NR AYIK

AU Smetana,J.; Vackova,M.; Chlibek,R.

TI [Prion diseases]

OT Prionove nemoci

QU Epidemiologie, Mikrobiologie, Imunologie 2007 Aug; 56(3): 112-8

PT english abstract; journal article; review

AB The group of prion diseases includes many diagnoses which have been long known. Nevertheless, the general awareness of these diseases increased substantially with the outbreaks of bovine spongiform encephalopathy (BSE) and the emergence of a new variant of Creutzfeldt-Jakob disease (nvCJD) at the close of the XXth century. Although major advances have been made in this field, further research is required to better understand these diseases. Many questions related e.g. to the accurate definition of the causative agent, pathogenesis, diagnosis and treatment still need to be addressed. The aim of this article is to present the latest knowledge of the etiology and epidemiology of these diseases with a focus on BSE and nvCJD, including measures taken for their control.

ZR 0

MH Animals; Cattle; Cattle Diseases/transmission; Creutzfeldt-Jakob Syndrome/diagnosis/transmission; *Encephalopathy, Bovine Spongiform/diagnosis/transmission; Humans; *Prion Diseases

AD Univerzita obrany, Katedra epidemiologie Fakulty vojenskeho zdravotnictvi v Hradci Kralove. smetana@pmfhk.cz

SP tschechisch

PO Tschechische Republik

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