NR AWBY
AU Benestad,S.L.; Gavier-Widen,D.
TI The 2006-European proficiency testing for the diagnosis of chronic wasting disease
QU International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre, Workshop of the Neuroprion Cervid Group - Chronic Wasting Disease (CWD): Current knowledge and European perspective 2006, 3.10.2006
PT Konferenz-Vortrag
AB Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy that affects several species of cervids. CWD has never been reported in Europe. However in most European countries only a very limited number of animals have been tested. Therefore, it is not known if the disease occurs in Europe and if the European cervids, either farmed or free-ranging species, are susceptible to CWD or to other prion diseases. A survey for CWD for the whole EU, aiming to start in the Autumn of 2006, is currently under planning. The cervids group, a working group of Neuroprion, has organized a proficiency testing with the following objectives: 1. To provide CWD material to laboratories that will be diagnosing the disease. 2. To determine if the screening and confirmatory methods available for TSEs at these laboratories are appropriate to detect CWD. 3. To obtain an estimate of the variability of results between/among the laboratories and to identify potential difficulties. 4. To offer a training exercise, including discussions on interpretation of results. Frozen and paraffin-embedded samples of brain and lymphoid tissues of elk and deer with CWD were kindly provided by THE CFIA, Canada ( Dr Balachandran). The following laboratories participated of one or more of the ring tests: NVI (Oslo, Norway), SVA (Uppsala, Sweden), VLA (Weybridge, UK), FVB.IZW (Berlin, Germany), CEA (Turin, Italy), UNIZAR (Zaragoza, Spain), LNIV (Lisbon, Portugal) and CVRL (Celbridge, Ireland). The tests applied were: rapid tests, western immunoblot and immunohistochemistry. The work is still in progress (by August 2006) and the preliminary results will be presented.
AD S.L. Benestad: National Veterinary Institute, PO Box 8156Dep., N-0033, Oslo, Norway; D. Gavier-Widén: National Veterinary Institute (SVA), 75652 Upssala, Sweden E-mail: sylvie.benestad@vetinst.no and dolores@sva.se
SP englisch
PO Italien