NR ARCC
AU Eisenberg,D.; Marcotte,E.M.; Xenarios,I.; Yeates,T.O.
TI Protein function in the post-genomic era
QU Nature 2000 Jun 15; 405(6788): 823-6
PT journal article; review; review, tutorial
AB Faced with the avalanche of genomic sequences and data on messenger RNA expression, biological scientists are confronting a frightening prospect: piles of information but only flakes of knowledge. How can the thousands of sequences being determined and deposited, and the thousands of expression profiles being generated by the new array methods, be synthesized into useful knowledge? What form will this knowledge take? These are questions being addressed by scientists in the field known as 'functional genomics'.
ZR 26
MH Animals; Biotechnology; Computational Biology; Data Interpretation, Statistical; Genome; Phylogeny; Proteins/genetics/*physiology
AD Molecular Biology Institute and UCLA-DOE Laboratory of Structural Biology and Molecular Medicine, University of California at Los Angeles, 90095-1570, USA. david@mbi.ucla.edu
SP englisch
PO England