NR ASEK
AU Seno,H.; Ishino,H.; Inagaki,T.; Iijima,M.; Kikumoto,O.; Yoshinaga,J.; Matsuura,H.; Tachiyama,Y.
TI Vascular dementia clinically resembling Creutzfeldt-Jakob- disease
QU Neuropathology 1997; 17(N2): 117-20
PT Article
AB An autopsy case of vascular dementia, clinically resembling Creutzfeldt-Jakob disease, is reported. A 74-year-old woman showed progressive dementia, transient myoclonus of the right upper arm, diffuse periodic synchronous discharges on electroencephalography, and brain atrophy on computed tomography. The duration of the illness was 17 months. Neuropathologic findings were numerous small necrotic foci in the middle and lower layers of the cerebral cortex, myelin pallor of the cerebral white matter, and fibrous thickening of the arterial and arteriolar walls in the cerebrum and cerebellum (both cortex and white matter). Vascular dementia was diagnosed. On the basis of these features, it is considered that such neuropathologic changes caused Creutzfeldt-Jakob-like symptoms, such as dementia and periodic synchronous discharges.
IN Die Autoren beschreiben den Fall einer 74-jährigen Patientin, bei der Durchblutungsstörungen zu einer Creutzfeldt-Jakob-ähnlichen Symptomatik mit einer progressiven Demenz, zeitweisen Myoklonien im rechten Oberarm und diffuse periodische synchrone Entladungen im EEG und nach 17 Monaten zum Tode führten.
ZR 17
SP englisch