NR AMUL
AU Yamamoto,T.; Yamashita,M.
TI Thalamo-olivary degeneration in a patient with laryngopharyngeal dystonia
QU Journal of Neurology, Neurosurgery and Psychiatry 1995 Oct; 59(4): 438-41
PT journal article
AB A 67 year old woman with a two year history of laryngopharyngeal dystonia, spasmodic dysphonia, and parkinsonism succumbed to Wernicke's encephalopathy and died six months later. Necropsy showed, besides Wernicke's encephalopathy, degenerative changes in selected thalamic nuclei (dorsomedial, pulvinar, and the medial geniculate bodies) and the inferior olives and numerous cerebellar torpedoes. The substantia nigra and basal ganglia were spared. Immunostaining for prion protein was negative. This patient indicated a new type of presentation of so-called pure thalamic degeneration, or more precisely thalamo-olivary degeneration.
MH Aged; Case Report; Dystonia/*pathology; Female; Human; Laryngeal Diseases/*pathology; Muscle Spasticity/pathology; *Nerve Degeneration; Olivary Nucleus/pathology; Parkinson Disease/pathology; Pharyngeal Diseases/*pathology; Thalamic Diseases/*pathology; Thalamus/pathology; Voice Disorders/pathology; Wernicke Encephalopathy/pathology
AD Department of Neurology, Osaka Saiseikai Nakatsu Hospital, Japan.
SP englisch
PO England