ASOA - Bertsch,U.; Winklhofer,K.F.; Hirschberger,T.; Bieschke,J.G.; Weber,P.; Hartl,F.U.; Tavan,P.; Tatzelt,J.; Kretzschmar,H.A.; Giese,A. - Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets - Journal of Virology 2005 Jun; 79(12): 7785-91
ARDE - Bertsch,U.; Winklhofer,K.F.; Hirschberger,T.; Bieschke,J.G.; Weber,P.; Hartl,F.U.; Tavan,P.; Tatzelt,J.; Kretzschmar,H.A.; Giese,A. - Systematic identification of anti-prion drugs by high-throughput screening based on scanning for intensely fluorescent targets (SIFT) - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Vortrag V-21
ARBO - Beyreuther,K.; Biesalski,H.K.; Dingermann,T.; Kretzschmar,H.A.; Multhaup,G.; Tatzelt,J.; Wolfram,G. - Hohenheim Consensus Talks on Bovine Spongiform Encephalopathy (BSE) - Hohenheimer Konsensusgespräch ?BSE? - Aktuelle Ernährungsmedizin 2002 Okt; 27(5): 304-14
ABKI - Blochberger,T.C.; Cooper,C.M.; Peretz,D.; Tatzelt,J.; Griffith,O.H.; Baldwin,M.A.; Prusiner,S.B. - Prion protein expression in Chinese hamster ovary cells using a glutamine synthetase selection and amplification system - Protein Engineering 1997 Dec; 10(12): 1465-73
ATZW - Dumpitak,C.; Beekes,M.; Weinmann,N.; Metzger,S.; Winklhofer,K.F.; Tatzelt,J.; Riesner,D. - The polysaccharide scaffold of PrP 27-30 is a common compound of natural prions and consists of alpha-linked polyglucose - Biological Chemistry 2005 Nov; 386(11): 1149-55
AXND - Giese,A.; Wagner,J.; Bertsch,U.; Mitteregger,G.; Eiden,M.; Geissen,M.; Leidel,F.; Hirschberger,T.; Tavan,P.; Tatzelt,J.; Schmidt,B.; Groschup,M.H.; Kretzschmar,H.A. - Systematic Development of New Compounds for the Causal Therapy of Prion Diseases based on Molecular High-throughput Screening - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Protein Misfolding P01.17
AEOQ - Gilch,S.; Winklhofer,K.F.; Groschup,M.H.; Nunziante,M.; Lucassen,R.W.; Spielhaupter,C.; Muranyi,W.; Riesner,D.; Tatzelt,J.; Schätzl,H.M. - Intracellular re-routing of prion protein prevents propagation of PrPsc and delays onset of prion disease - EMBO Journal 2001 Aug 1; 20(15): 3957-66
AOGC - Heller,U.; Winklhofer,K.F.; Heske,J.; Reintjes,A.; Tatzelt,J. - Post-translational import of the prion protein into the endoplasmic reticulum interferes with cell viability: A critical role for the putative transmembrane domain. - The Journal of Biological Chemistry 2003 Sep 19; 278(38): 36139-47
APHW - Heske,J.; Heller,U.; Winklhofer,K.F.; Tatzelt,J. - The C-terminal globular domain of the prion protein is necessary and sufficient for import into the endoplasmic reticulum - The Journal of Biological Chemistry 2004 Feb 13; 279(7): 5435-43
AVDL - Hirschberger,T.; Stork,M.; Schropp,B.; Winklhofer,K.F.; Tatzelt,J.; Tavan,P. - Structural instability of the prion protein upon M205S/R mutations revealed by molecular dynamics simulations - Biophysical Journal 2006 Jun 1; 90(11): 3908-18
AREK - Hirschberger,T.; Bertsch,U.; Winklhofer,K.F.; Tatzelt,J.; Kretzschmar,H.A.; Tavan,P.; Giese,A. - Structure-Activity Relationships of N'-Benzylidene-Benzohydrazides as Anti-Prion Drugs - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Poster GL-19
ARQU - Kiachopoulos,S.; Bracher,A.; Winklhofer,K.F.; Tatzelt,J. - Pathogenic mutations located in the hydrophobic core of the prion protein interfere with folding and attachment of the glycosylphosphatidylinositol anchor - The Journal of Biological Chemistry 2005 Mar 11; 280(10): 9320-9
ARDC - Kiachopoulos,S.; Rambold,A.S.; Heske,J.; Winklhofer,K.F.; Tatzelt,J. - Mistargeting of the prion protein to the cytosol; mechanism and pathophysiological consequences - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Vortrag V-19
AREN - Kiachopoulos,S.; Heske,J.; Tatzelt,J.; Winklhofer,K.F. - Misfolding of the prion protein in the secretory pathway and at the plasma membrane; implications for prion diseases - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Poster GL-22
AQLK - Kiachopoulos,S.; Heske,J.; Tatzelt,J.; Winklhofer,K.F. - Misfolding of the prion protein at the plasma membrane induces endocytosis, intracellular retention and degradation - Traffic (Copenhagen, Denmark) 2004 Jun; 5(6): 426-36
ARRG - Leffers,K.W.; Schell,J.; Jansen,K.; Lucassen,R.W.; Kaimann,T.K.; Nagel-Steger,L.; Tatzelt,J.; Riesner,D. - The structural transition of the prion protein into its pathogenic conformation is induced by unmasking hydrophobic sites - Journal of Molecular Biology 2004 Nov 26; 344(3): 839-53
AUIS - Miesbauer,M.; Bamme,T.; Riemer,C.; Oidtmann,B.; Winklhofer,K.F.; Baier,M.; Tatzelt,J. - Prion protein-related proteins from zebrafish are complex glycosylated and contain a glycosylphosphatidylinositol anchor - Biochemical and Biophysical Research Communications 2006 Mar 3; 341(1): 218-24
ATGZ - Miesbauer,M.; Bamme,T.; Riemer,C.; Oidtmann,B.; Winklhofer,K.F.; Baier,M.; Tatzelt,J. - Biochemical characterization of prion proteins from zebra fish - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Cell Biology of PrPc and PrPsc CELL-05
AVTN - Rambold,A.S.; Miesbauer,M.; Rapaport,D.; Bartke,T.; Baier,M.; Winklhofer,K.F.; Tatzelt,J. - Association of Bcl-2 with misfolded prion protein is linked to the toxic potential of cytosolic PrP - Molecular Biology of the Cell 2006 Aug; 17(8): 3356-68
AUSD - Rambold,A.S.; Miesbauer,M.; Rapaport,D.; Bartke,T.; Baier,M.; Winklhofer,K.F.; Tatzelt,J. - Recruitment of Bcl-2 to misfolded prion protein is linked to the toxic potential of cytosolic PrP - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Poster: Pathogenese/Infektion PATH-04
AOYG - Riesner,D.; Leffers,K.W.; Wille,H.; Jansen,K.; Schell,J.; Tatzelt,J.; Prusiner,S.B. - Dimers, oligomers, multimers, and fibrils: Induction and characterization of different intermediates of PrP refolding - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Oral sessions OS-08
AKME - Schätzl,H.M.; Laszlo,L.; Holtzman,D.M.; Tatzelt,J.; DeArmond,S.J.; Weiner,R.I.; Mobley,W.C.; Prusiner,S.B. - A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis - Journal of Virology 1997 Nov; 71(11): 8821-31
AKQI - Scott,M.R.D.; Groth,D.; Tatzelt,J.; Torchia,M.; Tremblay,P.; DeArmond,S.J.; Prusiner,S.B. - Propagation of prion strains through specific conformers of the prion protein - Journal of Virology 1997 Dec; 71(12): 9032-44
ATRR - Stork,M.; Hirschberger,T.; Schropp,B.; Winklhofer,K.F.; Tatzelt,J.; Tavan,P. - Structural Instability of the Prion Protein upon M205S/R Mutations Revealed by Molecular Dynamics Simulations - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Structure of PrP and molecular determinants of infectivity STRCT-33
AXXJ - Tamgüney,G.; Giles,K.; Glidden,D.V.; Lessard,P.; Wille,H.; Legname,G.; Tremblay,P.; Groth,D.F.; Yehiely,F.; Korth,C.; Moore,R.C.; Tatzelt,J.; Rubenstein,E.; Boucheix,C.; Lisanti,M.P.; Dwek,R.A.; Rudd,P.M.; Sisodia,S.S.; Moskovitz,J.; Epstein,R.J.; Dawson Cruz,T.C.; Kuziel,W.A.; Maeda,N.; Pagoulatos,G.N.; Sap,J.; Ashe,K.H.; Carlson,G.A.; Tesseur,I.; Wyss-Coray,T.; Mucke,L.; Mahley,R.W.; Cohen,F.E.; Prusiner,S.B. - A Search for Auxiliary Proteins in Prion Replication - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Protein Misfolding P01.62
AWVE - Tatzelt,J.; Schätzl,H.M. - Molecular basis of cerebral neurodegeneration in prion diseases - The FEBS Journal 2007 Feb; 274(3): 606-11
ATFZ - Tatzelt,J. - Misfolding of PrP in the cytosol: mechanism of toxicity and the role of molecular chaperones - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Oral sessions ORAL-30
ARTS - Tatzelt,J.; Winklhofer,K.F. - Folding and misfolding of the prion protein in the secretory pathway - Amyloid 2004 Sep; 11(3): 162-72
AOZR - Tatzelt,J.; Heller,U.; Heske,J.; Winklhofer,K.F. - Misfolding of the prion protein in the cytosol and in the endoplasmic reticulum - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Oral sessions OS-10
ALME - Tatzelt,J.; Groth,D.F.; Torchia,M.; Prusiner,S.B.; DeArmond,S.J. - Kinetics of prion protein accumulation in the CNS of mice with experimental scrapie - Journal of Neuropathology and Experimental Neurology 1999 Dec; 58(12): 1244-9
ALMF - Tatzelt,J.; Voellmy,R.; Welch,W.J. - Abnormalities in stress proteins in prion diseases - Cellular and Molecular Neurobiology 1998 Dec; 18(6): 721-9
ALMG - Tatzelt,J.; Prusiner,S.B.; Welch,W.J. - Chemical chaperones interfere with the formation of scrapie prion protein - EMBO Journal 1996 Dec 2; 15(23): 6363-73
ALMH - Tatzelt,J.; Maeda,N.; Pekny,M.; Yang,S.L.; Betsholtz,C.; Eliasson,C.; Cayetano-Canlas,J.; Camerino,A.P.; DeArmond,S.J.; Prusiner,S.B. - Scrapie in mice deficient in apolipoprotein E or glial fibrillary acidic protein - Neurology 1996 Aug; 47(2): 449-53
ALMI - Tatzelt,J.; Zuo,J.R.; Voellmy,R.; Scott,M.R.D.; Hartl,U.; Prusiner,S.B.; Welch,W.J. - Scrapie prions selectively modify the stress response in neuroblastoma cells - Proceedings of the National Academy of Sciences of the United States of America 1995 Mar 28; 92(7): 2944-8
ARUA - Uelhoff,A.; Tatzelt,J.; Aguzzi,A.; Winklhofer,K.F.; Haass,C. - A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein - The Journal of Biological Chemistry 2005 Feb 18; 280(7): 5137-40
AUJW - Winklhofer,K.F.; Tatzelt,J. - The role of chaperones in Parkinson's disease and prion diseases - Handbook of Experimental Pharmacology 2006(172): 221-58
APAM - Winklhofer,K.F.; Heske,J.; Heller,U.; Tatzelt,J. - Folding of the prion protein in the secretory pathway: implications for the formation of scrapie prions - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-42
ANVP - Winklhofer,K.F.; Heller,U.; Reintjes,A.; Tatzelt,J. - Inhibition of complex glycosylation increases the formation of PrPsc - Traffic (Copenhagen, Denmark) 2003 May; 4(5): 313-22
ANNI - Winklhofer,K.F.; Heske,J.; Heller,U.; Reintjes,A.; Muranyi,W.; Moarefi,I.; Tatzelt,J. - Determinants of the in vivo folding of the prion protein. A bipartite function of helix 1 in folding and aggregation. - The Journal of Biological Chemistry 2003 Apr 25; 278(17): 14961-70
AMQN - Winklhofer,K.F.; Reintjes,A.; Hoener,M.C.; Voellmy,R.; Tatzelt,J. - Geldanamycin restores a defective heat shock response in vivo - The Journal of Biological Chemistry 2001 Nov 30; 276(48): 45160-7
AMQO - Winklhofer,K.F.; Hartl,F.U.; Tatzelt,J. - A sensitive filter retention assay for the detection of PrPsc and the screening of anti-prion compounds - FEBS Letters 2001 Aug 10; 503(1): 41-5
AMQP - Winklhofer,K.F.; Tatzelt,J. - Cationic lipopolyamines induce degradation of PrPsc in scrapie-infected mouse neuroblastoma cells - Biological Chemistry 2000 May-Jun; 381(5-6): 463-9