ASWC - Bieler,S.; Estrada,L.; Lagos,R.; Baeza,M.; Castilla,J.; Soto,C. - Amyloid formation modulates the biological activity of a bacterial protein - The Journal of Biological Chemistry 2005 Jul 22; 280(29): 26880-5
AXAF - Brun,A.; Gutierrez-Adan,A.; Castilla,J.; Pintado,B.; Diaz-San Segundo,F.; Cano,M.J.; Alamillo,E.; Espinosa,J.C.; Torres,J.M. - Reduced susceptibility to bovine spongiform encephalopathy prions in transgenic mice expressing a bovine PrP with five octapeptide repeats - Journal of General Virology 2007 Jun; 88(6): 1842-9
APUE - Brun,A.; Castilla,J.; Ramirez,M.A.; Prager,K.; Parra,B.; Salguero,F.J.; Shiveral,D.; Sanchez,C.; Sanchez-Vizcaino,J.M.; Douglas,A.; Torres,J.M. - Proteinase K enhanced immunoreactivity of the prion protein-specific monoclonal antibody 2A11 - Neuroscience Research 2004 Jan; 48(1): 75-83
APFS - Brun,A.; Castilla,J.; Parra,B.; Rodriguez,F.; Torres,J.M. - [Involvement of the immunological system in the pathogenesis of transmissible spongiform encephalopathies] - Implicacion del sistema inmunologico en la patogenesis de las encefalopatias espongiformes transmisibles - Revista de Neurologia 2003 Oct 1-15; 37(7): 648-53
ABYK - Brun,A.; Castilla,J.; Torres,J.M. - [Transmissible spongiform encephalopathies in animals] - Encefalopatias espongiformes transmisibles en animales - Revista de Neurologia 2000 Jul 16-31; 31(2): 133-7
ASSG - Brun,A.; Castilla,J.; Torres,J.M. - Encefalopatias espongiformes transmisibles en animales - First Ibero-american Virtual Neurology Congress 15.10.-30.11.1998
AXKH - Castilla,J.; Nonno,R.; Fernandez-Borges,N.; Di Bari,M.A.; Cosseddu,G.M.; de Castro,J.; Chiappini,B.; Vaccari,G.; Agrimi,U. - De Novo Generation of Prions in a Cell-free System - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Oral Abstracts FC7.4
AVIO - Castilla,J.; Saa,P.; Morales,R.; Abid,K.; Maundrell,K.; Soto,C. - Protein misfolding cyclic amplification for diagnosis and prion propagation studies - Methods in Enzymology 2006; 412: 3-21
ATST - Castilla,J.; Gutierrez-Adan,A.; Brun,A.; Pintado,B.; Salguero,F.J.; Parra,B.; Segundo,F.D.S.; Ramirez,M.A.; Rabano,A.; Cano,M.J.; Torres,J.M. - Transgenic mice expressing bovine PrP with a four extra repeat octapeptide insert mutation show a spontaneous, non-transmissible, neurodegenerative disease and an expedited course of BSE infection - FEBS Letters 2005 Nov 7; 579(27): 6237-46
ASVQ - Castilla,J.; Saa,P.; Soto,C. - Detection of prions in blood - Nature Medicine 2005 Sep; 11(9): 982-5
ASLX - Castilla,J.; Brun,A.; Diaz San Segundo,F.; Salguero,F.J.; Gutierrez-Adan,A.; Pintado,B.; Ramirez,M.A.; del Riego,L.; Torres,J.M. - Vertical transmission of bovine spongiform encephalopathy prions evaluated in a transgenic mouse model - Journal of Virology 2005 Jul; 79(13): 8665-8
ASIV - Castilla,J.; Saa,P.; Hetz,C.A.; Soto,C. - In vitro generation of infectious scrapie prions - Cell 2005 Apr 22; 121(2): 195-206
ARGG - Castilla,J.; Hetz,C.A.; Soto,C. - Molecular mechanisms of neurotoxicity of pathological prion protein - Current Molecular Medicine 2004 Jun; 4(4): 397-403
AQSJ - Castilla,J.; Gutierrez-Adan,A.; Brun,A.; Doyle,D.; Pintado,B.; Ramirez,M.A.; Salguero,F.J.; Parra,B.; Diaz San Segundo,F.; Sanchez-Vizcaino,J.M.; Rogers,M.; Torres,J.M. - Subclinical bovine spongiform encephalopathy infection in transgenic mice expressing porcine prion protein - Journal of Neuroscience 2004 May 26; 24(21): 5063-9
AQHC - Castilla,J.; Gutierrez-Adan,A.; Brun,A.; Pintado,B.; Parra,B.; Ramirez,M.A.; Salguero,F.J.; Diaz San Segundo,F.; Rabano,A.; Cano,M.J.; Torres,J.M. - Different behavior toward bovine spongiform encephalopathy infection of bovine prion protein transgenic mice with one extra repeat octapeptide insert mutation - Journal of Neuroscience 2004 Mar 3; 24(9): 2156-64
AORF - Castilla,J.; Gutierrez,A.; Pintado,B.; Brun,A.; Doyle,D.; Salguero,F.J.; Diaz San Segundo,F.; Parra,B.; Espinosa,J.C.; Rogers,M.; Sanchez-Vizcaino,J.M.; Torres,J.M. - Prion transmission to transgenic mice expressing porcine PrPc - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-90
ANPN - Castilla,J.; Gutierrez Adan,A.; Brun,A.; Pintado,B.; Ramirez,M.A.; Parra,B.; Doyle,D.; Rogers,M.; Salguero,F.J.; Sanchez,C.; Sanchez-Vizcaino,J.M.; Torres,J.M. - Early detection of PrPres in BSE-infected bovine PrP transgenic mice - Archives of Virology 2003 Mar; 148(4): 677-91
AWWH - Espinosa,J.C.; Morales,M.; Castilla,J.; Rogers,M.; Torres,J.M. - Progression of prion infectivity in asymptomatic cattle after oral bovine spongiform encephalopathy challenge - Journal of General Virology 2007 Apr; 88(4): 1379-83
AVJL - Espinosa,J.C.; Andreoletti,O.; Castilla,J.; Herva,M.E.; Morales,M.; Alamillo,E.; San-Segundo,F.D.; Lacroux,C.; Lugan,S.; Salguero,F.J.; Langeveld,J.P.M.; Torres,J.M. - Sheep-passaged bovine spongiform encephalopathy agent exhibits altered pathobiological properties in bovine-PrP transgenic mice - Journal of Virology 2007 Jan; 81(2): 835-43
AWEO - Espinosa,J.C.; Andreoletti,O.; Castilla,J.; Herva,M.E.; Morales,M.; Alamillo,E.; Lacroux,C.; Lugan,S.; Langeveld,J.; Torres,J.M. - Sheep-passaged BSE analysed in BoPrP-Tg110 mice exhibits BSE strain features and accelerated disease course allowing their discrimination from scrapie - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PR-11
ATMH - Espinosa,J.C.; Castilla,J.; Andreoletti,O.; Parra,B.; Cano,M.J.; Diaz San Segundo,F.; Salguero,F.J.; Morales,M.; Torres,J.M. - Transmission barrier in Bovine PrP-Tg mice is strain dependent but independent on the PrP amino acid sequence of the inoculated PrPsc - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Genetics, strains and emerging problems GEN-07
AXNH - Gonzalez-Romero,D.; Castilla,J.; Morales,R.; Soto,C. - Crossing Species Barrier in Vitro by PMCA - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Natural and Experimental Strains P02.21
AXNM - Green,K.M.; Castilla,J.; Seward,T.S.; Soto,C.; Telling,G.C. - Accelerated Sudies of Interspecies Prion Transmission Using Combined Transgenic and PMCA Technologies - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Oral Abstracts FC2.7
AXAM - Hetz,C.A.; Castilla,J.; Soto,C. - Perturbation of endoplasmic reticulum homeostasis facilitates prion replication - The Journal of Biological Chemistry 2007 Apr 27; 282(17): 12725-33
AUAR - Hetz,C.A.; Russelakis-Carneiro,M.; Walchli,S.; Carboni,S.; Vial-Knecht,E.; Maundrell,K.; Castilla,J.; Soto,C. - The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity - Journal of Neuroscience 2005 Mar 16; 25(11): 2793-802
APHX - Hetz,C.A.; Russelakis-Carneiro,M.; Maundrell,K.; Castilla,J.; Soto,C. - Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein - EMBO Journal 2003 Oct 15; 22(20): 5435-45
AWHF - Huelamo,T.; Parra,B.; Castilla,J.; Nevado,M.J.; Anadon,E.; Soto,C.; Gomez-Tejedor,C.; Mayoral,T. - Highly increasing of sensitivity in scrapie detection by rapid tests using PMCA - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions DIA-27
AXAT - Martin,S.F.; Buron,I.; Espinosa,J.C.; Castilla,J.; Villalba,J.M.; Torres,J.M. - Coenzyme Q and protein/lipid oxidation in a BSE-infected transgenic mouse model - Free Radical Biology and Medicine 2007 Jun 1; 42(11): 1723-9
AUZH - Martin,S.F.; Herva,M.E.; Espinosa,J.C.; Parra,B.; Castilla,J.; Brun,A.; Torres,J.M. - Cell expression of a four extra octarepeat mutated PrPc modifies cell structure and cell cycle regulation - FEBS Letters 2006 Jul 24; 580(17): 4097-104
ATNJ - Martin,S.F.; Castilla,J.; Brun,A.; Salguero,F.J.; Villalba,J.M.; Torres,J.M. - CoQ and protein/lipid oxidation in BSE inoculated Bo-PrP-Tg Mice - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Human prions, risk of blood products, and therapy HUMAN-07
ATLI - Mayoral,T.; Huelamo,T.; Castilla,J.; Nevado,M.J.; Saa,P.; del Valle Perez-Barbachano,M.; Soto,C.; Gomez-Tejedor,C. - Protein Misfolding Cyclic Amplification (PMCA) vs BSE and Scrapie diagnosis. - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Diagnosis DIA-46
AXSX - Morales,R.; Castilla,J.; Saa,P.; Soto,C. - In Vitro Prion Propagation of Prion Strains - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Oral Abstracts FC2.2
AXSY - Morales,R.; Estrada,L.; Castilla,J.; Soto,C. - Pathological Interaction Between Protein Misfolding Disorders: Prions and Alzheimer's Disease - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Protein Misfolding P01.34
AWKP - Morales,R.; Castilla,J.; Saa,P.; Soto,C. - In vitro propagation of prion strains - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PR-24
AVYJ - Richt,J.A.; Kasinathan,P.; Hamir,A.N.; Castilla,J.; Sathiyaseelan,T.; Vargas,F.; Sathiyaseelan,J.; Wu,H.; Matsushita,H.; Koster,J.; Kato,S.; Ishida,I.; Soto,C.; Robl,J.M.; Kuroiwa,Y. - Production of cattle lacking prion protein - Nature Biotechnology 2007 Jan; 25(1): 132-8
AVQD - Richt,J.A.; Kasinathan,P.; Hamir,A.N.; Castilla,J.; Sathiyaseelan,T.; Vargas,F.; Sathiyaseelan,J.; Wu,H.; Matsushita,H.; Koster,J.; Kato,S.; Ishida,I.; Soto,C.; Robl,J.M.; Kuroiwa,Y. - Production of cattle lacking prion protein - Nature Biotechnology 2006 Dec 31
AXVE - Rincon-Limas,D.; Casas-Tinto,S.; Nino-Rosales,M.L.; Gomez-Velazquez,M.; Castilla,J.; Soto,C.; Fernandez-Funez,P. - Hsp70 Prevents PrP Misfolding and Protects Drosophila Neurons against PrP Neurotoxicity - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Oral Abstracts FC4.7
AVRN - Saa,P.; Castilla,J.; Soto,C. - Ultra-efficient replication of infectious prions by automated protein misfolding cyclic amplification - The Journal of Biological Chemistry 2006 Nov 17; 281(46): 35245-52
AUUN - Saa,P.; Castilla,J.; Soto,C. - Presymptomatic detection of prions in blood - Science 2006 Jul 7; 313(5783): 92-4
ATGS - Saa,P.; Castilla,J.; Soto,C. - Prion Detection in Blood by PCMA - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Oral sessions ORAL-49
ASRC - Saa,P.; Castilla,J.; Soto,C. - Cyclic amplification of protein misfolding and aggregation - Methods in Molecular Biology 2005; 299: 53-65
AWOD - Soto,C.; Castilla,J.; Morales,R.; Saa,P. - Biochemical detection of prions in blood - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Oral sessions ORAL-44
AUIV - Soto,C.; Estrada,L.; Castilla,J. - Amyloids, prions and the inherent infectious nature of misfolded protein aggregates - Trends in Biochemical Sciences 2006 Mar; 31(3): 150-5
ARNH - Soto,C.; Anderes,L.; Suardi,S.; Cardone,F.; Castilla,J.; Frossard,M.J.; Peano,S.; Saa,P.; Limido,L.; Carbonatto,M.; Ironside,J.; Torres,J.M.; Pocchiari,M.; Tagliavini,F. - Pre-symptomatic detection of prions by cyclic amplification of protein misfolding - FEBS Letters 2005 Jan 31; 579(3): 638-42
AQWO - Soto,C.; Castilla,J. - The controversial protein-only hypothesis of prion propagation - Nature Medicine 2004 Jul; 10 Suppl: S63-7
AWQP - Wiseman,F.; Cancellotti,E.; Castilla,J.; Tuzi,N.L.; Baybutt,H.N.; Aitchison,L.; Ironside,J.; Soto,C.; Manson,J. - Glycosylation of PrP and the transmissible spongiform encephalopathies species barrier - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PA-59