NR APLK
AU Santos Lasaosa,S.; Escalza Cortina,I.; Navas-Vinagre,I.; Pascual Millan,L.F.; Lopez del Val,L.J.; Mostacero Miguel,E.; y Cajal Junquera,S.R.
TI [Progressive myoclonic cerebellar ataxia as a manifestation of Creutzfeldt-Jakob disease]
OT Ataxia cerebelosa mioclonica progresiva como manifestacion de la enfermedad de Creutzfeldt-Jakob
QU Revista de Neurologia 2003 Sep 16-30; 37(6): 535-8
PT case reports; journal article
AB INTRODUCTION: Progressive myoclonic cerebellar ataxia is a clinical entity with an important spectrum of possible diagnoses that requires a complex and exhaustive differential diagnosis. CASE REPORT: A 53-year-old male patient with no relevant medical history who was admitted to hospital because of an unstable gait, together with mild bilateral dysymmetry and the progressive and insidious widening of the base of support. The patient's symptoms then became more pronounced and included myoclonus and a deterioration of the higher functions. The patient died four months after the onset of the symptoms. The explorations that were conducted included a pathological study of the brain, which confirmed the diagnosis of classical spongiform encephalopathy (Creutzfeldt-Jakob disease). CONCLUSIONS: Creutzfeldt-Jakob disease must be included in the differential diagnosis of progressive cerebellar ataxias.
MH Cerebellar Ataxia/*etiology/pathology; Creutzfeldt-Jakob Syndrome/*complications/*diagnosis/pathology; English Abstract; Fatal Outcome; Human; Male; Middle Aged; Myoclonus/*etiology/pathology
AD Sonia Santos Lasaosa, Inés Escalza Cortina, Inmaculada Navas Vinagre, Luis Fernando Pascual Millán, Luis Javier López del Val, Enrique Mostacero Miguel, Santiago Ramón y Cajal Junquera, Servicio de Neurologia, Hospital Clinico Universitario Lozano Blesa, Zaragoza, Espana. ssantosl@yahoo.com
SP spanisch
PO Spanien