NR AOGE
AU Horsfield,M.A.; Jones,D.K.
TI Applications of diffusion-weighted and diffusion tensor MRI to white matter diseases - a review
QU NMR in Biomedicine 2002 Nov-Dec; 15(7-8): 570-7
PT journal article; review; review, tutorial
AB This paper reviews the current applications of diffusion-weighted and diffusion tensor MRI in diseases of the brain white matter. The contribution that diffusion-weighted imaging has made to our understanding of white matter diseases is critically appraised. The quantitative nature of diffusion MRI is one of its major attractions; however, this is offset by the more advanced hardware required to collect diffusion-weighted images reliably, and the more complex processing to produce quantitative parametric diffusion images. With the now common availability of scanners equipped to perform echo-planar imaging, the acquisition of diffusion tensor images is sure to become more widespread and routine.
ZR 45
MH Alzheimer Disease/metabolism/pathology; Amyotrophic Lateral Sclerosis/metabolism/pathology; Anisotropy; Brain/metabolism/pathology; Creutzfeldt-Jakob Syndrome/metabolism/pathology; Dementia, Multi-Infarct/metabolism/pathology; Demyelinating Diseases/*metabolism/*pathology; Diffusion; Diffusion Magnetic Resonance Imaging/*methods; HIV Infections/metabolism/pathology; Multiple Sclerosis/metabolism/pathology; Neural Pathways/*metabolism/*pathology; Support, Non-U.S. Gov't; Water/metabolism
AD Division of Medical Physics, University of Leicester, Leicester Royal Infirmary, UK. mah5@le.ac.uk
SP englisch
PO England