NR AWLR
AU Paul,M.; Abrial,D.; Rican,S.; Jarrige,N.; Calavas,D.; Ducrot,C.
TI Feedstuff factories and BSE in France - spatial analysis
QU International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions EPI-20
PT Konferenz-Poster
AB A spatial analysis was carried out in order to analyse the reason why the risk of Bovine Spongiform Encephalopathy (BSE) was spatially heterogeneous in France, during the period following the feed ban of Meat and Bone Meal (MBM) to cattle. The hypothesis of cross-contamination between cattle and monogastric feedstuff, as well as the hypothesis of the contamination of animal by products used in animal feed (fat, phosphates) was assessed via a spatial analysis focused on the use of MBM, animal fat and bone derived minerals in factories. Data concerned the 629 BSE cases born in France after the ban of MBM (July 1990) and detected between July 1st, 2001 and December 31, 2005, when the surveillance system was optimal and not spatially biased. Animal density data were provided by the 2000 census and the data on the 327 feedstuff factories producing compound feed for cattle were collected from administrative inspection. The first step of the analysis was to define areas concerned by the delivery areas of the same factories and the level of each risk factor, as well as the spatial risk of BSE. The second step analysed the crude link between the BSE risk and the risk factors at the area level, based on categorisation and chi square test. Finally the third step was a disease mapping, based on hierarchical Bayesian models (Poisson distribution with spatial smoothing and covariates) elaborated by directed acyclic graphs method. Parameters were estimated by a Markov Chain Monte Carlo simulation method. The results evidenced the role on the BSE risk of the use of MBM for monogastrics in the factories, pointing out the cross-contamination between cattle and monogastric feedstuffs as the main probable source of infection for the BSE cases born after the ban of MBM to cattle.
AD M. Paul, D. Abrial, C. Ducrot: INRA, Départ. Santé Animale, Unité d'Epidémiologie Animale, Saint- Genès-Champanelle, France; S. Rican: Laboratoire Espace et Santé, Université Nanterre Paris X, France; N. Jarrige, D. Calavas: AFSSA Lyon, Unité Epidémiologie, Lyon, France. E-mail: ducrot@clermont.inra.fr
SP englisch
PO Italien