AUGP - Barnewitz,K.; Maringer,M.; Mitteregger,G.; Giese,A.; Bertsch,U.; Kretzschmar,H.A. - Unaltered prion protein cleavage in plasminogen-deficient mice - Neuroreport 2006 Apr 3; 17(5): 527-30
ASOA - Bertsch,U.; Winklhofer,K.F.; Hirschberger,T.; Bieschke,J.G.; Weber,P.; Hartl,F.U.; Tavan,P.; Tatzelt,J.; Kretzschmar,H.A.; Giese,A. - Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets - Journal of Virology 2005 Jun; 79(12): 7785-91
ARDE - Bertsch,U.; Winklhofer,K.F.; Hirschberger,T.; Bieschke,J.G.; Weber,P.; Hartl,F.U.; Tavan,P.; Tatzelt,J.; Kretzschmar,H.A.; Giese,A. - Systematic identification of anti-prion drugs by high-throughput screening based on scanning for intensely fluorescent targets (SIFT) - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Vortrag V-21
AOQI - Bertsch,U.; Giese,A.; Bieschke,J.G.; Weber,P.; Levin,J.; Kretzschmar,H.A. - Screening for potential prion disease therapeutics using a single-molecule fluorescence assay of PrPc association to prion rods in vitro - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - IV-16
AQVH - Bieschke,J.G.; Weber,P.; Sarafoff,N.; Beekes,M.; Giese,A.; Kretzschmar,H.A. - Autocatalytic self-propagation of misfolded prion protein - Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 17; 101(33): 12207-11
AOQK - Bieschke,J.G.; Weber,P.; Sarafoff,N.; Beekes,M.; Giese,A.; Kretzschmar,H.A. - Loss of infectivity in autocatalytic self-propagation of misfolded prion protein - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-48
AOQL - Bieschke,J.G.; Weber,P.; Giese,A.; Bertsch,U.; Kretzschmar,H.A. - Single molecule detection and characterization of PrPsc - towards a blood test for prion disease - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - DG-57
ABIJ - Bieschke,J.G.; Giese,A.; Schulz-Schaeffer,W.J.; Zerr,I.; Poser,S.; Eigen,M.; Kretzschmar,H.A. - Ultrasensitive detection of pathological prion protein aggregates by dual-color scanning for intensely fluorescent targets - Proceedings of the National Academy of Sciences of the United States of America 2000 May 9; 97(10): 5468-73
ABTB - Brown,D.R.; Qin,K.; Herms,J.W.; Madlung,A.; Manson,J.; Strome,R.; Fraser,P.E.; Kruck,T.; von Bohlen,A.; Schulz-Schaeffer,W.J.; Giese,A.; Westaway,D.; Kretzschmar,H.A. - The cellular prion protein binds copper in vivo - Nature 1997 Dec 18-25; 390(6661): 684-7
ADQY - Dürig,J.; Giese,A.; Schmücker,U.; Kretzschmar,H.A.; Dührsen,U. - Decreased prion protein expression in human peripheral blood leucocytes from patients with paroxysmal nocturnal haemoglobinuria - British Journal of Haematology 2001 Mar; 112(3): 658-62
ADQZ - Dürig,J.; Giese,A.; Schulz-Schaeffer,W.J.; Rosenthal,C.; Schmücker,U.; Bieschke,J.G.; Dührsen,U.; Kretzschmar,H.A. - Differential constitutive and activation-dependent expression of prion protein in human peripheral blood leucocytes - British Journal of Haematology 2000 Mar; 108(3): 488-96
AUTB - Ebner,S.; Sethi,S.K.; Giese,A.; Hinske,C.; Kretzschmar,H.A. - Basic principles underlying the effect of multiple administrations of CpG-Oligodeoxynucleotides on prion disease in mice - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Poster: Therapie THE-07
ATNH - Ebner,S.; Sethi,S.K.; Giese,A.; Hinske,C.; Kretzschmar,H.A. - Basic principles underlying the effect of multiple administrations of CpG-Oligodeoxynucleotides on prion disease in mice - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Human prions, risk of blood products, and therapy HUMAN-05
ATLR - Geue,H.; Weber,P.; Kramer,K.; Giese,A.; Kretzschmar,H.A.; Hock,B. - Development of specific recombinant anti-PrPsc antibodies - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Diagnosis DIA-55
AREQ - Geue,H.; Weber,P.; Kramer,K.; Giese,A.; Kretzschmar,H.A.; Hock,B. - Development of specific recombinant anti-PrPsc antibodies - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Poster DIA-03
AXND - Giese,A.; Wagner,J.; Bertsch,U.; Mitteregger,G.; Eiden,M.; Geissen,M.; Leidel,F.; Hirschberger,T.; Tavan,P.; Tatzelt,J.; Schmidt,B.; Groschup,M.H.; Kretzschmar,H.A. - Systematic Development of New Compounds for the Causal Therapy of Prion Diseases based on Molecular High-throughput Screening - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Protein Misfolding P01.17
AUQQ - Giese,A.; Weber,P.; Piening,N.; Mitteregger,G.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A. - Cell-free formation of misfolded prion protein with genuine prion infectivity - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Vortrag V-09
AUAG - Giese,A.; Buchholz,M.; Herms,J.W.; Kretzschmar,H.A. - Mouse brain synaptosomes accumulate copper-67 efficiently by two distinct processes independent of cellular prion protein - Journal of Molecular Neuroscience 2005; 27(3): 347-54
ATFR - Giese,A.; Weber,P.; Piening,N.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A. - Cell-free generation of prion infectivity by serial PMCA - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Oral sessions ORAL-22
ARDX - Giese,A.; Levin,J.; Bertsch,U.; Kretzschmar,H.A. - Effect of metal ions on de novo aggregation of full-length prion protein - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Poster GL-06
AQYC - Giese,A.; Levin,J.; Bertsch,U.; Kretzschmar,H.A. - Effect of metal ions on de novo aggregation of full-length prion protein - Biochemical and Biophysical Research Communications 2004 Aug 6; 320(4): 1240-6
AOTB - Giese,A.; Bader,B.; Bieschke,J.G.; Schaffar,G.; Odoy,S.; Kahle,P.J.; Haass,C.; Kretzschmar,H.A. - Dual-colour Scanning For Intensely Fluorescent Targets (SIFT) Allows Differential Monitoring of Co-aggregating Amyloidogenic Proteins - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-49
AEOL - Giese,A.; Kretzschmar,H.A. - Prion-induced neuronal damage - the mechanisms of neuronal destruction in the subacute spongiform encephalopathies - Current Topics in Microbiology and Immunology 2001; 253: 203-17
AEOM - Giese,A.; Bieschke,J.G.; Eigen,M.; Kretzschmar,H.A. - Putting prions into focus: application of single molecule detection to the diagnosis of prion diseases. - Archives of Virology. Supplementum 2000(16): 161-71
AEON - Giese,A.; Brown,D.R.; Groschup,M.H.; Feldmann,C.; Haist,I.; Kretzschmar,H.A. - Role of microglia in neuronal cell death in prion disease - Brain Pathology 1998 Jul; 8(3): 449-57
AQAU - Giese,A.; Schulz-Schaeffer,W.J.; Windl,O.; Kretzschmar,H.A. - Rinderwahn und Creutzfeldt-Jakob-Krankheit - Neue Erkenntnisse der Prionforschung - Deutsches Ärzteblatt 1996 Apr 5; 93(14): C-645-7
AEOO - Giese,A.; Groschup,M.H.; Hess,B.; Kretzschmar,H.A. - Neuronal cell death in scrapie-infected mice is due to apoptosis - Brain Pathology 1995 Jul; 5(3): 213-21
ATRF - Hepp,A.K.; Weber,P.; Bertsch,U.; Giese,A.; Kretzschmar,H.A. - Binding Dynamics of PrPc to raft-like Liposome Membranes - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Structure of PrP and molecular determinants of infectivity STRCT-21
AOTY - Hepp,A.K.; Bieschke,J.G.; Giese,A.; Bertsch,U.; Kretzschmar,H.A. - Binding dynamics of PrPc to raft-like liposome membranes - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-86
AFIE - Herms,J.W.; Tings,T.; Gall,S.; Madlung,A.; Giese,A.; Siebert,H.; Schurmann,P.; Windl,O.; Brose,N.; Kretzschmar,H.A. - Evidence of presynaptic location and function of the prion protein - Journal of Neuroscience 1999 Oct 15; 19(20): 8866-75
AUSG - Hinske,C.; Sethi,S.K.; Kerksiek,K.; Giese,A.; Wagner,J.; Wagner,I.; Ebner,S.; Brocker,T.; Kretzschmar,H.A. - Role of dendritic cells (DC) after oral and intraperitoneal transmission of scrapie - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Poster: Pathogenese/Infektion PATH-07
ATPA - Hinske,C.; Sethi,S.K.; Kerksiek,K.; Giese,A.; Wagner,J.; Ebner,S.; Brocker,T.; Kretzschmar,H.A. - Role of dendritic cells (DC) after oral and intraperitoneal transmission of scrapie - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Pathogenesis PATH-11
ATOP - Hirschberger,T.; Bertsch,U.; Youssef,S.; Kretzschmar,H.A.; Giese,A.; Tavan,P. - Screening for New Anti-Prion Compounds based on SIFT and Automated Data Analysis - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Human prions, risk of blood products, and therapy HUMAN-39
AREK - Hirschberger,T.; Bertsch,U.; Winklhofer,K.F.; Tatzelt,J.; Kretzschmar,H.A.; Tavan,P.; Giese,A. - Structure-Activity Relationships of N'-Benzylidene-Benzohydrazides as Anti-Prion Drugs - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Poster GL-19
AGUV - Kretzschmar,H.A.; Tings,T.; Madlung,A.; Giese,A.; Herms,J.W. - Function of PrPc as a copper-binding protein at the synapse - Archives of Virology. Supplementum 2000(16): 239-49
AGUR - Kretzschmar,H.A.; Giese,A.; Zerr,I.; Windl,O.; Schulz-Schaeffer,W.J.; Skworc,K.; Poser,S. - The German FFI cases - Brain Pathology 1998 Jul; 8(3): 559-61
AGUX - Kretzschmar,H.A.; Giese,A.; Brown,D.R.; Herms,J.W.; Keller,B.; Schmidt,B.; Groschup,M.H. - Cell death in prion disease - Journal of Neural Transmission. Supplementum 1997; 50: 191-210
AQFF - Kretzschmar,H.A.; Giese,A.; Schulz-Schaeffer,W.J.; Windl,O.; Groschup,M.H.; Riesner,D. - Besteht ein Zusammenhang zwischen BSE und Creutzfeldt-Jakob-Krankheit? - Deutsches Ärzteblatt 1996 Apr 12; 93(15): C-684-5
ASKH - Levin,J.; Bertsch,U.; Kretzschmar,H.A.; Giese,A. - Single particle analysis of manganese-induced prion protein aggregates - Biochemical and Biophysical Research Communications 2005 Apr 22; 329(4): 1200-7
AOVU - Levin,J.; Giese,A.; Bieschke,J.G.; Weber,P.; Bertsch,U.; Kretzschmar,H.A. - Probing the molecular composition of prion protein aggregates by dual-colour SIFT - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - DG-55
AWLD - Notari,S.; Capellari,S.; Langeveld,J.P.M.; Giese,A.; Gambetti,P.; Kretzschmar,H.A.; Parchi,P. - Human PrPsc "typing" pitfalls associated with the use of type 1 selective antibodies combined with relative inefficient hydrolysis of PrPsc by proteinase K - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PR-27
ATOD - Notari,S.; Capellari,S.; Giese,A.; Grassi,J.; Ghetti,B.; Gambetti,P.; Kretzschmar,H.A.; Parchi,P. - Heterogeneity of truncated fragments distinct from PrP27-30 correlates with clinico-pathological subtypes of Creutzfeldt-Jakob disease - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Human prions, risk of blood products, and therapy HUMAN-27
AQNG - Notari,S.; Capellari,S.; Giese,A.; Westner,I.; Baruzzi,A.; Ghetti,B.; Gambetti,P.; Kretzschmar,H.A.; Parchi,P. - Effects of different experimental conditions on the PrPsc core generated by protease digestion: implications for strain typing and molecular classification of CJD. - The Journal of Biological Chemistry 2004 Apr 16; 279(16): 16797-804
AOXM - Notari,S.; Capellari,S.; Giese,A.; Westner,I.; Ghetti,B.; Gambetti,P.; Kretzschmar,H.A.; Parchi,P. - Effects of different experimental conditions on the PrPsc core generated by protease digestion: Implications for strain typing and molecular classification of CJD - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - DG-75
AJCI - Otto,M.; Wiltfang,J.; Schütz,E.; Zerr,I.; Otto,A.; Pfahlberg,A.; Gefeller,O.; Uhr,M.; Giese,A.; Weber,T.; Kretzschmar,H.A.; Poser,S. - Diagnosis of Creutzfeldt-Jakob disease by measurement of S100 protein in serum: prospective case-control study. - British Medical Journal 1998 Feb 21; 316(7131): 577-82
AJET - Parchi,P.; Giese,A.; Capellari,S.; Brown,P.; Schulz-Schaeffer,W.J.; Windl,O.; Zerr,I.; Budka,H.; Kopp,N.; Piccardo,P.; Poser,S.; Rojiani,A.; Streichenberger,N.; Julien,J.; Vital,C.; Ghetti,B.; Gambetti,P.; Kretzschmar,H.A. - Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects - Annals of Neurology 1999 Aug; 46(2): 224-33
AJEX - Parchi,P.; Capellari,S.; Chen,S.G.; Petersen,R.B.; Gambetti,P.; Kopp,N.; Brown,P.; Kitamoto,T.; Tateishi,J.; Giese,A.; Kretzschmar,H.A. - Typing prion isoforms - Nature 1997 Mar 20; 386(6622): 232-4
AVNW - Piening,N.; Weber,P.; Högen,T.; Beekes,M.; Kretzschmar,H.A.; Giese,A. - Photo-induced crosslinking of prion protein oligomers and prions - Amyloid 2006 Jun; 13(2): 67-77
ARJF - Piening,N.; Weber,P.; Giese,A.; Kretzschmar,H.A. - Breakage of PrP aggregates is essential for efficient autocatalytic propagation of misfolded prion protein - Biochemical and Biophysical Research Communications 2005 Jan 14; 326(2): 339-43
AJOG - Poser,S.; Zerr,I.; Schroeter,A.; Otto,M.; Giese,A.; Steinhoff,B.J.; Kretzschmar,H.A. - Clinical and differential diagnosis of Creutzfeldt-Jakob disease - Archives of Virology. Supplementum 2000(16): 153-9
ASVV - Sarafoff,N.I.; Bieschke,J.G.; Giese,A.; Weber,P.; Bertsch,U.; Kretzschmar,H.A. - Automated PrPres amplification using indirect sonication - Journal of Biochemical and Biophysical Methods 2005 Jun 30; 63(3): 213-21
AOYS - Sarafoff,N.I.; Bieschke,J.G.; Giese,A.; Weber,P.; Piening,N.; Bertsch,U.; Kretzschmar,H.A. - Munich Prion Cycler (MPC) - an automated PMCA machine for therapeutic and diagnostic studies in prion diseases - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - IV-10
AWXH - Schiffer,N.W.; Broadley,S.A.; Hirschberger,T.; Tavan,P.; Kretzschmar,H.A.; Giese,A.; Haass,C.; Hartl,F.U.; Schmid,B. - Identification of anti-prion compounds as efficient inhibitors of polyglutamine protein aggregation in a zebrafish model - The Journal of Biological Chemistry 2007 Mar 23; 282(12): 9195-203
AKPA - Schulz-Schaeffer,W.J.; Tschöke,S.; Kranefuss,N.; Dröse,W.; Hause-Reitner,D.; Giese,A.; Groschup,M.H.; Kretzschmar,H.A. - The paraffin-embedded tissue blot detects PrPsc early in the incubation time in prion diseases - American Journal of Pathology 2000 Jan; 156(1): 51-6
AKPB - Schulz-Schaeffer,W.J.; Giese,A.; Windl,O.; Kretzschmar,H.A. - Polymorphism at codon 129 of the prion protein gene determines cerebellar pathology in Creutzfeldt-Jakob disease - Clinical Neuropathology 1996 Nov-Dec; 15(6): 353-7
AKYJ - Skworc,K.H.; Windl,O.; Schulz-Schaeffer,W.J.; Giese,A.; Bergk,J.; Nägele,A.; Vieregge,P.; Zerr,I.; Poser,S.; Kretzschmar,H.A. - Familial Creutzfeldt-Jakob disease with a novel 120-bp insertion in the prion protein gene - Annals of Neurology 1999 Nov; 46(5): 693-700
ASUG - Stork,M.; Giese,A.; Kretzschmar,H.A.; Tavan,P. - Molecular dynamics simulations indicate a possible role of parallel beta-helices in seeded aggregation of poly-Gln - Biophysical Journal 2005 Apr; 88(4): 2442-51
AREJ - Stork,M.; Giese,A.; Kretzschmar,H.A.; Tavan,P. - Molecular Model for the Scrapie Prion Protein: Trimer of Triangular Parallel Beta-Helices - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Poster GL-18
AXYN - Weber,P.; Giese,A.; Piening,N.; Mitteregger,G.; Reznicek,L.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A. - Size Matters - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Protein Misfolding P01.49
AXDU - Weber,P.; Giese,A.; Piening,N.; Mitteregger,G.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A. - Generation of genuine prion infectivity by serial PMCA - Veterinary Microbiology 2007 Aug 31; 123(4): 346-57
AVOF - Weber,P.; Giese,A.; Piening,N.; Mitteregger,G.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A. - Cell-free formation of misfolded prion protein with authentic prion infectivity - Proceedings of the National Academy of Sciences of the United States of America 2006 Oct 24; 103(43): 15818-23
AUSI - Weber,P.; Giese,A.; Piening,N.; Mitteregger,G.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A. - Cell-free formation of misfolded prion protein with genuine prion infectivity - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Poster: Pathogenese/Infektion PATH-09
ATQL - Weber,P.; Piening,N.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A.; Giese,A. - In vitro generated misfolded prion protein is infectious - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Structure of PrP and molecular determinants of infectivity STRCT-01
ARDU - Weber,P.; Geue,H.; Giese,A.; Bertsch,U.; Westner,I.; Kretzschmar,H.A. - Optimierung von Prion rod-Präparationen - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Poster GL-03
AMQI - Windl,O.; Giese,A.; Schulz-Schaeffer,W.J.; Zerr,I.; Skworc,K.; Arendt,S.; Oberdieck,C.; Bodemer,M.; Poser,S.; Kretzschmar,H.A. - Molecular genetics of human prion diseases in Germany - Human Genetics 1999 Sep; 105(3): 244-52
AMZD - Zerr,I.; Schulz-Schaeffer,W.J.; Giese,A.; Bodemer,M.; Schröter,A.; Henkel,K.; Tschampa,H.J.; Windl,O.; Pfahlberg,A.; Steinhoff,B.J.; Gefeller,O.; Kretzschmar,H.A.; Poser,S. - Current clinical diagnosis in Creutzfeldt-Jakob disease: identification of uncommon variants. - Annals of Neurology 2000 Sep; 48(3): 323-9
AMZF - Zerr,I.; Giese,A.; Windl,O.; Kropp,S.; Schulz-Schaeffer,W.J.; Riedemann,C.; Skworc,K.; Bodemer,M.; Kretzschmar,H.A.; Poser,S. - Phenotypic variability in fatal familial insomnia (D178N-129M) genotype - Neurology 1998 Nov; 51(5): 1398-405
AIRI - Murphy,C.; Breen,K.C.; Rogers,M.; Giese,M. - Interferon gamma and prostaglandin in BSE-infected cattle - Cytokine 2001 Feb 7; 13(3): 169-73