NR ANAS
AU Zochodne,D.W.; Young,G.B.; McLachlan,R.S.; Gilbert,J.J.; Vinters,H.V.; Kaufmann,J.C.E.
TI Creutzfeldt-Jakob disease without periodic sharp wave complexes: a clinical, electroencephalographic, and pathologic study.
QU Neurology 1988 Jul; 38(7): 1056-60
PT journal article
AB A comparison of clinical, EEG, and pathologic features was carried out on all cases of autopsy-proven Creutzfeldt-Jakob disease (CJD) studied over the last 10 years. Periodic sharp wave complexes (PSWCs) were present in three but absent in seven patients. Myoclonus was documented in two of the three with and in only one of the seven without PSWCs. The three with PSWCs had severe neocortical and at least mild thalamic involvement; those without PSWCs had more variable disease topography. The diagnosis of CJD should not be rejected if PSWCs are absent.
MH Aged; Aphasia/physiopathology; Brain/pathology/*physiopathology; Creutzfeldt-Jakob Syndrome/pathology/*physiopathology; Dementia/physiopathology; Electroencephalography; Female; Human; Male; Middle Age; Myoclonus/physiopathology; Support, Non-U.S. Gov't
AD Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada.
SP englisch
PO USA