AD and to differentiate it from FTD and DLB. Extremely high CSF-tau levels can discriminate CJD from AD.
ZR 36
MH Amyloid beta-Protein/*cerebrospinal fluid; Dementia/*cerebrospinal fluid/diagnosis; Human; Peptide Fragments/*cerebrospinal fluid; Time Factors; tau Proteins/*cerebrospinal fluid
AD Innogenetics NV, Industriepark Zwijnaarde 7, Box 4, B-9052, Ghent, Belgium. eugeevme@innogenetics.com
SP englisch
PO Irland