NR AQWS
AU Wu,D.; Stowell,C.P.
TI Prion diseases: recent developments toward diagnostic tests.
QU American Journal of Clinical Pathology 2003 Dec; 120 Suppl: S46-52
PT journal article; review; review, multicase
AB Concerns about the large-scale European crisis of bovine spongiform encephalopathy, the finding of 1 infected cow in Alberta, Canada, in 2003, and the theoretical concern of prion transmissibility in blood have renewed interest in the development of rapid, minimally invasive diagnostic assays for prion diseases. Herein we review the pathologic features, clinical manifestations, diagnostic criteria, and recent developments that may lead to new diagnostic screening assays for prion diseases.
ZR 42
MH Activins/analysis; Animals; Cattle; Human; Inhibin-beta Subunits/analysis; Prion Diseases/complications/*diagnosis; Prions/analysis/urine; Tonsil/chemistry
AD Department of Pathology, Brigham and Women's Hospital, Havard Medical School, Boston, MA, USA
SP englisch
PO USA