NR AUKC
AU Buschmann,A.; Ziegler,U.; Groschup,M.H.
TI Standardization of BSE rapid test performances and experiences gathered during the implementation of large-scale testing
QU Accreditation and Quality Assurance 2004; 9: 191-7
PT journal article
AB The accumulation of pathological prion protein is used as a diagnostic marker for transmissible spongiform encephalopathies. According to European Union (EU) regulations cattle older than 30 months of age (Germany, France, Italy, and Spain by national law >24 months) and slaughtered for human consumption must be tested by using rapid tests for bovine spongiform encephalopathy (BSE). Likewise fallen stock and clinically affected animals must be tested. This article gives a short overview of the incidence of BSE in Europe. The diagnostic hierarchy, i.e., the officially approved methodology for the confirmation of suspect rapid test cases, and the organization of the numerous laboratories involved in this large-scale testing for BSE are described. Special emphasis is given to necessary quality control measures currently in place for BSE rapid testing laboratories and to measures intended to assure a consistent performance of the commercially available rapid test kits.
ZR 0
AD A. Buschmann, U. Ziegler, M. H. Groschup, Institute for Novel and Emerging Infectious Diseases, Federal Research Centre for Virus Diseases of Animals, Boddenblick 5a, 17493 Greifswald, Isle of Riems, Germany, e-mail: martin.groschup@rie.bfav.de, Tel.: +49-38351-70, Fax: +49-38351-7191
SP englisch
PO Deutschland