NR APWR
AU Elsen,J.M.; Khang,T.V.T.; Clouscard,C.
TI Genetic susceptibility to subacute transmissible spongiform encephalopathies
QU Le Point Vétérinaire 1996; 28(N179): 27-32
PT Article
AB In several species susceptibility to STSE is, to a large extent, controlled by the host's genotype at Pm-p locus gene coding for the Prp prion protein, which could be the agent responsible for these diseases. Molecular analysis of the structure of the Pm-p gene in the sheep shows the segregation of alleles differing from one another by punctual mutation. A selection towards resistance to scrapie is therefore possible to consider; yet further research needs to be carried out since resistant animals could become a reservoir for infection and not be resistant to all the different strains (5 figures, 1 table, 4 boxes, 32 references).
ZR 32
SP französisch