NR ARBE
AU Will,R.G.
TI Variant Creutzfeldt-Jakob disease
QU Folia Neuropathologica 2004; 42 Suppl A: 77-83
PT journal article; review; review, tutorial
AB Current evidence indicates that variant Creutzfeldt-Jakob disease is caused by the transmission of bovine spongiform encephalopathy to humans. The clinical and investigative features of variant CJD are relatively distinct from sporadic CJD and the neuropathological appearances are novel. The number of cases of vCJD in the UK may have peaked, but the total future number of cases of vCJD is uncertain and the possibility of secondary iatrogenic transmission via blood transfusion has recently been identified.
ZR 22
MH Age of Onset; Animals; Cattle; Central Nervous System/pathology; Comparative Study; Creutzfeldt-Jakob Syndrome/*epidemiology/*pathology/transmission; Encephalopathy, Bovine Spongiform/transmission; Great Britain/*epidemiology; Human; Public Health; Risk Factors
AD National CJD Surveillance Unit, Western General Hospital, Edinburgh, Scotland, UK. r.g.will@ed.ac.uk
SP englisch
PO Polen