NR AUYI
AU Keyrouz,S.G.; Labib,B.T.; Sethi,R.
TI MRI and EEG findings in Heidenhain variant of Creutzfeldt-Jakob disease
QU Neurology 2006 Jul 25; 67(2): 333
PT case reports; journal article
VT A 51-year old woman was admitted with rapidly progressive memory loss, language impairment, and difficulty performing routine daily activities. Prior to admission, she was on a psychiatric ward because of visual hallucinations and abnormal behavior. She was aphasic, cortically blind and spastic with exaggerated reflexes, bilateral Babinski, and frequent multifocal myoclonic jerks. CSF 14-3-3 protein was elevated. The patient died 4 months after unrelenting progression. This patient had probable sporadic Creutzfeldt-Jakob disease (CJD), Heidenhain variant.1 The leading symptoms of a visual disorder and rapid progression have been referred to as the "Heidenhain variant" of CJD since 1954. It shows the most pronounced neuropathologic/radiologic changes in the occipital lobes.
MH Creutzfeldt-Jakob Syndrome/complications/*diagnosis; *Electroencephalography; Female; Humans; *Magnetic Resonance Imaging; Middle Aged; Muscle Spasticity/*diagnosis/etiology; Vision Disorders/*diagnosis/etiology
AD Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA. labibbishoy@uams.edu
SP englisch
PO USA