NR AVVW
AU Chang,C.C.; Eggers,S.D.; Johnson,J.K.; Haman,A.; Miller,B.L.; Geschwind,M.D.
TI Anti-GAD antibody cerebellar ataxia mimicking Creutzfeldt-Jakob disease
QU Clinical Neurology and Neurosurgery 2007 Jan; 109(1): 54-7
PT case reports; journal article; research support, n.i.h., extramural; research support, non-u.s. gov't
AB In a patient with a rapidly progressive neurological condition with ataxia and cognitive complaints, Creutzfeldt-Jakob disease (CJD) is often high in the differential, particularly when there is an elevated CSF 14-3-3 protein level. We present a case of anti-glutamic acid decarboxylase antibody (anti-GAD65) positive cerebellar ataxia associated with cognitive complaints and elevated CSF 14-3-3 protein.
MH 14-3-3 Proteins/cerebrospinal fluid; Antibodies/*metabolism; Cerebellar Ataxia/*diagnosis/etiology/*metabolism; Creutzfeldt-Jakob Syndrome/*diagnosis; Diagnosis, Differential; Female; Glutamate Decarboxylase/*immunology; Humans; Middle Aged
AD University of California San Francisco, Department of Neurology, Memory & Aging Center, Box 1207, San Francisco, CA 94143-1207, USA
SP englisch
PO Niederlande