NR ATTA
AU Donmez,B.; Cakmur,R.; Men,S.; Oztura,I.; Kitis,A.
TI Coexistence of movement disorders and epilepsia partialis continua as the initial signs in probable Creutzfeldt-Jakob disease
QU Movement Disorders 2005 Sep; 20(9): 1220-3
PT case reports; journal article
AB Movement disorders and epilepsy rarely occur in the early stage of Creutzfeldt-Jakob disease (CJD) but have not been reported concurrently. We report on a 47-year-old patient with probable CJD who presented with generalized chorea and focal dystonia with myoclonic jerks on the right hand. Myoclonic jerks progressed to epilepsia partialis continua within 5 days of admission to the hospital. The diagnosis of our patient was compatible with probable CJD on the basis of clinical course, electroencephalogram, and diffusion-weighted magnetic resonance imaging findings, and presence of 14-3-3 protein in cerebrospinal fluid. To our knowledge, this is the first report of a case developing both movement disorders and epilepsia partialis continua in the early stage of the disease.
MH Basal Ganglia/pathology; Caudate Nucleus/physiopathology; Creutzfeldt-Jakob Syndrome/*epidemiology/pathology; Diagnosis, Differential; Electroencephalography; Epilepsies, Partial/diagnosis/*epidemiology/physiopathology; Female; Gyrus Cinguli/physiopathology; Humans; Magnetic Resonance Imaging; Middle Aged; Movement Disorders/diagnosis/*epidemiology/physiopathology; Putamen/physiopathology; Severity of Illness Index; Thalamus/physiopathology
AD Department of Neurology, Medical School of Dokuz Eylul University; Izmir, Turkey.
SP englisch
PO USA