NR AOTK
AU Göbel,S.B.; Staubach,C.; Selhorst,T.; Kramer,M.
TI Epidemiological BSE Situation in Germany and Regional BSE Incidences after Indirect age Standardization using Data of the Centralized Cattle Data Base 'HI-TIER'
QU International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-84
PT Konferenz-Poster
AB Since the beginning of the active surveillance of BSE, more than 6.9 million cattle were examined in Germany and 7 of them in the year 2000, 125 cattle in the year 2001, 106 cattle in the year 2002 and so far 13 cattle in the year 2003 (at 30-06-03) have shown a positive test result. The spatial distribution shows two distinct clusters in the south and north of Germany, whereas the rest of cases essentially follow the distribution of the cattle population. The weekly confirmation shows fluctuations between 0 and 9 cases per week and averages in the year 2001 2.4 cases per week, whereas in the year 2002 averagely 2.0 cases per week came to confirmation. The monthly confirmation also shows fluctuations between 1 and 19 cases per month, which can not be assigned to a seasonal course. Nearly 80 % of the BSE animals originate from the birth years 1995 and 1996. The oldest positive cow was born in 1987, so that it could be assumed, that BSE infections took place in the middle 80ties. The median age at death in the year 2001 was 64 months, and rose to 76 months in 2002 (all cases included: minimum 28 months, maximum 183 months). In case of BSE, the question of the regional (and also supraregional, e.g. breed, sex) exposition is often raised, which presupposes that the stratified data are comparable. A substantial factor of differences in the presence of a disease could be the heterogeneous age structure of the cattle in the different regions. Since autumn 1999, all cattle in German livestock population are registered in the centralized cattle data base 'Hi-Tier'. The selective inquiry of detailed population and death data from 'Hi-Tier' is a new possibility in epidemiological research in Germany. In this investigation the data will be standardized regarding to the age distribution of the cattle in different German areas (and other strata, e.g. breed). Methods of indirect age standardization, e.g. standardized mortality ratio (SMR) are suitable for our purpose.
AD S.B. Göbel, C. Staubach, T. Selhorst, M. Kramer, Federal Research Centre for Virus Diseases of Animals, Germany
SP englisch
PO Deutschland