NR AXKM
AU Comoy,E.; Letessier,F.; Delaunay,C.; Deslys,J.P.
TI Inactivation of Prion Infectivity in Processed Meat Through Appertisation
QU International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Epidemiology, Risk Assessment and Transmission P04.48
IA http://www.prion2007.com/pdf/Prion Book of Abstracts.pdf
PT Konferenz-Poster
AB
During the last several years, measures have been taken in most European countries to limit contamination of human food with BSE-contaminated material, with special attention to mechanically recovered meat. We have evaluated the possibility of the technique of appertisation to increase the level of safety of processed meat.
Artificial contamination of meat products was performed using different doses of a mouse-adapted BSE strain (6PB1) and submitted to different appertisation conditions (130-133 °). A reduction of 4 to 5 logs of infectivity was obtained an input dose of 1% brain homogenate, but substantially less reduction with an input dose of 10% brain homogenate, associated with aggregates of PK resistant PrP. This technique could be useful under conditions in which highly infected tissue is removed and destroyed before treatment.
AD E. Comoy, F. Letessier, C. Delaunay, J.P. Deslys, CEA/DSV/IMETI/SEPIA, France
SP englisch
PO Schottland
EA pdf-Datei und Poster (Posterautoren ergänzt um L. Challier)