AXIU - Barnard,G.; Hopkins,L.; Seilly,D.; McConnell,I. - Direct Detection of Disease-Associated Prions in Brain and Lymphoid Tissue Using Antibodies Recognising The Extreme N-Terminus of PrPc - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.172
ABER - Bell,J.D.; Cox,I.J.; Williams,S.C.R.; Belton,P.S.; McConnell,I.; Hope,J. - In vivo detection of metabolic changes in a mouse model of scrapie using nuclear magnetic resonance spectroscopy - Journal of General Virology 1991 Oct; 72(10): 2419-23
AXJO - Bishop,M.; Barron,R.; McConnell,I.; Head,M.; Ironside,J.; Will,R.; Manson,J. - Sporadic CJD Strain Classification by Transmission to Human Transgenic Mice - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Oral Abstracts FC2.3
ABXE - Bruce,M.E.; Boyle,A.; Cousens,S.N.; McConnell,I.; Foster,J.; Goldmann,W.; Fraser,H. - Strain characterization of natural sheep scrapie and comparison with BSE - Journal of General Virology 2002 Mar; 83(3): 695-704
ABXF - Bruce,M.E.; McConnell,I.; Will,R.G.; Ironside,J.W. - Detection of variant Creutzfeldt-Jakob disease infectivity in extraneural tissues - Lancet 2001 Jul 21; 358(9277): 208-9
ABXI - Bruce,M.E.; Will,R.G.; Ironside,J.W.; McConnell,I.; Drummond,D.; Suttie,A.; McCardle,L.; Chree,A.; Hope,J.; Birkett,C.R.; Cousens,S.N.; Fraser,H.; Bostock,C.J. - Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent - Nature 1997 Oct 2; 389(6650): 498-501
ABXD - Bruce,M.E.; Chree,A.; McConnell,I.; Foster,J.; Pearson,G.; Fraser,H. - Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier. - Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 1994 Mar 29; 343(1306): 405-11
ABXL - Bruce,M.E.; McConnell,I.; Fraser,H.; Dickinson,A.G. - The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis. - Journal of General Virology 1991 Mar; 72(3): 595-603
AUCO - Dabaghian,R.H.; Barnard,G.; McConnell,I.; Clewley,J.P. - An immunoassay for the pathological form of the prion protein based on denaturation and time resolved fluorometry - Journal of Virological Methods 2006 Mar; 132(1-2): 85-91
ATCG - Dabaghian,R.H.; Barnard,G.; McConnell,I.; Clewley,J.P. - An immunoassay for the pathological form of the prion protein based on denaturation and time resolved fluorometry - Journal of Virological Methods 2005 Oct 8
AQIS - Davies,M.L.; Hopkins,L.J.; Halliday,S.I.; Houston,E.F.; Hunter,N.; McConnell,I. - Architecture of secondary lymphoid tissue in sheep experimentally challenged with scrapie - Immunology 2004 Feb; 111(2): 230-6
ADIN - Dickinson,A.G.; Fraser,H.; McConnell,I.; Outram,G.W. - Mitogenic stimulation of the host enhances susceptibility to scrapie - Nature 1978 Mar 2; 272(5648): 54-5
ADIK - Dickinson,A.G.; Fraser,H.; McConnell,I.; Outram,G.W.; Sales,D.I.; Taylor,D.M. - Extraneural competition between different scrapie agents leading to loss of infectivity - Nature 1975 Feb 13; 253(5492): 556
AXLY - Farquhar,C.; Cumming,S.; McConnell,I.; Laing,F.; Boyle,A.; Turner,M.L.; Bruce,M.E. - Scrapie Affected Mice Survive Longer with Parenteral Pentosan Polysulphate - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.10
AXLZ - Farquhar,C.F.; Brown,K.L.; McConnell,I.; Boyle,A.; Mabbott,N.A.; Bruce,M.E. - The Immune System Facilitates BSE Transmission into Mice - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Oral Abstracts FC3.7
AWES - Farquhar,C.F.; McConnell,I.; Cumming,S.; Herd,S.; Marshall,A.; Barclay,R.; Pepper,D.S.; Prescott,R.J.; Turner,M.L.; Bruce,M.E. - Sodium pentosan polysulphate use in rodent models of scrapie and BSE - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Oral sessions ORAL-50
AOSH - Farquhar,C.F.; McConnell,I.; Cumming,S.; Boyle,A.; Prescott,R.J.; Turner,M.L.; Bruce,M.E. - Pentosan polysulphate has prophylactic potential for transmissible spongiform encephalopathies - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - IV-09
AECY - Foster,J.D.; Bruce,M.; McConnell,I.; Chree,A.; Fraser,H. - Detection of BSE infectivity in brain and spleen of experimentally infected sheep - The Veterinary Record 1996 Jun 1; 138(22): 546-8
AECZ - Foster,J.D.; Hope,J.; McConnell,I.; Bruce,M.; Fraser,H. - Transmission of bovine spongiform encephalopathy to sheep, goats, and mice - Slow Infections of the Central Nervous System (Ed. Bjornsson,J.; Carp,R.I.; Love,A.; Wisniewski,H.M.) 1994 Jun 6; 724 : 300-3
AEEG - Fraser,H.; Brown,K.L.; Stewart,K.; McConnell,I.; McBride,P.A.; Williams,A. - Replication of scrapie in spleens of SCID mice follows reconstitution with wild-type mouse bone marrow - Journal of General Virology 1996 Aug; 77(8): 1935-40
AEEI - Fraser,H.; Pearson,G.R.; McConnell,I.; Bruce,M.E.; Wyatt,J.M.; Gruffydd-Jones,T.J. - Transmission of feline spongiform encephalopathy to mice - The Veterinary Record 1994 Apr 23; 134(17): 449
AEEK - Fraser,H.; Bruce,M.E.; Chree,A.; McConnell,I.; Wells,G.A.H. - Transmission of bovine spongiform encephalopathy and scrapie to mice - Journal of General Virology 1992 Aug; 73(8): 1891-7
APZJ - Fraser,H.; Bruce,M.E.; McConnell,I. - Murine scrapie strains, BSE models and genetics - Sub-Acute Spongiform Encephalopathies, edited by Ray Bradley, Marc Savey and Brian Marchant - Proceedings of a Seminar in the CEC Agricultural Research Programme, held in Brussels, 12-14 November 1990, 1991; 55: 131-47
AEEM - Fraser,H.; Farquhar,C.F.; McConnell,I.; Davies,D. - The scrapie disease process is unaffected by ionising radiation - Progress in Clinical and Biological Research 1989; 317: 653-8
ANIC - Fraser,H.; McConnell,I.; Wells,G.A.H.; Dawson,M. - Transmission of bovine spongiform encephalopathy to mice - The Veterinary Record 1988 Oct 29; 123(18): 472
AFSU - Hunter,N.; Dann,J.C.; Bennett,A.D.; Somerville,R.A.; McConnell,I.; Hope,J. - Are Sinc and the PrP gene congruent? Evidence from PrP gene analysis in Sinc congenic mice - Journal of General Virology 1992 Oct; 73(10): 2751-5
AFTA - Hunter,N.; Hope,J.; McConnell,I.; Dickinson,A.G. - Linkage of the scrapie-associated fibril protein (PrP) gene and Sinc using congenic mice and restriction fragment length polymorphism analysis - Journal of General Virology 1987 Oct; 68(10): 2711-6
AHBL - Laszlo,L.; Lowe,J.; Self,T.; Kenward,N.; Landon,M.; McBride,P.A.; Farquhar,C.F.; McConnell,I.; Brown,J.M.; Hope,J.; Mayer,R.J. - Lysosomes as key organelles in the pathogenesis of prion encephalopathies - Journal of Pathology 1992 Apr; 166(4): 333-41
ANYP - Mabbott,N.A.; Young,J.; McConnell,I.; Bruce,M.E. - Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility - Journal of Virology 2003 Jun; 77(12): 6845-54
AHTP - Manolakou,K.; Beaton,J.; McConnell,I.; Farquar,C.; Manson,J.; Hastie,N.D.; Bruce,M.E.; Jackson,I.J. - Genetic and environmental factors modify bovine spongiform encephalopathy incubation period in mice - Proceedings of the National Academy of Sciences of the United States of America 2001 Jun 19; 98(13): 7402-7
AHTV - Manson,J.C.; Barron,R.M.; Jamieson,E.; Baybutt,H.N.; Tuzi,N.L.; McConnell,I.; Melton,D.; Hope,J.; Bostock,C.J. - A single amino acid alteration in murine PrP dramatically alters TSE incubation time - Archives of Virology. Supplementum 2000(16): 95-102
AHTX - Manson,J.C.; Jamieson,E.; Baybutt,H.N.; Tuzi,N.L.; Barron,R.M.; McConnell,I.; Somerville,R.; Ironside,J.; Will,R.; Sy,M.S.; Melton,D.W.; Hope,J.; Bostock,C.J. - A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy - EMBO Journal 1999 Dec 1; 18(23): 6855-64
AHTY - Manson,J.C.; Clarke,A.R.; McBride,P.A.; McConnell,I.; Hope,J. - PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology - Neurodegeneration. A Journal for neurodegenerative Disorders, Neuroprotection, and Neuroregeneration 1994 Dec; 3(4): 331-40
AHTZ - Manson,J.C.; Clarke,A.R.; Hooper,M.L.; Aitchison,L.; McConnell,I.; Hope,J. - 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal - Molecular Neurobiology 1994 Apr-Jun; 8(2-3): 121-7
AINS - Moore,R.C.; Hope,J.; McBride,P.A.; McConnell,I.; Selfridge,J.; Melton,D.W.; Manson,J.C. - Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent - Nature Genetics 1998 Feb; 18(2): 118-25
ATAI - Pan,T.; Chang,B.; Wong,P.; Li,C.; Li,R.; Kang,S.C.; Robinson,J.D.; Thompsett,A.R.; Tein,P.; Yin,S.; Barnard,G.; McConnell,I.; Brown,D.R.; Wisniewski,T.; Sy,M.S. - An aggregation-specific enzyme-linked immunosorbent assay: detection of conformational differences between recombinant PrP protein dimers and PrPsc aggregates. - Journal of Virology 2005 Oct; 79(19): 12355-64
AQGL - Smith,P.; Bassett,J.; Brown,D.; Browne,C.; Bulfield,G.; Carrell,R.; Chambers,J.; Hooper,N.; Jinman,P.; Lasmezas,C.I.; McConnell,I.; Manson,J.; Medley,G.; Rudge,P. - Spongiform Encephalopathy Advisory Committee (SEAC) - Minutes of the 81st meeting held on 25th February 2004 - Internet
ALMN - Taylor,D.M.; Fernie,K.; Steele,P.J.; McConnell,I.; Somerville,R.A. - Thermostability of mouse-passaged BSE and scrapie is independent of host PrP genotype: implications for the nature of the causal agents. - Journal of General Virology 2002 Dec; 83(12): 3199-204
ALMT - Taylor,D.M.; McConnell,I.; Ferguson,C.E. - Closely similar values obtained when the ME7 strain of scrapie agent was titrated in parallel by two individuals in separate laboratories using two sublines of C57BL mice - Journal of Virological Methods 2000 Apr; 86(1): 35-40
ALMX - Taylor,D.M.; Fernie,K.; McConnell,I.; Steele,P.J. - Survival of scrapie agent after exposure to sodium dodecyl sulphate and heat - Veterinary Microbiology 1999 Jun 1; 67(1): 13-6
ALMY - Taylor,D.M.; Fernie,K.; McConnell,I.; Steele,P.J. - Observations on thermostable subpopulations of the unconventional agents that cause transmissible degenerative encephalopathies - Veterinary Microbiology 1998 Nov; 64(1): 33-8
ALMZ - Taylor,D.M.; Fernie,K.; McConnell,I.; Ferguson,C.E.; Steele,P.J. - Solvent extraction as an adjunct to rendering: the effect on BSE and scrapie agents of hot solvents followed by dry heat and steam. - The Veterinary Record 1998 Jul 4; 143(1): 6-9
ALNB - Taylor,D.M.; Brown,J.M.; Fernie,K.; McConnell,I. - The effect of formic acid on BSE and scrapie infectivity in fixed and unfixed brain-tissue - Veterinary Microbiology 1997 Nov; 58(2-4): 167-74
ALNC - Taylor,D.M.; Fernie,K.; McConnell,I. - Inactivation of the 22A strain of scrapie agent by autoclaving in sodium hydroxide - Veterinary Microbiology 1997 Nov; 58(2-4): 87-91
ALNE - Taylor,D.M.; McConnell,I.; Fernie,K. - The effect of dry heat on the ME7 strain of mouse-passaged scrapie agent - Journal of General Virology 1996 Dec; 77(12): 3161-4
ALNG - Taylor,D.M.; McConnell,I.; Fraser,H. - Scrapie infection can be established readily through skin scarification in immunocompetent but not immunodeficient mice - Journal of General Virology 1996 Jul; 77(7): 1595-9
ALNH - Taylor,D.M.; McConnell,I. - Unconventional transmissible agents in dura mater: significance for iatrogenic Creutzfeldt-Jakob disease. - Neuropathology and Applied Neurobiology 1996 Jun; 22(3): 259-60
ALNP - Taylor,D.M.; Fraser,H.; McConnell,I.; Brown,D.A.; Brown,K.L.; Lamza,K.A.; Smith,G.R. - Decontamination studies with the agents of bovine spongiform encephalopathy and scrapie - Archives of Virology 1994; 139(3-4): 313-26
ALOF - Taylor,D.M.; McConnell,I. - Autoclaving does not decontaminate formol-fixed scrapie tissues - Lancet 1988 Jun 25; 1(8600): 1463-4
ANVX - McConnell,J. - Still no trend discernible in new-variant CJD incidence, say experts - Lancet 1997 Jul 12; 350(9071): 120