NR ARFG

AU anonym

TI WHO Expert Committee on Biological Standardization

QU World Health Organization Technical Report Series 2002; 910: 1-104, back cover

PT journal article; technical report

AB This report presents the recommendations of a WHO Expert Committee commissioned to coordinate activities leading to the adoption of international recommendations for the production and quality control of vaccines and other biologicals and the establishment of international biological reference materials. The report starts with a discussion of general issues brought to the attention of the Committee and provides information on issues relevant to international guidelines, recommendations and other matters related to the manufacture and quality control of biologicals. This is followed by information on the status and development of reference materials for bovine spongiform encephalopathy, various antigens, blood products, cytokines, growth factors and endocrinological substances. The second part of the report, of particular interest to manufacturers and national control authorities, contains sets of recommendations for the production and control of poliomyelitis vaccine (oral) and poliomyelitis vaccine (inactivated) and guidelines for the production and control of live attenuated Japanese encephalitis vaccine. Also included are lists of recommendations and guidelines for biological substances used in medicine, and other relevant documents.

MH Biological Products/*standards; Guidelines; Humans; International Cooperation; Japanese Encephalitis Vaccines/standards; Poliovirus Vaccine, Inactivated/standards; Poliovirus Vaccine, Oral/standards; *Quality Control; *Reference Standards; Vaccines/*standards; World Health Organization

SP englisch

PO Schweiz

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