NR AWCQ
AU Calavas,D.; Jarrige,N.; Abrial,D.; Morignat,E.; Ducrot,C.
TI An assessment of the efficiency of the first two bans taken against BSE in France
QU International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions EPI-03
PT Konferenz-Poster
AB Following the emergence and exponential increase of the BSE epizootic in the UK, two bans have been successively put in force in France in order to control the disease: in 1990 a first ban on meat-and-bone meal in cattle feed; in 1996 a second ban on cadavers and specified risk material in farm animal feed. Despite these measures, BSE have been detected in animals born after these two bans. Out of the 989 cases detected on March 1st 2006, 847 were born between the first and second ban, and 103 after the second one. In order first to estimate the trend of the epizootic and second to understand the risk factors for BSE in France since the first ban is in force, different studies have been carried out by our teams: i) an analysis of the trend of the prevalence in the successive birth cohorts using logistic regression models; ii) a spatial analysis of the BSE prevalence over time and in relation with the density of the populations of pigs and poultry using Bayesian graphical modelling methods and based on a Poisson distribution with spatial smoothing; iii) an attempt to evidence risk factors for cases born between the two bans using a case-control study involving 182 cases and 182 matched controls using conditional logistic regression; iiii) an attempt to raise hypotheses for the contamination of cases born after the second ban using a case study. Altogether, the results of these complementary approaches, in accordance with the results of modelling issued from other team studies, allow to deliver a global frame for the trend of the epizootic since the disease emerged in France and for the risk factors for cattle infection over time. They lead finally to assess the efficiency of the first two bans implemented to control the disease. The presentation would be the occasion to present for the first time an integrated overview of these studies and their results.
AD D. Calavas, N. Jarrige, E. Morignat: AFSSA Lyon, Unité Epidémiologie, Lyon, France; D. Abrial, C. Ducrot: INRA Theix, Unité d'Epidémiologie Animale, Saint-Genès-Champanelle, France. E-mail: d.calavas@lyon.afssa.fr
SP englisch
PO Italien