NR AOUT
AU Klass,M.; Hodges,S.; Lyons,V.; Sayers,R.; Clarke,J.
TI Testing for TSE: Mad cows, Scrapie Sheep and Wasted Deer and Elk
QU International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - DG-18
PT Konferenz-Poster
AB With the transmission of Mad Cow Disease or Bovine Spongiform Encephalopathy (BSE) to humans in the form of new variant Creutzfeldt Jakob Disease (vCJD) there has been a significantly increased awareness of Transmissible Spongiform Encephalopathies (TSEs) and their potential threat to human health. This increased concern for the threat to human health has been accompanied by a call for increased testing to determine the true incidence of these diseases and to eliminate animals that pose a possible source of oral infection to man. Because of the large number of samples involved and the relative rapidity of the test an ELISA format (Enzyme Linked Immunosorbant Assay) has definite advantages. The Enfer TSE Test is an ELISA that has the advantages of simplicity, rapidity, high throughput, sensitivity, safety and availability in kit form. The Enfer TSE test has been approved by the European Commission and is currently marketed in Europe for the detection of BSE in cattle. It is currently used in Ireland for the screening of sheep for scrapie as well as for BSE in cattle. It is being evaluated in the US as an aid in the diagnosis of CWD in deer and elk. Data will be presented demonstrating the use of this test for the detection of PrPsc in cattle, sheep, deer and elk for a variety of samples including CNS, lymph nodes, and autolyzed samples likely to be encountered in real life situations.
AD Michael Klass, Steven Hodges, Abbott Laboratories, USA; Vanessa Lyons, Riona Sayers, John Clarke, Enfer Scientific Limited, Ireland
SP englisch
PO Deutschland