NR AULV
AU Paul,J.
TI Problems with sterilization related to prion agents of transmissible subacute spongiform encephalopathies
QU Medecine et Maladies Infectieuses 1996; 26(BIS): 295-8
PT Article
AB Recent events such as the outbreak of Creutzfeldt-Jakob disease of iatrogenic origin in growth-retarded children treated with extracted hypophyseal hormones, the accidental development of bovine spongiform encephalopathy linked to the consumption of proteins of ovine and bovine origin and the confirmation of disease acquired by patients during treatment with contaminated biological tissue (grafts, implants) or with contaminated instruments have attracted the attention of health authorities. These accidental contaminations have two principal causes : the impossibility of detecting infected but apparently healthy people and the resistance of prions to all the classically employed sterilization methods. The problems raised by accidental human transmission - and more particularly by animal transmission - because of the economic incidence of ''mad cow disease'' in Great Britain on the one hand and also questions concerning the possibility of the transmission of bovine disease to humans on the other, have been the basis of community and national legal measures intended to avoid contamination in agricultural, alimentary and pharmaceutical areas.
ZR 0 Zitate
SP französisch