NR AQIJ
AU Chernoff,Y.O.
TI Do amyloids remember their origin? New insights into the prion species barrier
QU Molecular Cell 2004 Apr 23; 14(2): 147-8
KZ Mol Cell. 2004 Apr 9;14(1):139-45. PMID: 15068810
PT comment; journal article
AB Excellent work demonstrates that, in the test tube, prion protein itself is responsible for its species specificity, although questions remain about whether this occurs in the same way in the organism.
MH Amyloid/genetics/*metabolism; Animals; Carrier State/transmission/veterinary; Hamsters; Human; Mice; Models, Biological; Prion Diseases/*etiology/genetics/metabolism/*transmission; Prions/chemistry/classification/genetics/*metabolism/pathogenicity; Protein Isoforms/chemistry/genetics/metabolism; Protein Processing, Post-Translational; Species Specificity; Zoonoses
AD School of Biology and Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 315 Ferst Drive, Atlanta, GA 30332, USA
SP englisch
PO USA