NR AUXS
AU anonym
AK Editorial team (eurosurveillance.weekly@hpa.org.uk), Eurosurveillance editorial office
TI Another probable case of variant CJD announced in Ireland
QU Euro Surveillance : Bulletin Europeen sur les Maladies Transmissibles = European Communicable Disease Bulletin 2005 Jul 7; 10(7): E050707.1
IA http://www.eurosurveillance.org/ew/2005/050707.asp#1
PT journal article
VT
Another case of probable variant Creutzfeldt-Jakob disease (vCJD) has been identified in Ireland [1]. Three cases of vCJD have now been reported in Ireland, although the first, in 1999, was thought not to be indigenous as the patient had lived in England for several years during the high risk period [2]. If the recent probable case is indigenous, this will be Ireland's second.
Ireland has the second highest rate of bovine spongiform encephalopathy (BSE) in cattle in the world. In 2003, an expert team at the Irish National CJD Surveillance Unit (http://www.eurocjd.ed.ac.uk/IRELAND.htm) modelled the possible risk to the Irish population based on relative exposure to BSE contaminated meat and infectivity of bovine tissue. Their analysis estimated that one case of vCJD (95% CI:0-15) would be expected [3].
vCJD appears to be transmissible by blood transfusion, as demonstrated by a case in the United Kingdom in 2003 [4]. The patient had donated blood and two patients were treated with different components of this donation. One recipient patient subsequently died shortly afterwards of an unrelated underlying condition. The recipient of the other blood component has been informed [5].
People who spent even just one year in the United Kingdom between 1980 and 1996 have been excluded from giving blood in Ireland since November 2004 (people who spent 5 years in the UK during this time have been barred since 2001, people who spent 3 years since May 2004). All people who ever received a blood transfusion since 1980 were also excluded from donating in May 2004.
References:
1. Department of Health and Children, Ireland. Probable case of variant CJD. Press release 1 July 2005. (http://www.dohc.ie/news/2005/nvCJD.html)
2. Birchard. Variant Creutzfeldt-Jakob disease found in Ireland. Lancet 1999; 353: 2221. (http://www.thelancet.com)
3. Probable case of indigenous vCJD diagnosed in Ireland. Eurosurveillance Weekly 2004; 8(46): 11/11/2004 (http://www.eurosurveillance.org/ew/2004/041111.asp#1)
4. Llewelyn CA, Hewitt PE, Knight RS, Amar K, Cousens S, Mackenzie J, et al. Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. Lancet 2004;363:417-21.
5. Irish Blood Transfusion Service. Press release. 30 June 2005. http://www.ibts.ie/press_rel.cfm?mID=6&sID=94&ssID=22&yr=2005&relID=41#41
MH Communicable Diseases, Emerging/*epidemiology; Creutzfeldt-Jakob Syndrome/*classification/*epidemiology; Disease Outbreaks/*statistics & numerical data; Humans; Incidence; Ireland/epidemiology; *Population Surveillance; Risk Assessment/*methods; Risk Factors
SP englisch
PO Frankreich