AXPS - Keane,D.; Barr,D.; Bochsler,P.; Hall,M.; Gidlewski,T.; O'Rourke,K.; Spraker,T. - Chronic Wasting Disease in a Captive White-Tailed Deer Farm - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Epidemiology, Risk Assessment and Transmission P04.01
AXTV - O'Rourke,K.; Spraker,T.R.; Greenlee,J.J.; Gidlewiski,T.E.; Hamir,A.N. - Prolonged Incubation Time and Differential Processing of PrP-CWD in Experimentally Infected Rocky Mountain Elk Lacking the 132M Prnp Allele - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Protein Misfolding P01.44
AXXA - Spraker,T.; Greenlee,J.; Gidlewski,T.; O'Rourke,K. - Abnormal Prion Protein in the Retina of Rocky Mountain Elk (Cervus Elaphus Nelsoni) - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.70
AXYS - White,S.; O'Rourke,K.; Mousel,M.; Spraker,T. - Combining Information on Cation Levels Improves Association with Chronic Wasting Disease in Elk - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Epidemiology, Risk Assessment and Transmission P04.10
AXZR - Zheng,M.; Qing,L.; Huang,S.; Chen,F.; Wang,M.; Wang,L.; Miller,M.; Hamir,A.N.; Richt,J.A.; O'Rourke,K.; Belay,E.D.; Schonberger,L.B.; Gambetti,P.; Kong,Q. - Assessment of Direct and Indirect Transmission of CWD from Three Cervid Species to Humans - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Oral Abstracts FC5.8
AUFU - Alexander,B.M.; Stobart,R.H.; Russell,W.C.; O'Rourke,K.I.; Lewis,G.S.; Logan,J.R.; Duncan,J.V.; Moss,G.E. - The incidence of genotypes at codon 171 of the prion protein gene (PRNP) in five breeds of sheep and production traits of ewes associated with those genotypes - Journal of Animal Science 2005 Feb; 83(2): 455-9
AUBW - Alverson,J.; O'Rourke,K.I.; Baszler,T.V. - PrPsc accumulation in fetal cotyledons of scrapie-resistant lambs is influenced by fetus location in the uterus - Journal of General Virology 2006 Apr; 87(4): 1035-41
AWBI - Balachandran,A.V.; O'Rourke,K.I.; Spraker,T.R.; Stack,M.J. - Diagnosis of CWD: current situation in Canada and ongoing research projects - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre, Workshop of the Neuroprion Cervid Group - Chronic Wasting Disease (CWD): Current knowledge and European perspective 2006, 3.10.2006
AUGS - Baszler,T.V.; Kiupel,M.; Williams,E.S.; Thomsen,B.V.; Gidlewski,T.; Montgomery,D.L.; O'Rourke,K.I.; Hall,S.M. - Comparison of two automated immunohistochemical procedures for the diagnosis of scrapie in domestic sheep and chronic wasting disease in North American white-tailed deer (Odocoileus virginianus) and mule deer (Odocoileus hemionus) - Journal of Veterinary Diagnostic Investigation 2006 Mar; 18(2): 147-55
AQSB - Bender,S.; Alverson,J.; Herrmann,L.M.; O'Rourke,K.I. - Histamine as an aid to biopsy of third eyelid lymphoid tissue in sheep - The Veterinary Record 2004 May 22; 154(21): 662-3
APUC - Brayton,K.A.; O'Rourke,K.I.; Lyda,A.K.; Miller,M.W.; Knowles,D.P. - A processed pseudogene contributes to apparent mule deer prion gene heterogeneity - Gene 2004 Feb 4; 326: 167-73
ARGD - Caplazi,P.A.; O'Rourke,K.I.; Wolf,C.; Shaw,D.; Baszler,T.V. - Biology of PrPsc accumulation in two natural scrapie-infected sheep flocks - Journal of Veterinary Diagnostic Investigation 2004 Nov; 16(6): 489-96
AQSH - Caplazi,P.A.; O'Rourke,K.I.; Baszler,T.V. - Resistance to scrapie in PrP ARR/ARQ heterozygous sheep is not caused by preferential allelic use - Journal of Clinical Pathology 2004 Jun; 57(6): 647-50
AWEP - Evoniuk,J.M.; Johnson,M.L.; Larson,D.M.; Taylor,J.B.; Stoltenow,C.L.; Reynolds,L.P.; Vonnahme,K.A.; Caton,J.S.; O'Rourke,K.I.; Redmer,D.A. - Localization and quantification of prion protein (PrPc) expression in sheep placenta - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions CE-12
ATHK - Evoniuk,J.M.; Johnson,M.L.; Caton,J.S.; Taylor,J.B.; Stoltenow,C.L.; O'Rourke,K.I.; Redmer,D.A. - Quantification of prion protein (PrPc) gene expression in the fetal and maternal sheep placenta - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Cell Biology of PrPc and PrPsc CELL-16
ASZR - Evoniuk,J.M.; Stoltenow,C.L.; O'Rourke,K.I.; Moore,B.L.; Redmer,D.A. - Assessment of the genetic risk and impact of lateral transmission in a valine-associated scrapie outbreak in sheep - American Journal of Veterinary Research 2005 Aug; 66(8): 1302-7
AVUR - Hamir,A.N.; Gidlewski,T.; Spraker,T.R.; Miller,J.M.; Creekmore,L.; Crocheck,M.; Cline,T.F.; O'Rourke,K.I. - Preliminary observations of genetic susceptibility of elk (Cervus elaphus nelsoni) to chronic wasting disease by experimental oral inoculation - Journal of Veterinary Diagnostic Investigation 2006 Jan; 18(1): 110-4
ASPF - Hamir,A.N.; Kunkle,R.A.; Cutlip,R.C.; Miller,J.M.; O'Rourke,K.I.; Williams,E.S.; Miller,M.W.; Stack,M.J.; Chaplin,M.J.; Richt,J.A. - Experimental transmission of chronic wasting disease agent from mule deer to cattle by the intracerebral route - Journal of Veterinary Diagnostic Investigation 2005 May; 17(3): 276-81
AQKH - Hamir,A.N.; Miller,J.M.; O'Rourke,K.I.; Bartz,J.C.; Stack,M.J.; Chaplin,M.J. - Transmission of transmissible mink encephalopathy to raccoons (Procyon lotor) by intracerebral inoculation - Journal of Veterinary Diagnostic Investigation 2004 Jan; 16(1): 57-63
AFBO - Hamir,A.N.; Cutlip,R.C.; Miller,J.M.; Williams,E.S.; Stack,M.J.; Miller,M.W.; O'Rourke,K.I.; Chaplin,M.J. - Preliminary findings on the experimental transmission of chronic wasting disease agent of mule deer to cattle - Journal of Veterinary Diagnostic Investigation 2001 Jan; 13(1): 91-6
AUHS - Herrmann,L.M.; Baszler,T.V.; O'Rourke,K.I.; Suarez,C.E.; Bakko,M.; Alverson,J.; Knowles,D.P. - Fewer PrPc myeloid-based cells in sheep with the prion-resistant genotype - Neuroreport 2006 Feb 6; 17(2): 125-9
ANQT - Herrmann,L.M.; Cheevers,W.P.; Davis,W.C.; Knowles,D.P.; O'Rourke,K.I. - CD21-Positive Follicular Dendritic Cells: A Possible Source of PrPsc in Lymph Node Macrophages of Scrapie-Infected Sheep. - American Journal of Pathology 2003 Apr; 162(4): 1075-81
AFIR - Herrmann,L.M.; Davis,W.C.; Knowles,D.P.; Wardrop,K.J.; Sy,M.S.; Gambetti,P.; O'Rourke,K.I. - Cellular prion protein is expressed on peripheral blood mononuclear cells but not platelets of normal and scrapie-infected sheep - Haematologica 2001 Feb; 86(2): 146-53
ATCX - Huang,H.; Rendulich,J.; Stevenson,D.; O'Rourke,K.I.; Balachandran,A.V. - Evaluation of Western blotting methods using samples with or without sodium phosphotungstic acid precipitation for diagnosis of scrapie and chronic wasting disease - Canadian Journal of Veterinary Research 2005 Jul; 69(3): 193-9
AYHD - Johnson,M.L.; Evoniuk,J.M.; Stoltenow,C.L.; O'Rourke,K.I.; Redmer,D.A. - Development of an assay to determine single nucleotide polymorphisms in the prion gene for the genetic diagnosis of relative susceptibility to classical scrapie in sheep - Journal of Veterinary Diagnostic Investigation 2007 Jan; 19(1): 73-7
AWHP - Johnson,M.L.; Luther,J.S.; Wallace,J.M.; Evoniuk,J.M.; Reynolds,L.P.; Stoltenow,C.L.; O'Rourke,K.I.; Redmer,D.A. - Effects of nutrition and genotype on cellular prion protein (PrPc) mRNA expression in ovine placental tissues - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions CE-20
ATHN - Johnson,M.L.; Evoniuk,J.M.; Reynolds,L.P.; Stoltenow,C.L.; O'Rourke,K.I.; Redmer,D.A. - Evaluation of cellular prion protein (PrPc) mRNA expression in ovine tissues and after estradiol-17ß treatment of ovariectomized (OVX) ewes - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Cell Biology of PrPc and PrPsc CELL-19
AGIT - Kim,H.; O'Rourke,K.I.; Walter,M.; Purchase,H.G.; Enck,J.; Shin,T.K. - Immunohistochemical detection of scrapie prion proteins in clinically normal sheep in Pennsylvania - Journal of Veterinary Diagnostic Investigation 2001 Jan; 13(1): 89-91
ATDF - Kong,Q.; Huang,S.; Zou,W.Q.; Vanegas,D.; Wang,M.; Wu,D.; Yuan,J.; Zheng,M.; Bai,H.; Deng,H.; Chen,K.; Jenny,A.L.; O'Rourke,K.I.; Belay,E.D.; Schonberger,L.B.; Petersen,R.B.; Sy,M.S.; Chen,S.G.; Gambetti,P. - Chronic wasting disease of elk: transmissibility to humans examined by transgenic mouse models. - Journal of Neuroscience 2005 Aug 31; 25(35): 7944-9
APIV - Koo,H.C.; Park,Y.H.; Lee,B.C.; Chae,C.; O'Rourke,K.I.; Baszler,T.V. - Immunohistochemical detection of Prion protein (PrP-Sc) and epidemiological study of BSE in Korea - Journal of Veterinary Science (Suwon-si, Korea) 2001 Apr; 2(1): 25-31
AHGC - Li,R.; Liu,T.; Wong,B.S.; Pan,T.; Morillas,M.; Swietnicki,W.; O'Rourke,K.I.; Gambetti,P.; Surewicz,W.K.; Sy,M.S. - Identification of an epitope in the C terminus of normal prion protein whose expression is modulated by binding events in the N terminus - Journal of Molecular Biology 2000 Aug 18; 301(3): 567-73
AWLH - O'Rourke,K.I.; Herrmann,L.M. - The role of prenatal and postnatal ovine chimerism in scrapie control programs - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions GEN-20
AWLG - O'Rourke,K.I.; Spraker,T.R.; Ernest,H. - Species specific influence of genotype on CWD susceptibility - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre, Workshop of the Neuroprion Cervid Group - Chronic Wasting Disease (CWD): Current knowledge and European perspective 2006, 3.10.2006
ASXM - O'Rourke,K.I. - USDA takes steps to battle CWD - Journal of the American Veterinary Medical Association 2005 Jun 15; 226(12): 1962-3
ASQS - O'Rourke,K.I. - CWD found in New York - Journal of the American Veterinary Medical Association 2005 May 15; 226(10): 1633
ARSI - O'Rourke,K.I. - Prion study raises questions - Journal of the American Veterinary Medical Association 2005 Mar 1; 226(5): 677-8
ARSJ - O'Rourke,K.I. - The Canada debate. USDA sends team to Canada to investigate BSE situation. - Journal of the American Veterinary Medical Association 2005 Feb 15; 226(4): 504-5
ARIW - O'Rourke,K.I. - O.I.E. takes action at annual meeting. Agency acts on measures involving BSE, zoonoses, animal welfare, and the disease notification system. - Journal of the American Veterinary Medical Association 2004 Aug 15; 225(4): 486-7
AQNH - O'Rourke,K.I.; Spraker,T.R.; Hamburg,L.K.; Besser,T.E.; Brayton,K.A.; Knowles,D.P. - Polymorphisms in the prion precursor functional gene but not the pseudogene are associated with susceptibility to chronic wasting disease in white-tailed deer - Journal of General Virology 2004 May; 85(5): 1339-46
AQRD - O'Rourke,K.I. - New form of BSE sparks discussion - Journal of the American Veterinary Medical Association 2004 Apr 15; 224(8): 1233-4
AOMC - O'Rourke,K.I.; Zhuang,D.; Lyda,A.; Gomez,G.; Williams,E.S.; Tuo,W.; Miller,M.W. - Abundant PrP(CWD) in tonsil from mule deer with preclinical chronic wasting disease - Journal of Veterinary Diagnostic Investigation 2003 Jul; 15(4): 320-3
AIYY - O'Rourke,K.I.; Duncan,J.V.; Logan,J.R.; Anderson,A.K.; Norden,D.K.; Williams,E.S.; Combs,B.A.; Stobart,R.H.; Moss,G.E.; Sutton,D.L. - Active surveillance for scrapie by third eyelid biopsy and genetic susceptibility testing of flocks of sheep in Wyoming - Clinical and Diagnostic Laboratory Immunology 2002 Sep; 9(5): 966-71
AIYZ - O'Rourke,K.I. - Ovine scrapie. New tools for control of an old disease. - Veterinary Clinics of North America. Food Animal Practice 2001 Jul; 17(2): 283-300, vi
AIZA - O'Rourke,K.I.; Baszler,T.V.; Besser,T.E.; Miller,J.M.; Cutlip,R.C.; Wells,G.A.H.; Ryder,S.J.; Parish,S.M.; Hamir,A.N.; Cockett,N.E.; Jenny,A.; Knowles,D.P. - Preclinical diagnosis of scrapie by immunohistochemistry of third eyelid lymphoid tissue - Journal of Clinical Microbiology 2000 Sep; 38(9): 3254-9
AIZB - O'Rourke,K.I.; Besser,T.E.; Miller,M.W.; Cline,T.F.; Spraker,T.R.; Jenny,A.L.; Wild,M.A.; Zebarth,G.L.; Williams,E.S. - PrP genotypes of captive and free-ranging Rocky Mountain elk (Cervus elaphus nelsoni) with chronic wasting disease - Journal of General Virology 1999 Oct; 80(10): 2765-9
AIZC - O'Rourke,K.I.; Baszler,T.V.; Miller,J.M.; Spraker,T.R.; Sadler-Riggleman,I.; Knowles,D.P. - Monoclonal antibody F89/160.1.5 defines a conserved epitope on the ruminant prion protein. - Journal of Clinical Microbiology 1998 Jun; 36(6): 1750-5
AIZD - O'Rourke,K.I.; Baszler,T.V.; Parish,S.M.; Knowles,D.P. - Preclinical detection of PrPsc in nictitating membrane lymphoid tissue of sheep - The Veterinary Record 1998 May 2; 142(18): 489-91
AIZE - O'Rourke,K.I.; Holyoak,G.R.; Clark,W.W.; Mickelson,J.R.; Wang,S.; Melco,R.P.; Besser,T.E.; Foote,W.C. - PrP genotypes and experimental scrapie in orally inoculated Suffolk sheep in the United States - Journal of General Virology 1997 Apr; 78(4): 975-8
ASDS - O'Rourke,K.I.; Melco,R.P.; Mickelson,J.R. - Allelic frequencies of an ovine scrapie susceptibility gene - Animal Biotechnology 1996; 7(N2): 155-62
AIZF - O'Rourke,K.I.; Huff,T.P.; Leathers,C.W.; Robinson,M.M.; Gorham,J.R. - SCID mouse spleen does not support scrapie agent replication - Journal of General Virology 1994 Jun; 75(6): 1511-4
APVG - Paramithiotis,E.; Pinard,M.; Lawton,T.; LaBoissiere,S.; Leathers,V.L.; Zou,W.Q.; Estey,L.A.; Lamontagne,J.; Lehto,M.T.; Kondejewski,L.H.; Francoeur,G.P.; Papadopoulos,M.; Haghighat,A.; Spatz,S.J.; Head,M.; Will,R.; Ironside,J.; O'Rourke,K.I.; Tonelli,Q.; Ledebur,H.C.Jr.; Chakrabartty,A.; Cashman,N.R. - Reply to "Properties of a disease-specific prion probe" - Nature Medicine 2004 Jan; 10(1): 11-2
ANYX - Paramithiotis,E.; Pinard,M.; Lawton,T.; LaBoissiere,S.; Leathers,V.L.; Zou,W.Q.; Estey,L.A.; Lamontagne,J.; Lehto,M.T.; Kondejewski,L.H.; Francoeur,G.P.; Papadopoulos,M.; Haghighat,A.; Spatz,S.J.; Head,M.; Will,R.; Ironside,J.; O'Rourke,K.I.; Tonelli,Q.; Ledebur,H.C.Jr.; Chakrabartty,A.; Cashman,N.R. - A prion protein epitope selective for the pathologically misfolded conformation - Nature Medicine 2003 Jul; 9(7): 893-9
AJWU - Raymond,G.J.; Bossers,A.; Raymond,L.D.; O'Rourke,K.I.; McHolland,L.E.; Bryant,P.K.3rd; Miller,M.W.; Williams,E.S.; Smits,M.; Caughey,B.W. - Evidence of a molecular barrier limiting susceptibility of humans, cattle and sheep to chronic wasting disease - EMBO Journal 2000 Sep 1; 19(17): 4425-30
AKWB - Sigurdson,C.J.; Williams,E.S.; Miller,M.W.; Spraker,T.R.; O'Rourke,K.I.; Hoover,E.A. - Oral transmission and early lymphoid tropism of chronic wasting disease PrPres in mule deer fawns (Odocoileus hemionus) - Journal of General Virology 1999 Oct; 80(10): 2757-64
AQWV - Spraker,T.R.; Balachandran,A.V.; Zhuang,D.; O'Rourke,K.I. - Variable patterns of distribution of PrP(CWD) in the obex and cranial lymphoid tissues of Rocky Mountain elk (Cervus elaphus nelsoni) with subclinical chronic wasting disease - The Veterinary Record 2004 Sep 4; 155(10): 295-302
ALBZ - Spraker,T.R.; Zink,R.R.; Cummings,B.A.; Sigurdson,C.J.; Miller,M.W.; O'Rourke,K.I. - Distribution of protease-resistant prion protein and spongiform encephalopathy in free-ranging mule deer (Odocoileus hemionus) with chronic wasting disease - Veterinary Pathology 2002 Sep; 39(5): 546-56
ANVJ - Spraker,T.R.; O'Rourke,K.I.; Balachandran,A.V.; Zink,R.R.; Cummings,B.A.; Miller,M.W.; Powers,B.E. - Validation of monoclonal antibody F99/97.6.1 for immunohistochemical staining of brain and tonsil in mule deer (Odocoileus hemionus) with chronic wasting disease. - Journal of Veterinary Diagnostic Investigation 2002 Jan; 14(1): 3-7
ALCA - Spraker,T.R.; Zink,R.R.; Cummings,B.A.; Wild,M.A.; Miller,M.W.; O'Rourke,K.I. - Comparison of histological lesions and immunohistochemical staining of proteinase-resistant prion protein in a naturally occurring spongiform encephalopathy of free-ranging mule deer (Odocoileus hemionus) with those of chronic wasting disease of captive mule deer - Veterinary Pathology 2002 Jan; 39(1): 110-9
ALCB - Spraker,T.R.; Miller,M.W.; Williams,E.S.; Getzy,D.M.; Adrian,W.J.; Schoonveld,G.G.; Spowart,R.A.; O'Rourke,K.I.; Miller,J.M.; Merz,P.A. - Spongiform encephalopathy in free-ranging mule deer (Odocoileus hemionus), white-tailed deer (Odocoileus virginianus) and Rocky Mountain elk (Cervus elaphus nelsoni) in northcentral Colorado - Journal of Wildlife Diseases 1997 Jan; 33(1): 1-6
ALUR - Tuo,W.; O'Rourke,K.I.; Zhuang,D.; Cheevers,W.P.; Spraker,T.R.; Knowles,D.P. - Pregnancy status and fetal prion genetics determine PrPsc accumulation in placentomes of scrapie-infected sheep - Proceedings of the National Academy of Sciences of the United States of America 2002 Apr 30; 99(9): 6310-5
ALUS - Tuo,W.; Zhuang,D.; Knowles,D.P.; Cheevers,W.P.; Sy,M.S.; O'Rourke,K.I. - Prp-c and Prp-Sc at the fetal-maternal interface - The Journal of Biological Chemistry 2001 May 25; 276(21): 18229-34
ALVE - Tyler,J.W.; Weaver,D.M.; Turk,J.R.; O'Rourke,K.I.; Harrington,M.G.; Taylor,W.; Jenny,A. - Naturally occurring scrapie in Southdown sheep - Journal of Veterinary Internal Medicine 1999 May-Jun; 13(3): 213-6
ANTE - Valdez,R.A.; Rock,M.J.; Anderson,A.K.; O'Rourke,K.I. - Immunohistochemical detection and distribution of prion protein in a goat with natural scrapie - Journal of Veterinary Diagnostic Investigation 2003 Mar; 15(2): 157-62
ALYH - van Everbroeck,B.R.J.; O'Rourke,K.I.; Cras,P. - Immunoreactivity of the monoclonal antibody F89/160.1.5 for the human prion protein. - European Journal of Histochemistry 1999; 43(4): 335-8
AMMQ - Wild,M.A.; Spraker,T.R.; Sigurdson,C.J.; O'Rourke,K.I.; Miller,M.W. - Preclinical diagnosis of chronic wasting disease in captive mule deer (Odocoileus hemionus) and white-tailed deer (Odocoileus virginianus) using tonsillar biopsy - Journal of General Virology 2002 Oct; 83(10): 2629-34
AUEN - Xie,Z.; O'Rourke,K.I.; Dong,Z.; Jenny,A.L.; Langenberg,J.A.; Belay,E.D.; Schonberger,L.B.; Petersen,R.B.; Zou,W.Q.; Kong,Q.; Gambetti,P.; Chen,S.G. - Chronic wasting disease of elk and deer and Creutzfeldt-Jakob disease: comparative analysis of the scrapie prion protein. - The Journal of Biological Chemistry 2006 Feb 17; 281(7): 4199-206