NR AOBP
AU Martindale,J.; Geschwind,M.D.; DeArmond,S.J.; Young,G.; Dillon,W.P.; Henry,R.; Uyehara-Lock,J.H.; Gaskin,D.A.; Miller,B.L.
TI Sporadic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease
QU Archives of Neurology 2003 May; 60(5): 767-70
PT journal article
AB BACKGROUND: The determination of the form of prion disease and early diagnosis are important for prognostic, public health, and epidemiologic reasons. OBJECTIVE: To describe a patient with sporadic Creutzfeldt-Jakob disease (sCJD) who had a clinical history and initial electroencephalogram and magnetic resonance imaging findings consistent with variant CJD (vCJD). RESULTS: Results of a repeated electroencephalogram were suggestive of sCJD, and a subsequent brain biopsy confirmed this diagnosis. CONCLUSIONS: This case cautions against relying solely on T2- and diffusion-weighted pulvinar hyperintensity and clinical features to differentiate between vCJD and sCJD, and further supports established diagnostic criteria for vCJD.
MH Adult; Biopsy; Brain/pathology; Case Report; Creutzfeldt-Jakob Syndrome/classification/*pathology; Diagnosis, Differential; Electroencephalography; Female; Human; *Magnetic Resonance Imaging; Pulvinar/pathology
AD Jennifer Martindale, Michael D. Geschwind (mgeschwind@memory.ucsf.edu), Bruce L. Miller, Department of Neurology, University of California-San Francisco, 94143, USA; Geoffrey Young, W. P. Dillon, Roland Henry, Department of Radiology, University of California-San Francisco, 94143, USA; Stehen J. DeArmond, Jane H. Uyehara-Lock, David A. Gaskin, Department of Pathology, University of California-San Francisco, 94143, USA
SP englisch
PO USA