AXMF - Fernie,K.; Smith,A.; Somerville,R. - Environmental Persistence of TSE Infectivity: Field Studies - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Epidemiology, Risk Assessment and Transmission P04.125
AERS - Goldmann,W.; Hunter,N.; Somerville,R.; Hope,J. - Prion phylogeny revisited - Nature 1996 Jul 4; 382(6586): 32-3
AFNG - Hope,J.; Ritchie,L.; Farquhar,C.F.; Somerville,R.; Hunter,N. - Bovine spongiform encephalopathy: a scrapie-like disease of British cattle. - Progress in Clinical and Biological Research 1989; 317: 659-67
AHTX - Manson,J.C.; Jamieson,E.; Baybutt,H.N.; Tuzi,N.L.; Barron,R.M.; McConnell,I.; Somerville,R.; Ironside,J.; Will,R.; Sy,M.S.; Melton,D.W.; Hope,J.; Bostock,C.J. - A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy - EMBO Journal 1999 Dec 1; 18(23): 6855-64
AXWV - Somerville,R. - Diversity in the Biological and Chemical Properties of TSE Agent-Strains: Implications for TSE Agent Structure - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Natural and Experimental Strains P02.34
AQGR - Barr,J.B.; Somerville,R.A.; Chung,Y.L.; Fraser,J.R. - Microdissection: a method developed to investigate mechanisms involved in transmissible spongiform encephalopathy pathogenesis. - BMC Infectious Diseases 2004 Mar 3; 4(1): 8
AWRO - Cooke,C.M.; Rodger,J.; Smith,A.; Fernie,K.; Shaw,G.; Somerville,R.A. - Fate of prions in soil: detergent extraction of PrP from soils. - Environmental Science and Technology 2007 Feb 1; 41(3): 811-7
ACWL - Corp,C.R.; Somerville,R.A. - Nucleic acids associated with detergent-treated synaptosomal plasma membranes from normal and scrapie-infected mouse brain - Biochemical Society Transactions 1976; 4(6): 1110-2
ADWI - Farquhar,C.F.; Somerville,R.A.; Bruce,M.E. - Straining the prion hypothesis - Nature 1998 Jan 22; 391(6665): 345-6
ADWJ - Farquhar,C.F.; Dornan,J.; Moore,R.C.; Somerville,R.A.; Tunstall,A.M.; Hope,J. - Protease-resistant PrP deposition in brain and non-central nervous system tissues of a murine model of bovine spongiform encephalopathy - Journal of General Virology 1996 Aug; 77(8): 1941-6
ADWK - Farquhar,C.F.; Dornan,J.; Somerville,R.A.; Tunstall,A.M.; Hope,J. - Effect of Sinc genotype, agent isolate and route of infection on the accumulation of protease-resistant PrP in non-central nervous system tissues during the development of murine scrapie - Journal of General Virology 1994 Mar; 75(3): 495-504
AUVU - Farquhar,C.F.; Somerville,R.A.; Dornan,J.; Armstrong,D.; Birkett,C.R.; Hope,J. - A review of the detection of PrPsc - Transmissible Spongiform Encephalopathies. A Consultation on BSE with the Scientific Veterinary Committee of the Commission of the European Communities held in Brussels, September 14-15, 1993. Edited by R. Bradley and B. Marchant. European Commission, Agriculture, Document VI/4131/94-EN 1994, pp. 301-313
ADWL - Farquhar,C.F.; Somerville,R.A.; Ritchie,L.A. - Post-mortem immunodiagnosis of scrapie and bovine spongiform encephalopathy - Journal of Virological Methods 1989 Apr-May; 24(1-2): 215-21
AXFF - Fernie,K.; Steele,P.J.; Taylor,D.M.; Somerville,R.A. - Comparative studies on the thermostability of five strains of transmissible-spongiform-encephalopathy agent - Biotechnology and Applied Biochemistry 2007 Aug; 47(4): 175-83
AWET - Fernie,K.; Smith,A.; Cooke,C.M.; Shaw,G.; Rodger,J.; Somerville,R.A. - Assessment of hazards from environmental persistence of TSE infectivity - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions RA-03
AECS - Foster,J.D.; Farquhar,C.F.; Fraser,J.R; Somerville,R.A. - Immunolocalization of the prion protein in scrapie affected rodent retinas - Neuroscience Letters 1999 Jan 22; 260(1): 1-4
AQJL - Foster,P.R.; Griffin,B.D.; Bienek,C.; McIntosh,R.V.; MacGregor,I.R.; Somerville,R.A.; Steele,P.J.; Reichl,H.E. - Distribution of a bovine spongiform encephalopathy-derived agent over ion-exchange chromatography used in the preparation of concentrates of fibrinogen and factor VIII - Vox Sanguinis 2004 Feb; 86(2): 92-9
AXMP - Fujita,Y.; Matsuura,Y.; Ishikawa,Y.; Somerville,R.A.; Kitamoto,T.; Yokoyama,T.; Mohri,S. - Heat Resistance of BSE Infectivity by Dehydration of Materials - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Epidemiology, Risk Assessment and Transmission P04.05
AEOF - Gibson,P.H.; Somerville,R.A.; Fraser,H.; Foster,J.D.; Kimberlin,R.H. - Scrapie associated fibrils in the diagnosis of scrapie in sheep - The Veterinary Record 1987 Feb 7; 120(6): 125-7
AUHN - Grobben,A.H.; Steele,P.J.; Somerville,R.A.; Taylor,D.M. - Inactivation of transmissible spongiform encephalopathy agents during the manufacture of dicalcium phosphate from bone - The Veterinary Record 2006 Mar 18; 158(11): 361-6
AUHO - Grobben,A.H.; Steele,P.J.; Somerville,R.A.; Taylor,D.M. - Inactivation of BSE infectivity on chips of bone by autoclaving during the manufacture of gelatine - The Veterinary Record 2006 Jan 21; 158(3): 94-6
ASWW - Grobben,A.H.; Steele,P.J.; Somerville,R.A.; Taylor,D.M.; Schreuder,B.E.C. - Inactivation of the BSE agent by the heat and pressure process for manufacturing gelatine - The Veterinary Record 2005 Sep 3; 157(10): 277-81
APHO - Grobben,A.H.; Steele,P.J.; Somerville,R.A.; Taylor,D.M. - Inactivation of the bovine-spongiform-encephalopathy (BSE) agent by the acid and alkaline processes used in the manufacture of bone gelatine - Biotechnology and Applied Biochemistry 2004 Jun; 39(3): 329-38
AFSU - Hunter,N.; Dann,J.C.; Bennett,A.D.; Somerville,R.A.; McConnell,I.; Hope,J. - Are Sinc and the PrP gene congruent? Evidence from PrP gene analysis in Sinc congenic mice - Journal of General Virology 1992 Oct; 73(10): 2751-5
AFUY - Iqbal,K.; Somerville,R.A.; Thompson,C.H.; Wisniewski,H.M. - Brain glutamate decarboxylase and cholinergic enzyme activities in scrapie - Journal of the Neurological Sciences 1985 Mar; 67(3): 345-50
AVLD - Kirchmayr,R.; Reichl,H.E.; Schildorfer,H.; Braun,R.; Somerville,R.A. - Prion protein: detection in 'spiked' anaerobic sludge and degradation experiments under anaerobic conditions. - Water Science and Technology 2006; 53(8): 91-8
AHOA - Lowe,J.; McDermott,H.; Kenward,N.; Landon,M.; Mayer,R.J.; Bruce,M.E.; McBride,P.A.; Somerville,R.A.; Hope,J. - Ubiquitin conjugate immunoreactivity in the brains of scrapie infected mice - Journal of Pathology 1990 Sep; 162(1): 61-6
AIHM - Merz,P.A.; Rohwer,R.G.; Kascsak,R.; Wisniewski,H.M.; Somerville,R.A.; Gibbs,C.J.Jr.; Gajdusek,D.C. - Infection-specific particle from the unconventional slow virus diseases - Science 1984 Jul 27; 225(4660): 437-40
AIHN - Merz,P.A.; Somerville,R.A.; Wisniewski,H.M.; Manuelidis,L.; Manuelidis,E.E. - Scrapie-associated fibrils in Creutzfeldt-Jakob disease - Nature 1983 Dec 1-7; 306(5942): 474-6
AIHO - Merz,P.A.; Wisniewski,H.M.; Somerville,R.A.; Bobin,S.A.; Masters,C.L.; Iqbal,K. - Ultrastructural morphology of amyloid fibrils from neuritic and amyloid plaques - Acta Neuropathologica 1983; 60(1-2): 113-24
AIHP - Merz,P.A.; Somerville,R.A.; Wisniewski,H.M.; Iqbal,K. - Abnormal fibrils from scrapie-infected brain - Acta Neuropathologica 1981; 54(1): 63-74
AIMQ - Mohri,S.; Farquhar,C.F.; Somerville,R.A.; Jeffrey,M.J.; Foster,J.; Hope,J. - Immunodetection of a disease specific PrP fraction in scrapie-affected sheep and BSE-affected cattle - The Veterinary Record 1992 Dec 5; 131(23): 537-9
AJTY - Quinn,M.R.; Somerville,R.A. - Decreased high-affinity binding of [3H]muscimol to cerebral synaptic membranes of scrapie-infected mice - Journal of Neurochemistry 1984 Jan; 42(1): 290-3
AJXF - Reichl,H.E.; Foster,P.R.; Welch,A.G.; Li,Q.; MacGregor,I.R.; Somerville,R.A.; Fernie,K.; Steele,P.J.; Taylor,D.M. - Studies on the removal of a bovine spongiform encephalopathy-derived agent by processes used in the manufacture of human immunoglobulin - Vox Sanguinis 2002 Aug; 83(2): 137-45
AOYI - Rodger,J.M.; Somerville,R.A. - Persistence of TSEs in the Environment - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - IV-17
ANZH - Schreuder,B.E.C.; Somerville,R.A. - Bovine spongiform encephalopathy in sheep? - Revue Scientifique et Technique de l'Office International des Epizooties 2003 Apr; 22(1): 103-20
AXWP - Smith,A.J.; Fernie,K.; Somerville,R.A. - Environmental Persistence of TSEs - Extraction of PrPsc from Soil - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Epidemiology, Risk Assessment and Transmission P04.08
AWOB - Somerville,R.A.; Gentles,N.; Fernie,K. - Characterization of the effect of heat on TSE agent-strains - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions S-24
ATFV - Somerville,R.A.; Fernie,K.; Gentles,N. - Heat inactivation properties of TSE strains - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Oral sessions ORAL-26
ARTM - Somerville,R.A.; Hamilton,S.; Fernie,K. - Transmissible spongiform encephalopathy strain, PrP genotype and brain region all affect the degree of glycosylation of PrPsc - Journal of General Virology 2005 Jan; 86(1): 241-6
AOZH - Somerville,R.A.; Fernie,K.; Steele,P.J.; Hamilton,S.; Gentles,N. - Do the properties of TSE agents and PrPsc differ? - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-121
ALAE - Somerville,R.A. - TSE agent strains and PrP: reconciling structure and function. - Trends in Biochemical Sciences 2002 Dec; 27(12): 606-12
ALAF - Somerville,R.A.; Oberthür,R.C.; Havekost,U.; MacDonald,F.; Taylor,D.M.; Dickinson,A.G. - Characterization of thermodynamic diversity between transmissible spongiform encephalopathy agent strains and its theoretical implications - The Journal of Biological Chemistry 2002 Mar 29; 277(13): 11084-9
ALAG - Somerville,R.A. - Is there more to TSE diseases than PrP? - Trends in Microbiology 2000 Apr; 8(4): 157-8
ALAH - Somerville,R.A. - Host and transmissible spongiform encephalopathy agent strain control glycosylation of PrP - Journal of General Virology 1999 Jul; 80(7): 1865-72
ALAI - Somerville,R.A.; Birkett,C.R.; Farquhar,C.F.; Hunter,N.; Goldmann,W.; Dornan,J.; Grover,D.; Hennion,R.M.; Percy,C.; Foster,J.; Jeffrey,M.J. - Immunodetection of PrPsc in spleens of some scrapie-infected sheep but not BSE-infected cows - Journal of General Virology 1997 Sep; 78(9): 2389-96
ALAJ - Somerville,R.A.; Chong,A.; Mulqueen,O.U.; Birkett,C.R.; Wood,S.C.E.R.; Hope,J. - Biochemical typing of scrapie strains - Nature 1997 Apr 10; 386(6625): 564
ALAK - Somerville,R.A.; Dunn,A.J. - The association between PrP and infectivity in scrapie and BSE infected mouse brain - Archives of Virology 1996; 141(2): 275-89
AUWD - Somerville,R.A. - Diagnosis and agent structure: a discussion - Transmissible Spongiform Encephalopathies. A Consultation on BSE with the Scientific Veterinary Committee of the Commission of the European Communities held in Brussels, September 14-15, 1993. Edited by R. Bradley and B. Marchant. European Commission, Agriculture, Document VI/4131/94-EN 1994, pp. 443-449
ALAL - Somerville,R.A.; Ritchie,L.A. - Differential glycosylation of the protein (PrP) forming scrapie-associated fibrils - Journal of General Virology 1990 Apr; 71(4): 833-9
ALAM - Somerville,R.A.; Ritchie,L.A.; Gibson,P.H. - Structural and biochemical evidence that scrapie-associated fibrils assemble in vivo - Journal of General Virology 1989 Jan; 70(1): 25-35
ALAN - Somerville,R.A.; Merz,P.A.; Carp,R.I. - Partial copurification of scrapie-associated fibrils and scrapie infectivity - Intervirology 1986; 25(1): 48-55
ALAO - Somerville,R.A. - Ultrastructural links between scrapie and Alzheimer's disease - Lancet 1985 Mar 2; 1(8427): 504-6
ALAP - Somerville,R.A.; Carp,R.I. - Altered scrapie infectivity estimates by titration and incubation period in the presence of detergents - Journal of General Virology 1983 Sep; 64 (9): 2045-50
ALAQ - Somerville,R.A.; Millson,G.C.; Kimberlin,R.H. - Sensitivity of scrapie infectivity to detergents and 2-mercaptoethanol - Intervirology 1980; 13(2): 126-9
ALAR - Somerville,R.A.; Millson,G.C.; Hunter,G.D. - Changes in a protein-nucleic acid complex from synaptic plasma membrane of scrapie-infected mouse brain - Biochemical Society Transactions 1976; 4(6): 1112-4
ALMN - Taylor,D.M.; Fernie,K.; Steele,P.J.; McConnell,I.; Somerville,R.A. - Thermostability of mouse-passaged BSE and scrapie is independent of host PrP genotype: implications for the nature of the causal agents. - Journal of General Virology 2002 Dec; 83(12): 3199-204
ALMQ - Taylor,D.M.; Fernie,K.; Steele,P.J.; Somerville,R.A. - Relative efficiency of transmitting bovine spongiform encephalopathy to RIII mice by the oral route - The Veterinary Record 2001 Mar 17; 148(11): 345-6
ALMR - Taylor,D.M.; Fernie,K.; Reichl,H.E.; Somerville,R.A. - Infectivity in the blood of mice with a BSE-derived agent - The Journal of Hospital Infection 2000 Sep; 46(1): 78-9