NR AMAI

AU Vettermann,W.; Werner,H.J.; Schmeisser,S.; Koch,M.A.

TI Observation on the capping of spleen lymphocytes from scrapie infected mice after treatment with anti Ig

QU Medical Microbiology and Immunology. Zeitschrift für medizinische Mikrobiologie und Immunologie 1981; 169(2): 75-81

PT journal article

AB Staining of lymphocytes from scrapie-infected STU mice with FITC-labelled anti-mouse Ig revealed disturbances in the capping process when compared with lymphocytes from mock-infected animals. Quantitative evaluation indicates that 10-15% of cells from scrapie-infected animals show an altered capping behaviour. These phenomena are discussed with special reference to the role of the lymphoreticular system in early scrapie agent replication.

MH Animal; Antibodies, Anti-Idiotypic/*immunology; Female; *Immunologic Capping; Lymphocytes/*immunology; Mice; Scrapie/*immunology; Sheep; Spleen/cytology; Staining and Labeling

SP englisch

PO Westdeutschland

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