NR AXJP
AU Bona,M.C.; Caramelli,M.; Maurella,C.; Nonno,R.; Peletto,S.; Porcario,C.; Possidente,R.; Ru,G.
TI Epidemiology of Atypical Scrapie In Italy
QU International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Epidemiology, Risk Assessment and Transmission P04.87
IA http://www.prion2007.com/pdf/Prion Book of Abstracts.pdf
PT Konferenz-Poster
AB Since 1995 to 2006, 310 scrapie outbreaks were reported in Italy: 267 sheep flocks, 29 goat herds, 14 mixed flocks. Due to the implementation of the compulsory system of active surveillance in January 2002, many new cases have been recorded leading to a strong increase of scrapie incidence. The shift in September 2004 from using Prionics to BioRad allowed the identification of atypical scrapie cases, however only on May 2005 a first atypical case in a sheep was detected. . Aim of our work was to describe the epidemiology of atypical scrapie in Italy during the period 2005-2006. Outbreaks were characterized on the basis of disease distribution by time, space and animal or flock features. Age of affected animals were compared by type strain (classical vs. atypical) and by species using the Mann Whitney test. 28 cases in sheep and 6 in goats have been confirmed up to December 2006. Only a couple of secondary sheep cases in the same flocks were identified. All the cases were classified as Nor98-like. Compared to classical scrapie that has a more even geographical distribution, the atypical cases seem to be scattered above all in the central-southern regions of the country. Whereas in sheep the atypical cases are clearly older than classical ones, in goat the same age classes are affected by the two strains. The genotype distribution doesn't show significant differences compared with that reported in the rest of Europe. So far only few hints are available regarding the transmissibility of the disease, its origin or its aetiology. Nevertheless the collection of these data seem to be crucial in order to increase the understanding of the disease and to implement an efficient eradication plan.
AD M.C. Bona, M. Caramelli, S. Peletto, G. Ru, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Italy; C. Maurella, Istituto Zooprofilattico del Piemonte, Ligurie e Valle d'Aosta; R. Nonno, Istituto Superiore di Sanità; C. Porcario, R. Possidente, Istituto Zooprofilattico del Piemonte, Liguria e Valle d'Aosta
SP englisch
PO Schottland