APBC - Aguzzi,A.; Barbara,J.A.J.; Brown,P.; Budka,H.; Diringer,H.; Dormont,D.; Flanagan,P.; Heeschen,W.; Hope,J.; Hörnlimann,B.; Kenney,K.; Masters,C.; Macnaughton,M.R.; Pocchiari,M.; Rohwer,R.G.; Safar,J.G.; Somogyi,A.; Tateishi,J.; Taylor,D.M.; van Duijn,C.M.; Wilesmith,J.W.; Will,R.G.; Wisher,M.H.; Asher,D.M.; de Pedro Cuesta,J.; Feek,C.; Hasebe,K.; Horaud,F.; Löwer,J.; Minor,P.D.; Nandapalan,P.; Pavlov,A.; Perez,A.C.; Ricketts,M.N.; Vicari,G.; van Aken,W.G.; Beal,R.; Menache-Aronson,D.; Bradley,R.; Bailey,A.C.; Chalumeau,H.P.; Garland,A.; Brooks,W.; Schrieber,R.; Sprengers,E.; Andjaparidze,A.G.; Bolis,C.L.; Emmanuel,J.C.; Griffiths,E.; Heymann,D.L.; Kaboyo,W.; Meslin,F.X.; Miyagawa,S.; Padilla Marroquin,A.; Schudel,A.; Zeidler,M. - Medicinal and other products and human and animal transmissible spongiform encephalopathies - memorandum from a WHO meeting - Bulletin of the World Health Organization 1997; 75(N6): 505-13
AATJ - Arnold,J.E.; Tipler,C.; Laszlo,L.; Hope,J.; Landon,M.; Mayer,R.J. - The abnormal isoform of the prion protein accumulates in late-endosome-like organelles in scrapie-infected mouse brain - Journal of Pathology 1995 Aug; 176(4): 403-11
AAZD - Barclay,G.R.; Hope,J.; Birkett,C.R.; Turner,M.L. - Distribution of cell-associated prion protein in normal adult blood determined by flow cytometry - British Journal of Haematology 1999 Dec; 107(4): 804-14
ABER - Bell,J.D.; Cox,I.J.; Williams,S.C.R.; Belton,P.S.; McConnell,I.; Hope,J. - In vivo detection of metabolic changes in a mouse model of scrapie using nuclear magnetic resonance spectroscopy - Journal of General Virology 1991 Oct; 72(10): 2419-23
ARFV - Blanch,E.W.; Gill,A.C.; Rhie,A.G.; Hope,J.; Hecht,L.; Nielsen,K.; Barron,L.D. - Raman optical activity demonstrates poly(L-proline) II helix in the N-terminal region of the ovine prion protein: implications for function and misfunction. - Journal of Molecular Biology 2004 Oct 15; 343(2): 467-76
ABXI - Bruce,M.E.; Will,R.G.; Ironside,J.W.; McConnell,I.; Drummond,D.; Suttie,A.; McCardle,L.; Chree,A.; Hope,J.; Birkett,C.R.; Cousens,S.N.; Fraser,H.; Bostock,C.J. - Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent - Nature 1997 Oct 2; 389(6650): 498-501
ACLN - Chabry,J.; Priola,S.A.; Wehrly,K.; Nishio,J.; Hope,J.; Chesebro,B. - Species-independent inhibition of abnormal prion protein (PrP) formation by a peptide containing a conserved PrP sequence - Journal of Virology 1999 Aug; 73(8): 6245-50
ACQD - Chung,Y.L.; Williams,A.; Ritchie,D.; Williams,S.C.R.; Changani,K.K.; Hope,J.; Bell,J.D. - Conflicting MRI signals from gliosis and neuronal vacuolation in prion diseases - Neuroreport 1999 Nov 26; 10(17): 3471-7
ACQE - Chung,Y.L.; Williams,S.C.R.; Hope,J.; Bell,J.D. - Brain bioenergetics in murine models of scrapie using in vivo 31P magnetic resonance spectroscopy - Neuroreport 1999 Jun 23; 10(9): 1899-901
ACQF - Chung,Y.L.; Williams,A.; Chong,A.; Hope,J.; Williams,S.C.R.; Bell,J.D. - Metabolic changes associated with vacuolation in murine models of scrapie using in vitro 1H-NMR spectroscopy - NMR in Biomedicine 1996 Dec; 9(8): 359-63
ACQG - Chung,Y.L.; Williams,A.; Beech,J.S.; Williams,S.C.R.; Bell,J.D.; Cox,I.J.; Hope,J. - MRI assessment of the blood-brain barrier in a hamster model of scrapie - Neurodegeneration. A Journal for neurodegenerative Disorders, Neuroprotection, and Neuroregeneration 1995 Jun; 4(2): 203-7
AVAQ - Everest,S.J.; Thorne,L.T.; Hawthorn,J.A.; Jenkins,R.; Hammersley,C.; Ramsay,A.M.; Hawkins,S.A.C.; Venables,L.; Flynn,L.; Sayers,R.; Kilpatrick,J.; Sach,A.; Hope,J.; Jackman,R. - No abnormal prion protein detected in the milk of cattle infected with the bovine spongiform encephalopathy agent - Journal of General Virology 2006 Aug; 87(8): 2433-41
AUAB - Everest,S.J.; Thorne,L.; Barnicle,D.A.; Edwards,J.C.; Elliott,H.; Jackman,R.; Hope,J. - Atypical prion protein in sheep brain collected during the British scrapie-surveillance programme - Journal of General Virology 2006 Feb; 87(2): 471-7
ADWJ - Farquhar,C.F.; Dornan,J.; Moore,R.C.; Somerville,R.A.; Tunstall,A.M.; Hope,J. - Protease-resistant PrP deposition in brain and non-central nervous system tissues of a murine model of bovine spongiform encephalopathy - Journal of General Virology 1996 Aug; 77(8): 1941-6
ADWK - Farquhar,C.F.; Dornan,J.; Somerville,R.A.; Tunstall,A.M.; Hope,J. - Effect of Sinc genotype, agent isolate and route of infection on the accumulation of protease-resistant PrP in non-central nervous system tissues during the development of murine scrapie - Journal of General Virology 1994 Mar; 75(3): 495-504
AUVU - Farquhar,C.F.; Somerville,R.A.; Dornan,J.; Armstrong,D.; Birkett,C.R.; Hope,J. - A review of the detection of PrPsc - Transmissible Spongiform Encephalopathies. A Consultation on BSE with the Scientific Veterinary Committee of the Commission of the European Communities held in Brussels, September 14-15, 1993. Edited by R. Bradley and B. Marchant. European Commission, Agriculture, Document VI/4131/94-EN 1994, pp. 301-313
AECX - Foster,J.D.; Hunter,N.; Williams,A.; Mylne,M.J.A.; McKelvey,W.A.C.; Hope,J.; Fraser,H.; Bostock,C.J. - Observations on the transmission of scrapie in experiments using embryo transfer - The Veterinary Record 1996 Jun 8; 138(23): 559-62
AECZ - Foster,J.D.; Hope,J.; McConnell,I.; Bruce,M.; Fraser,H. - Transmission of bovine spongiform encephalopathy to sheep, goats, and mice - Slow Infections of the Central Nervous System (Ed. Bjornsson,J.; Carp,R.I.; Love,A.; Wisniewski,H.M.) 1994 Jun 6; 724 : 300-3
AUVQ - Foster,J.D.; McKelvey,W.A.C.; Mylne,M.J.A.; Williams,A.; Hunter,N.; Hope,J.; Fraser,H. - Studies on vertical transmission of scrapie in sheep and BSE in goats using embryo transfer - Transmissible Spongiform Encephalopathies. A Consultation on BSE with the Scientific Veterinary Committee of the Commission of the European Communities held in Brussels, September 14-15, 1993. Edited by R. Bradley and B. Marchant. European Commission, Agriculture, Document VI/4131/94-EN 1994, pp. 229-237
AEDA - Foster,J.D.; Hope,J.; Fraser,H. - Transmission of bovine spongiform encephalopathy to sheep and goats - The Veterinary Record 1993 Oct 2; 133(14): 339-41
AEDB - Foster,J.D.; McKelvey,W.A.C.; Mylne,M.J.A.; Williams,A.; Hunter,N.; Hope,J.; Fraser,H. - Studies on maternal transmission of scrapie in sheep by embryo transfer - The Veterinary Record 1992 Apr 18; 130(16): 341-3
AOTD - Gill,A.C.; Ritchie,M.A.; Hope,J.; Blanch,E.W.; Hecht,L.; Barron,L.D. - Structure and Function of the N-terminus of PrP - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-103
AEOW - Gill,A.C.; Ritchie,M.A.; Hunt,L.G.; Steane,S.E.; Davies,K.G.; Bocking,S.P.; Rhie,A.G.; Bennett,A.D.; Hope,J. - Post-translational hydroxylation at the N-terminus of the prion protein reveals presence of PPII structure in vivo - EMBO Journal 2000 Oct 16; 19(20): 5324-31
AERQ - Goldmann,W.; Chong,A.; Foster,J.; Hope,J.; Hunter,N. - The shortest known prion protein gene allele occurs in goats, has only three octapeptide repeats and is non-pathogenic - Journal of General Virology 1998 Dec; 79(12): 3173-6
AERS - Goldmann,W.; Hunter,N.; Somerville,R.; Hope,J. - Prion phylogeny revisited - Nature 1996 Jul 4; 382(6586): 32-3
AERT - Goldmann,W.; Hunter,N.; Smith,G.; Foster,J.; Hope,J. - PrP genotypes and the Sip gene in Cheviot sheep form the basis for scrapie strain typing in sheep - Slow Infections of the Central Nervous System (Ed. Bjornsson, J.; Carp, R.I.; Love, A.; Wisniewski, H.M.) 1994 Jun 6; 724: 296-9
AERU - Goldmann,W.; Hunter,N.; Smith,G.; Foster,J.; Hope,J. - PrP genotype and agent effects in scrapie: change in allelic interaction with different isolates of agent in sheep, a natural host of scrapie. - Journal of General Virology 1994 May; 75(5): 989-95
AERW - Goldmann,W.; Hunter,N.; Benson,G.; Foster,J.D.; Hope,J. - Different scrapie-associated fibril proteins (PrP) are encoded by lines of sheep selected for different alleles of the Sip gene - Journal of General Virology 1991 Oct; 72(10): 2411-7
AERX - Goldmann,W.; Hunter,N.; Martin,T.; Dawson,M.; Hope,J. - Different forms of the bovine PrP gene have five or six copies of a short, G-C-rich element within the protein-coding exon - Journal of General Virology 1991 Jan; 72(1): 201-4
AERY - Goldmann,W.; Hunter,N.; Foster,J.D.; Salbaum,J.M.; Beyreuther,K.; Hope,J. - Two alleles of a neural protein gene linked to scrapie in sheep - Proceedings of the National Academy of Sciences of the United States of America 1990 Apr; 87(7): 2476-80
AXNP - Griffiths,P.C.; Spiropoulos,J.; Lockey,R.; Tout,A.C.; Jayasena,D.; Simonini,S.; Dexter,I.; Beringue,V.; Le Dur,A.; Laude,H.; Hope,J. - Bioassay of Atypical Scrapie Cases from Great Britain in TG338 Mice Provides Evidence That They Are Indistinguishable from NOR98 - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Natural and Experimental Strains P02.10
AWGC - Griffiths,P.C.; Spiropoulos,J.; Lockey,R.; Thorne,L.; Jayasena,D.; Jenkins,R.; Plater,J.M.; Tout,A.C.; Green,R.B.; Windl,O.; Beringue,V.; Le Dur,A.; Laude,H.; Buschmann,A.; Groschup,M.H.; Hope,J. - Transmissibility and characterisation of atypical scrapie in mice - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PR-17
AXNX - Hamilton,S.; Dagleish,M.P.; Gonzalez,L.; Siso,S.; Hope,J.; Reid,H.W.; Pang,Y.; Eaton,S.L.; Finlayson,J.; Steele,P.J.; Chianini,F.; Jeffrey,M. - Degradation of Abnormal PrP in Isolated Gut Loops of Sheep Challenged with Scrapie or BSE - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.84
AFMU - Hope,J. - Prions and neurodegenerative diseases - Current Opinion in Genetics and Development 2000 Oct; 10(5): 568-74
AFMV - Hope,J. - Hunting for prions in cyprus-important needles in the TSE haystack - Veterinary Journal 2000 May; 159(3): 213-4
AFMW - Hope,J.; Wood,S.C.E.R.; Birkett,C.R.; Chong,A.; Bruce,M.E.; Cairns,D.; Goldmann,W.; Hunter,N.; Bostock,C.J. - Molecular analysis of ovine prion protein identifies similarities between BSE and an experimental isolate of natural scrapie, CH1641 - Journal of General Virology 2000 Mar; 81(3): 851
AFMX - Hope,J. - Spongiform encephalopathies. Breech-birth prions. - Nature 1999 Dec 16; 402(6763): 737, 739
AFMY - Hope,J. - Prions - Current Biology 1999 Sep 23; 9(18): R673-4
AFMZ - Hope,J.; Wood,S.C.E.R.; Birkett,C.R.; Chong,A.; Bruce,M.E.; Cairns,D.; Goldmann,W.; Hunter,N.; Bostock,C.J. - Molecular analysis of ovine prion protein identifies similarities between BSE and an experimental isolate of natural scrapie, CH1641 - Journal of General Virology 1999 Jan; 80(1): 1-4
AFNA - Hope,J.; Shearman,M.S.; Baxter,H.C.; Chong,A.; Kelly,S.M.; Price,N.C. - Cytotoxicity of prion protein peptide (PrP106-126) differs in mechanism from the cytotoxic activity of the Alzheimer's disease amyloid peptide, A beta 25-35 - Neurodegeneration. A Journal for neurodegenerative Disorders, Neuroprotection, and Neuroregeneration 1996 Mar; 5(1): 1-11
AFNB - Hope,J. - Mice and beef and brain diseases - Nature 1995 Dec 21-28; 378(6559): 761-2
AQBZ - Hope,J. - A short history of prions - Nature 1995 Dec 21; 378(6559): 761
AFNC - Hope,J. - The nature of the scrapie agent: the evolution of the virino. - Slow Infections of the Central Nervous System (Ed. Bjornsson, J.; Carp, R.I.; Love, A.; Wisniewski, H.M.) 1994 Jun 6; 724: 282-9
AFND - Hope,J.; Chong,A. - Scrapie, Creutzfeldt-Jakob disease and bovine spongiform encephalopathy: the key role of a nerve membrane protein (PrP). - Biochemical Society Transactions 1994 Feb; 22(1): 159-63
AFNE - Hope,J. - The biology and molecular biology of scrapie-like diseases - Archives of Virology. Supplementum 1993; 7: 201-14
AFNF - Hope,J.; Manson,J. - The scrapie fibril protein and its cellular isoform - Current Topics in Microbiology and Immunology 1991; 172: 57-74
AQCA - Hope,J. - The molecular structure of the infectious particle of scrapie and bovine spongiform encephalopathy : Is a prion a virino in disguise? - Sub-Acute Spongiform Encephalopathies, edited by Ray Bradley, Marc Savey and Brian Marchant - Proceedings of a Seminar in the CEC Agricultural Research Programme, held in Brussels, 12-14 November 1990, 1991; 55: 83-9
AFNG - Hope,J.; Ritchie,L.; Farquhar,C.F.; Somerville,R.; Hunter,N. - Bovine spongiform encephalopathy: a scrapie-like disease of British cattle. - Progress in Clinical and Biological Research 1989; 317: 659-67
AFNH - Hope,J.; Reekie,L.J.; Hunter,N.; Multhaup,G.; Beyreuther,K.; White,H.; Scott,A.C.; Stack,M.J.; Dawson,M.; Wells,G.A.H. - Fibrils from brains of cows with new cattle disease contain scrapie-associated protein - Nature 1988 Nov 24; 336(6197): 390-2
AFNI - Hope,J.; Multhaup,G.; Reekie,L.J.; Kimberlin,R.H.; Beyreuther,K. - Molecular pathology of scrapie-associated fibril protein (PrP) in mouse brain affected by the ME7 strain of scrapie - European Journal of Biochemistry 1988 Mar 1; 172(2): 271-7
AFNJ - Hope,J.; Hunter,N. - Scrapie-associated fibrils, PrP protein and the Sinc gene - Ciba Foundation Symposium 1988; 135: 146-63
AUWN - Hope,J.; Kimberlin,R.H. - The molecular biology of scrapie : the last two years - Trends in Neurosciences 1987; 10: 149-51
AFNK - Hope,J.; Morton,L.J.; Farquhar,C.F.; Multhaup,G.; Beyreuther,K.; Kimberlin,R.H. - The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP) - EMBO Journal 1986 Oct; 5(10): 2591-7
AFSP - Hunter,N.; Foster,J.D.; Goldmann,W.; Stear,M.J.; Hope,J.; Bostock,C.J. - Natural scrapie in a closed flock of Cheviot sheep occurs only in specific PrP genotypes - Archives of Virology 1996; 141(5): 809-24
AFSQ - Hunter,N.; Goldmann,W.; Smith,G.; Hope,J. - Frequencies of PrP gene variants in healthy cattle and cattle with BSE in Scotland - The Veterinary Record 1994 Oct 22; 135(17): 400-3
AFSR - Hunter,N.; Manson,J.C.; Charleson,F.C.; Hope,J. - Comparison of expression patterns of PrP mRNA in the developing sheep and mouse - Annals of the New York Academy of Sciences 1994 Jun 6; 724: 353-4
AFSS - Hunter,N.; Goldmann,W.; Smith,G.; Hope,J. - The association of a codon 136 PrP gene variant with the occurrence of natural scrapie - Archives of Virology 1994; 137(1-2): 171-7
AUVL - Hunter,N.; Goldmann,W.; Benson,G.; Foster,J.D.; Hope,J. - PrP genotype studies - Transmissible Spongiform Encephalopathies. A Consultation on BSE with the Scientific Veterinary Committee of the Commission of the European Communities held in Brussels, September 14-15, 1993. Edited by R. Bradley and B. Marchant. European Commission, Agriculture, Document VI/4131/94-EN 1994, pp. 125-139
AFST - Hunter,N.; Goldmann,W.; Benson,G.; Foster,J.D.; Hope,J. - Swaledale sheep affected by natural scrapie differ significantly in PrP genotype frequencies from healthy sheep and those selected for reduced incidence of scrapie - Journal of General Virology 1993 Jun; 74(6): 1025-31
AFSU - Hunter,N.; Dann,J.C.; Bennett,A.D.; Somerville,R.A.; McConnell,I.; Hope,J. - Are Sinc and the PrP gene congruent? Evidence from PrP gene analysis in Sinc congenic mice - Journal of General Virology 1992 Oct; 73(10): 2751-5
AFSV - Hunter,N.; Foster,J.D.; Hope,J. - Natural scrapie in British sheep: breeds, ages and PrP gene polymorphisms. - The Veterinary Record 1992 May 2; 130(18): 389-92
AFSX - Hunter,N.; Foster,J.D.; Benson,G.; Hope,J. - Restriction fragment length polymorphisms of the scrapie-associated fibril protein (PrP) gene and their association with susceptibility to natural scrapie in British sheep - Journal of General Virology 1991 Jun; 72(6): 1287-92
AFSZ - Hunter,N.; Foster,J.D.; Dickinson,A.G.; Hope,J. - Linkage of the gene for the scrapie-associated fibril protein (PrP) to the Sip gene in Cheviot sheep - The Veterinary Record 1989 Apr 8; 124(14): 364-6
AFTA - Hunter,N.; Hope,J.; McConnell,I.; Dickinson,A.G. - Linkage of the scrapie-associated fibril protein (PrP) gene and Sinc using congenic mice and restriction fragment length polymorphism analysis - Journal of General Virology 1987 Oct; 68(10): 2711-6
AFZI - Jeffrey,M.J.; Goodsir,C.M.; Fowler,N.; Hope,J.; Bruce,M.E.; McBride,P.A. - Ultrastructural immuno-localization of synthetic prion protein peptide antibodies in 87V murine scrapie - Neurodegeneration. A Journal for neurodegenerative Disorders, Neuroprotection, and Neuroregeneration 1996 Mar; 5(1): 101-9
ASGP - Johnston,A.R.; Black,C.J.; Fraser,J.R.; Manson,J.C.; Hope,J.; Clarke,A.R.; MacLeod,N. - Membrane-properties and synaptic plasticity in mouse ca1 hippocampal-neurons infected with me-7 scrapie or lacking the prion protein, studied in-vitro - Journal of Physiology 1996 Sep; 495: 15
AGHY - Kenward,N.; Hope,J.; Landon,M.; Mayer,R.J. - Expression of polyubiquitin and heat-shock protein 70 genes increases in the later stages of disease progression in scrapie-infected mouse brain - Journal of Neurochemistry 1994 May; 62(5): 1870-7
AGHZ - Kenward,N.; Laszlo,L.; Landon,M.; Fergusson,J.; Lowe,J.; McDermott,H.; Hope,J.; Brown,J.; Mayer,R.J. - A role for lysosomes in scrapie pathogenesis - Biochemical Society Transactions 1992 Aug; 20(3): 265S
AUWO - Kimberlin,R.H.; Hope,J. - Genes and genomes in scrapie - Trends in Genetics 1987; 3: 117-8
ANRG - Kirby,L.; Birkett,C.R.; Rudyk,H.; Gilbert,I.H.; Hope,J. - In vitro cell-free conversion of bacterial recombinant PrP to PrPres as a model for conversion - Journal of General Virology 2003 Apr; 84(4): 1013-20
AHBL - Laszlo,L.; Lowe,J.; Self,T.; Kenward,N.; Landon,M.; McBride,P.A.; Farquhar,C.F.; McConnell,I.; Brown,J.M.; Hope,J.; Mayer,R.J. - Lysosomes as key organelles in the pathogenesis of prion encephalopathies - Journal of Pathology 1992 Apr; 166(4): 333-41
AHNZ - Lowe,J.; Fergusson,J.; Kenward,N.; Laszlo,L.; Landon,M.; Farquhar,C.F.; Brown,J.; Hope,J.; Mayer,R.J. - Immunoreactivity to ubiquitin-protein conjugates is present early in the disease process in the brains of scrapie-infected mice - Journal of Pathology 1992 Oct; 168(2): 169-77
AHOA - Lowe,J.; McDermott,H.; Kenward,N.; Landon,M.; Mayer,R.J.; Bruce,M.E.; McBride,P.A.; Somerville,R.A.; Hope,J. - Ubiquitin conjugate immunoreactivity in the brains of scrapie infected mice - Journal of Pathology 1990 Sep; 162(1): 61-6
AHQW - MacGregor,I.R.; Hope,J.; Barnard,G.; Kirby,L.; Drummond,O.; Pepper,D.; Hornsey,V.; Barclay,G.R.; Bessos,H.; Turner,M.L.; Prowse,C.V. - Application of a time-resolved fluoroimmunoassay for the analysis of normal prion protein in human blood and its components - Vox Sanguinis 1999; 77(2): 88-96
AHRD - Maciulis,A.; Hunter,N.; Wang,S.; Goldmann,W.; Hope,J.; Foote,W.C. - Polymorphisms of a scrapie-associated fibril protein (PrP) gene and their association with susceptibility to experimentally induced scrapie in Cheviot sheep in the United States - American Journal of Veterinary Research 1992 Oct; 53(10): 1957-60
AHTV - Manson,J.C.; Barron,R.M.; Jamieson,E.; Baybutt,H.N.; Tuzi,N.L.; McConnell,I.; Melton,D.; Hope,J.; Bostock,C.J. - A single amino acid alteration in murine PrP dramatically alters TSE incubation time - Archives of Virology. Supplementum 2000(16): 95-102
AHTX - Manson,J.C.; Jamieson,E.; Baybutt,H.N.; Tuzi,N.L.; Barron,R.M.; McConnell,I.; Somerville,R.; Ironside,J.; Will,R.; Sy,M.S.; Melton,D.W.; Hope,J.; Bostock,C.J. - A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy - EMBO Journal 1999 Dec 1; 18(23): 6855-64
AHTY - Manson,J.C.; Clarke,A.R.; McBride,P.A.; McConnell,I.; Hope,J. - PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology - Neurodegeneration. A Journal for neurodegenerative Disorders, Neuroprotection, and Neuroregeneration 1994 Dec; 3(4): 331-40
AHTZ - Manson,J.C.; Clarke,A.R.; Hooper,M.L.; Aitchison,L.; McConnell,I.; Hope,J. - 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal - Molecular Neurobiology 1994 Apr-Jun; 8(2-3): 121-7
AHTU - Manson,J.C.; West,J.D.; Thomson,V.; McBride,P.A.; Kaufman,M.H.; Hope,J. - The prion protein gene: a role in mouse embryogenesis? - Development 1992 May; 115(1): 117-22
AAPD - Manson,J.C.; Hope,J. - Anti-prions and other agents - Nature 1991 Jul 25; 352(6333): 291
AICX - Mayer,R.J.; Laszlo,L.; Landon,M.; Hope,J.; Lowe,J. - Ubiquitin, lysosomes, and neurodegenerative diseases - Annals of the New York Academy of Sciences 1992 Dec 31; 674: 149-60
AIMQ - Mohri,S.; Farquhar,C.F.; Somerville,R.A.; Jeffrey,M.J.; Foster,J.; Hope,J. - Immunodetection of a disease specific PrP fraction in scrapie-affected sheep and BSE-affected cattle - The Veterinary Record 1992 Dec 5; 131(23): 537-9
AINS - Moore,R.C.; Hope,J.; McBride,P.A.; McConnell,I.; Selfridge,J.; Melton,D.W.; Manson,J.C. - Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent - Nature Genetics 1998 Feb; 18(2): 118-25
AINU - Moore,R.C.; Redhead,N.J.; Selfridge,J.; Hope,J.; Manson,J.C.; Melton,D.W. - Double replacement gene targeting for the production of a series of mouse strains with different prion protein gene alterations - Bio/Technology 1995 Sep; 13(9): 999-1004
AJIC - Pearson,G.R.; Wyatt,J.M.; Gruffydd-Jones,T.J.; Hope,J.; Chong,A.; Higgins,R.J.; Scott,A.C.; Wells,G.A.H. - Feline spongiform encephalopathy: fibril and PrP studies. - The Veterinary Record 1992 Oct 3; 131(14): 307-10
ATAK - Pearson,G.R.; Gruffydd-Jones,T.J.; Wyatt,J.M.; Hope,J.; Chong,A.; Scott,A.C.; Dawson,M.; Wells,G.A.H. - Feline spongiform encephalopathy - The Veterinary Record 1991 Jun 1; 128(22): 532
AJQG - Prowse,C.V.; Hornsey,V.S.; Drummond,O.; MacGregor,I.R.; Pepper,D.S.; Barclay,G.R.; Bethel,H.; Walker,B.; Barnard,G.; Kirby,L.; Hope,J. - Preliminary assessment of whole-blood, red-cell and platelet- leucodepleting filters for possible induction of prion release by leucocyte fragmentation during room temperature processing - British Journal of Haematology 1999 Jul; 106(1): 240-7
AJWV - Raymond,G.J.; Hope,J.; Kocisko,D.A.; Priola,S.A.; Raymond,L.D.; Bossers,A.; Ironside,J.; Will,R.G.; Chen,S.G.; Petersen,R.B.; Gambetti,P.; Rubenstein,R.; Smits,M.A.; Lansbury,P.T.Jr.; Caughey,B.W. - Molecular assessment of the potential transmissibilities of BSE and scrapie to humans - Nature 1997 Jul 17; 388(6639): 285-8
APLC - Rhie,A.; Kirby,L.; Sayer,N.; Wellesley,R.; Disterer,P.; Sylvester,I.; Gill,A.; Hope,J.; James,W.; Tahiri-Alaoui,A. - Characterization of 2'-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion - The Journal of Biological Chemistry 2003 Oct 10; 278(41): 39697-705
APLG - Rudyk,H.; Knaggs,M.H.; Vasiljevic,S.; Hope,J.; Birkett,C.R.; Gilbert,I.H. - Synthesis and evaluation of analogues of Congo red as potential compounds against transmissible spongiform encephalopathies - European Journal of Medicinal Chemistry 2003 Jun; 38(6): 567-79
AKGB - Rudyk,H.; Vasiljevic,S.; Hennion,R.M.; Birkett,C.R.; Hope,J.; Gilbert,I.H. - Screening Congo Red and its analogues for their ability to prevent the formation of PrPres in scrapie-infected cells - Journal of General Virology 2000 Apr; 81(4): 1155-64
AVHR - Saunders,G.C.; Cawthraw,S.; Mountjoy,S.J.; Hope,J.; Windl,O. - PrP genotypes of atypical scrapie cases in Great Britain - Journal of General Virology 2006 Nov; 87(11): 3141-9
AWNG - Saunders,G.C.; Cawthraw,S.; Mountjoy,S.J.; Hope,J.; Windl,O. - PrP gene polymorphisms in atypical scrapie cases in Great Britain - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions GEN-26
ATMQ - Saunders,G.C.; Cawthraw,S.; Mountjoy,S.J.; Hope,J.; Windl,O. - PrP genotype of atypical scrapie cases in Great Britain - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Genetics, strains and emerging problems GEN-16
AKPZ - Scott,J.R.; Reekie,L.J.D.; Hope,J. - Evidence for intrinsic control of scrapie pathogenesis in the murine visual system - Neuroscience Letters 1991 Nov 25; 133(1): 141-4
ALAJ - Somerville,R.A.; Chong,A.; Mulqueen,O.U.; Birkett,C.R.; Wood,S.C.E.R.; Hope,J. - Biochemical typing of scrapie strains - Nature 1997 Apr 10; 386(6625): 564
AUPM - Stack,M.J.; Jeffrey,M.J.; Gubbins,S.; Grimmer,S.; Gonzalez,L.; Martin,S.; Chaplin,M.J.; Webb,P.; Simmons,M.M.; Spencer,Y.; Bellerby,P.J.; Hope,J.; Wilesmith,J.W.; Matthews,D. - Monitoring for bovine spongiform encephalopathy in sheep in Great Britain, 1998-2004 - Journal of General Virology 2006 Jul; 87(7): 2099-107
ALEL - Stimson,E.; Hope,J.; Chong,A.; Burlingame,A.L. - Site-specific characterization of the N-linked glycans of murine prion protein by high-performance liquid chromatography/electrospray mass spectrometry and exoglycosidase digestions - Biochemistry 1999 Apr 13; 38(15): 4885-95
AWOT - Terry,L.A.; Thorne,L.; Jenkins,R.; Everest,S.; Jackman,R.; Hope,J. - Biochemical and immunological characterisation of the UK atypical scrapie strain - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PR-33