AXZY - Aguzzi,A. - Prion biology: the quest for the test. - Nature Methods 2007 Aug; 4(8): 614-6
AXDW - Aguzzi,A.; Heikenwalder,M.; Polymenidou,M. - Insights into prion strains and neurotoxicity - Nature Reviews. Molecular Cell Biology 2007 Jul; 8(7): 552-61
AVFE - Aguzzi,A.; Heikenwalder,M. - Pathogenesis of prion diseases: current status and future outlook. - Nature Reviews. Microbiology 2006 Oct; 4(10): 765-75
AWAW - Aguzzi,A. - Recent progress in prion biology - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Oral sessions ORAL-41
AVAI - Aguzzi,A.; Glatzel,M. - Prion infections, blood and transfusions - Nature Clinical Practice. Neurology 2006 Jun; 2(6): 321-9
AUXM - Aguzzi,A. - Prion diseases of humans and farm animals: epidemiology, genetics, and pathogenesis. - Journal of Neurochemistry 2006 Jun; 97(6): 1726-39
ATFE - Aguzzi,A. - The role of the immune system in peripheral prion pathogenesis - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Oral sessions ORAL-09
ASLZ - Aguzzi,A. - Cell biology. Prion toxicity: all sail and no anchor. - Science 2005 Jun 3; 308(5727): 1420-1
ARNL - Aguzzi,A.; Heikenwalder,M. - Prions, cytokines, and chemokines: a meeting in lymphoid organs. - Immunity 2005 Feb; 22(2): 145-54
AQZQ - Aguzzi,A.; Sigurdson,C.J. - Antiprion immunotherapy: to suppress or to stimulate? - Nature Reviews. Immunology 2004 Sep; 4(9): 725-36
AQVM - Aguzzi,A.; Heikenwalder,M.; Miele,G. - Progress and problems in the biology, diagnostics, and therapeutics of prion diseases - Journal of Clinical Investigation 2004 Jul; 114(2): 153-60
AQQV - Aguzzi,A.; Miele,G. - Recent advances in prion biology - Current Opinion in Neurology 2004 Jun; 17(3): 337-42
AQHE - Aguzzi,A. - Understanding the diversity of prions - Nature Cell Biology 2004 Apr; 6(4): 290-2
APWZ - Aguzzi,A.; Glatzel,M. - vCJD tissue distribution and transmission by transfusion - a worst-case scenario coming true? - Lancet 2004 Feb 7; 363(9407): 411-2
APTT - Aguzzi,A.; Polymenidou,M. - Mammalian prion biology: one century of evolving concepts. - Cell 2004 Jan 23; 116(2): 313-27
APQF - Aguzzi,A. - Prions and the immune system: a journey through gut, spleen, and nerves. - Advances in Immunology 2003; 81: 123-71
APEJ - Aguzzi,A.; Haass,C. - Games played by rogue proteins in prion disorders and Alzheimer's disease - Science 2003 Oct 31; 302(5646): 814-8
AOPP - Aguzzi,A. - The immunobiology of prion diseases - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Oral sessions OS-19
APEK - Aguzzi,A.; Heppner,F.L.; Heikenwalder,M.; Prinz,M.; Mertz,K.; Seeger,H.; Glatzel,M. - Immune system and peripheral nerves in propagation of prions to CNS - British Medical Bulletin 2003 Sep; 66(1): 141-59
AOEU - Aguzzi,A.; Hardt,W.D. - Dangerous liaisons between a microbe and the prion protein - Journal of Experimental Medicine 2003 Jul 7; 198(1): 1-4
ANWK - Aguzzi,A.; Heikenwalder,M. - Prion diseases: Cannibals and garbage piles. - Nature 2003 May 8; 423(6936): 127-9
ASYP - Aguzzi,A. - A practical prion protein primer - Advances in Protein Chemistry: Prion Proteins, edited by Byron Caughey - Nature 2002 Mar; 416(4): E61
AACU - Aguzzi,A. - [The prion hypothesis and the human prion diseases] - Die Prion-Hypothese und Prionen-Krankheiten des Menschen - Berliner und Münchener Tierärztliche Wochenschrift 2002 Mar-Apr; 115(3-4): 91-8
AACV - Aguzzi,A.; Glatzel,M.; Montrasio,F.; Prinz,M.; Heppner,F.L. - Interventional strategies against prion diseases - Nature Reviews. Neuroscience 2001 Oct; 2(10): 745-9
AACW - Aguzzi,A. - Peripheral prion pursuit - Journal of Clinical Investigation 2001 Sep; 108(5): 661-2
AACX - Aguzzi,A.; Brandner,S.; Fischer,M.B.; Furukawa,H.; Glatzel,M.; Hawkins,C.; Heppner,F.L.; Montrasio,F.; Navarro,B.; Parizek,P.; Pekarik,V.; Prinz,M.; Raeber,A.J.; Rockl,C.; Klein,M.A. - Spongiform encephalopathies: insights from transgenic models. - Advances in Virus Research 2001; 56: 313-52
AACY - Aguzzi,A.; Montrasio,F.; Kaeser,P.S. - Prions: health scare and biological challenge. - Nature Reviews. Molecular Cell Biology 2001 Feb; 2(2): 118-26
AACZ - Aguzzi,A. - Blood simple prion diagnostics - Nature Medicine 2001 Mar; 7(3): 289-90
AADA - Aguzzi,A.; Heppner,F.L. - Pathogenesis of prion diseases: a progress report. - Cell Death and Differentiation 2000 Oct; 7(10): 889-902
AADB - Aguzzi,A.; Klein,M.A.; Montrasio,F.; Pekarik,V.; Brandner,S.; Furukawa,H.; Kaser,P.; Rockl,C.; Glatzel,M. - Prions: pathogenesis and reverse genetics. - Annals of the New York Academy of Sciences 2000; 920: 140-57
AADC - Aguzzi,A. - Molecular pathology of prion diseases - Vox Sanguinis 2000; 78 Suppl 2: 25
AADD - Aguzzi,A. - Prion diseases, blood and the immune system: concerns and reality. - Haematologica 2000 Jan; 85(1): 3-10
AADE - Aguzzi,A.; Brandner,S. - The genetics of prions - a contradiction in terms? - Lancet 1999 Jul; 354 Suppl 1: SI22-5
AADF - Aguzzi,A.; Brandner,S. - Shrinking prions: new folds to old questions. - Nature Medicine 1999 May; 5(5): 486-7
AADG - Aguzzi,A.; D'Angelo,M.G.; Klein,M.A.; Frigg,R.; Fischer,M.B.; Raeber,A.J.; Rockl,C.; Musahl,C.; Hegyi,I.; Brandner,S. - [The new research frontier on prion disease] - Le nuove frontiere della ricerca sulle malattie prioniche - Pathologica 1998 Dec; 90(6): 743-52
AADI - Aguzzi,A. - Grafting mouse brains: from neurocarcinogenesis to neurodegeneration. - EMBO Journal 1998 Nov 2; 17(21): 6107-14
AADJ - Aguzzi,A. - Protein conformation dictates prion strain - Nature Medicine 1998 Oct; 4(10): 1125-6
AADH - Aguzzi,A.; Weissmann,C. - Prion diseases - Haemophilia 1998 Jul; 4(4): 619-27
AADK - Aguzzi,A.; Klein,M.A.; Musahl,C.; Raeber,A.J.; Blättler,T.; Hegyi,I.; Frigg,R.; Brandner,S. - Use of brain grafts to study the pathogenesis of prion diseases - Essays in Biochemistry 1998; 33: 133-47
AADL - Aguzzi,A.; Weissmann,C. - Spongiform encephalopathies. The prion's perplexing persistence. - Nature 1998 Apr 23; 392(6678): 763-4
APBA - Aguzzi,A.; Weissmann,C.; Blättler,T.; Raeber,A.J.; Brandner,S.; Klein,M.A. - Prions - neurotoxicity and neuroinvasion - Naunyn-Schmiedebergs Archives of Pharmacology 1998; 358(N1): SB 11-B 11
APBB - Aguzzi,A. - Fatal protein - the story of CJD, BSE and other prion diseases - Ridley,RM, Baker,HF - Nature 1998; 393(N6683): 321-2
AADM - Aguzzi,A.; Maddalena,A.; Brandner,S.; Klein,M.A. - [Molecular pathogenesis of spongiform encephalopathy] - Patogenesi molecolare delle encefalopatie spongiformi - Pathologica 1997 Oct; 89(5): 481-90
AADN - Aguzzi,A. - Prions and antiprions - Biological Chemistry 1997 Dec; 378(12): 1393-5
AADO - Aguzzi,A.; Weissmann,C. - Prion research: the next frontiers. - Nature 1997 Oct 23; 389(6653): 795-8
AADP - Aguzzi,A.; Collinge,J. - Post-exposure prophylaxis after accidental prion inoculation - Lancet 1997 Nov 22; 350(9090): 1519-20
AADQ - Aguzzi,A. - [Molecular pathogenesis of spongiform encephalopathies] - Molekulare Pathogenese der spongiformen Enzephalopathien - Verhandlungen der Deutschen Gesellschaft für Pathologie 1997; 81: 35-47
APBD - Aguzzi,A.; Bitiftler,T.; Klein,M.A.; Brandner,S.; Raeber,A.J.; Flechsig,E.; Weissmann,C. - Neurotoxicity and neuroinvasiveness of prions - Brain Pathology 1997; 7(N4): 1137-8
AADR - Aguzzi,A.; Blättler,T.; Klein,M.A.; Raeber,A.J.; Hegyi,I.; Frigg,R.; Brandner,S.; Weissmann,C. - Tracking prions: the neurografting approach. - Cellular and Molecular Life Science 1997 Jun; 53(6): 485-95
APBC - Aguzzi,A.; Barbara,J.A.J.; Brown,P.; Budka,H.; Diringer,H.; Dormont,D.; Flanagan,P.; Heeschen,W.; Hope,J.; Hörnlimann,B.; Kenney,K.; Masters,C.; Macnaughton,M.R.; Pocchiari,M.; Rohwer,R.G.; Safar,J.G.; Somogyi,A.; Tateishi,J.; Taylor,D.M.; van Duijn,C.M.; Wilesmith,J.W.; Will,R.G.; Wisher,M.H.; Asher,D.M.; de Pedro Cuesta,J.; Feek,C.; Hasebe,K.; Horaud,F.; Löwer,J.; Minor,P.D.; Nandapalan,P.; Pavlov,A.; Perez,A.C.; Ricketts,M.N.; Vicari,G.; van Aken,W.G.; Beal,R.; Menache-Aronson,D.; Bradley,R.; Bailey,A.C.; Chalumeau,H.P.; Garland,A.; Brooks,W.; Schrieber,R.; Sprengers,E.; Andjaparidze,A.G.; Bolis,C.L.; Emmanuel,J.C.; Griffiths,E.; Heymann,D.L.; Kaboyo,W.; Meslin,F.X.; Miyagawa,S.; Padilla Marroquin,A.; Schudel,A.; Zeidler,M. - Medicinal and other products and human and animal transmissible spongiform encephalopathies - memorandum from a WHO meeting - Bulletin of the World Health Organization 1997; 75(N6): 505-13
AADS - Aguzzi,A.; Raeber,A.J.; Blättler,T.; Flechsig,E.; Klein,M.A.; Weissmann,C.; Brandner,S. - Neurotoxicity and neuroinvasiveness of prions - Journal of Neurovirology 1997 May; 3 Suppl 1: S23-4
AADT - Aguzzi,A. - Neuro-immune connection in spread of prions in the body? - Lancet 1997 Mar 15; 349(9054): 742-3
AADU - Aguzzi,A.; Weissmann,C. - Spongiform encephalopathies: A suspicious signature. - Nature 1996 Oct 24; 383(6602): 666-7
AADV - Aguzzi,A. - Between cows and monkeys - Nature 1996 Jun 27; 381(6585): 734
AADW - Aguzzi,A. - Pathogenesis of spongiform encephalopathies: an update. - International Archives of Allergy and Immunology 1996 Jun; 110(2): 99-106
AADX - Aguzzi,A.; Weissmann,C. - Sleepless in Bologna: transmission of fatal familial insomnia. - Trends in Microbiology 1996 Apr; 4(4): 129-31; discussion 131-2
AADY - Aguzzi,A.; Brandner,S.; Marino,S.; Steinbach,J.P. - Transgenic and knockout mice in the study of neurodegenerative diseases - Journal of Molecular Medicine 1996 Mar; 74(3): 111-26
AADZ - Aguzzi,A.; Brandner,S.; Sure,U.; Ruedi,D.; Isenmann,S. - Transgenic and knock-out mice: models of neurological disease. - Brain Pathology 1994 Jan; 4(1): 3-20
AOPU - Arrighi,I.; Polymenidou,M.; Ross,T.M.; Aguzzi,A. - DNA vaccination strategies against prion disease - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - IV-11
AOPV - Bach,P.; Nikles,D.; Montrasio,F.; Heppner,F.L.; Aguzzi,A.; Buchholz,C.J.; Kalinke,U. - Induction of prion protein-specific antibody responses using PrP-retroparticles - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - IV-23
AXIZ - Baumann,F.; Nairz,K.; Rülicke,T.; Aguzzi,A. - In-Vivo Identification of Functional Sub-Domains within Central Domain of the Cellular Prion Protein - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.24
AXJA - Baumann,F.; Pahnke,J.; Radovanovic,I.; Bremer,J.; Rülicke,T.; Tolnay,M.; Aguzzi,A. - The Central Domain Represents an Essential Part for the Physiological Function of the Prion Protein - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.31
AVZQ - Baumann,F.; Tolnay,M.; Brabeck,C.; Pahnke,J.; Kloz,U.; Niemann,H.H.; Heikenwalder,M.; Rülicke,T.; Bürkle,A.; Aguzzi,A. - Lethal recessive myelin toxicity of prion protein lacking its central domain - EMBO Journal 2007 Jan 24; 26(2): 538-47
AWBR - Baumann,F.; Tolnay,M.; Pahnke,J.; Brabeck,C.; Niemann,H.H.; Ruelicke,T.; Bürkle,A.; Aguzzi,A. - In-vivo identification of functional domains within the cellular prion protein - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions CE-02
ABEH - Behrens,A.; Genoud,N.; Naumann,H.; Rülicke,T.; Janett,F.; Heppner,F.L.; Ledermann,B.; Aguzzi,A. - Absence of the prion protein homologue Doppel causes male sterility - EMBO Journal 2002 Jul 15; 21(14): 3652-8
ABEI - Behrens,A.; Aguzzi,A. - Small is not beautiful: antagonizing functions for the prion protein PrPc and its homologue Dpl. - Trends in Neurosciences 2002 Mar; 25(3): 150-4
ABEJ - Behrens,A.; Brandner,S.; Genoud,N.; Aguzzi,A. - Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel - EMBO Reports 2001 Apr; 2(4): 347-52
ABKD - Blättler,T.; Brandner,S.; Raeber,A.J.; Klein,M.A.; Voigtländer,T.; Weissmann,C.; Aguzzi,A. - PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain - Nature 1997 Sep 4; 389(6646): 69-73
ABPU - Brandner,S.; Klein,M.A.; Frigg,R.; Pekarik,V.; Parizek,P.; Raeber,A.J.; Glatzel,M.; Schwarz,P.; Rülicke,T.; Weissmann,C.; Aguzzi,A. - Neuroinvasion of prions: insights from mouse models. - Experimental Physiology 2000 Nov; 85(6): 705-12
ABPV - Brandner,S.; Klein,M.A.; Aguzzi,A. - [Mechanisms of neuroinvasion by prions: molecular principles and present state of research] - Mechanismen der Neuroinvasion von Prionen: molekulare Grundlagen und aktueller Stand der Forschung. - Schweizerische medizinische Wochenschrift. Journal Suisse de Medecine 2000 Mar 25; 130(12): 435-42
ABPW - Brandner,S.; Klein,M.A.; Aguzzi,A. - A crucial role for B cells in neuroinvasive scrapie - Transfusion Clinique et Biologique 1999 Feb; 6(1): 17-23
ABPX - Brandner,S.; Isenmann,S.; Kuhne,G.; Aguzzi,A. - Identification of the end stage of scrapie using infected neural grafts - Brain Pathology 1998 Jan; 8(1): 19-27
ABPY - Brandner,S.; Raeber,A.J.; Sailer,A.; Blättler,T.; Fischer,M.; Weissmann,C.; Aguzzi,A. - Normal host prion protein (PrPc) is required for scrapie spread within the central nervous system - Proceedings of the National Academy of Sciences of the United States of America 1996 Nov 12; 93(23): 13148-51
ABPZ - Brandner,S.; Isenmann,S.; Raeber,A.J.; Fischer,M.; Sailer,A.; Kobayashi,Y.; Marino,S.; Weissmann,C.; Aguzzi,A. - Normal host prion protein necessary for scrapie-induced neurotoxicity - Nature 1996 Jan 25; 379(6563): 339-43
ABZO - Budka,H.; Aguzzi,A.; Brown,P.; Brucher,J.M.; Bugiani,O.; Collinge,J.; Diringer,H.; Gullotta,F.; Haltia,M.; Hauw,J.J.; Ironside,J.W.; Kretzschmar,H.A.; Lantos,P.L.; Masullo,C.; Pocchiari,M.; Schlote,W.; Tateishi,J.; Will,R.G. - [Consensus report: tissue handling in suspected Creutzfeldt-Jakob disease and other spongiform encephalopathies (prion diseases) in the human.European Union Biomed-1 Concerted Action] - Konsensusbericht: Gewebsbehandlung bei Verdacht auf Creutzfeldt-Jakob- Krankheit und andere spongiforme Enzephalopathien (Prionen-Krankheiten) des Menschen. European Union Biomed-1 Concerted Action. - Der Pathologe 1996 Mar; 17(2): 171-5
ABZP - Budka,H.; Aguzzi,A.; Brown,P.; Brucher,J.M.; Bugiani,O.; Gullotta,F.; Haltia,M.; Hauw,J.J.; Ironside,J.W.; Jellinger,K.A.; Kretzschmar,H.A.; Lantos,P.L.; Masullo,C.; Schlote,W.; Tateishi,J.; Weller,R.O. - Neuropathological diagnostic criteria for Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases) - Brain Pathology 1995 Oct; 5(4): 459-66
ABZQ - Budka,H.; Aguzzi,A.; Brown,P.; Brucher,J.M.; Bugiani,O.; Collinge,J.; Diringer,H.; Gullotta,F.; Haltia,M.; Hauw,J.J.; Ironside,J.W.; Kretzschmar,H.A.; Lantos,P.L.; Masullo,C.; Pocchiari,M.; Schlote,W.; Tateishi,J.; Will,R.G. - Tissue handling in suspected Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases) - Brain Pathology 1995 Jul; 5(3): 319-22
ABZS - Büeler,H.; Raeber,A.J.; Sailer,A.; Fischer,M.; Aguzzi,A.; Weissmann,C. - High prion and PrPsc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene - Molecular Medicine 1994 Nov; 1(1): 19-30
ABZT - Büeler,H.; Aguzzi,A.; Sailer,A.; Greiner,R.A.; Autenried,P.; Aguet,M.; Weissmann,C. - Mice devoid of PrP are resistant to scrapie - Cell 1993 Jul 2; 73(7): 1339-47
ACNO - Chazot,G.; Broussolle,E.; Lapras,C.; Blättler,T.; Aguzzi,A.; Kopp,N. - New variant of Creutzfeldt-Jakob disease in a 26-year-old French man - Lancet 1996 Apr 27; 347(9009): 1181
AXKX - Di Guardo,G.; Marruchella,G.; Ligios,C.; Baffoni,M.; Cancedda,G.M.; Macciocu,S.; Gioia,L.; Lalatta Costerbosa,G.; Chiocchetti,R.; Clavenzani,P.; De Grossi,L.; Agrimi,U.; Aguzzi,A. - Immunohistochemistry, Immunofluorescence and Confocal Laser Microscopy: An Insight into the Enteric Nervous System During Sheep Scrapie Infection - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.133
ASTI - Donofrio,G.; Heppner,F.L.; Polymenidou,M.; Musahl,C.; Aguzzi,A. - Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies - Journal of Virology 2005 Jul; 79(13): 8330-8
AXLW - Falsig,J.; Heppner,F.L.; Julius,C.; Schwarz,P.; Aguzzi,A. - Microglia Depletion Increases Prion Replication in Organotypic Brain Slices - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.177
AEAW - Fischer,M.; Rülicke,T.; Raeber,A.J.; Sailer,A.; Moser,M.; Oesch,B.; Brandner,S.; Aguzzi,A.; Weissmann,C. - Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie - EMBO Journal 1996 Mar 15; 15(6): 1255-64
AEAX - Fischer,M.B.; Roeckl,C.; Parizek,P.; Schwarz,H.P.; Aguzzi,A. - Binding of disease-associated prion protein to plasminogen - Nature 2000 Nov 23; 408(6811): 479-83
AOSP - Flechsig,E.; Hegyi,I.; Leimeroth,R.; Zuniga,A.; Rossi,D.; Cozzio,A.; Rülicke,T.; Götz,J.; Aguzzi,A.; Weissmann,C. - Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-104
AOKC - Flechsig,E.; Hegyi,I.; Leimeroth,R.; Zuniga,A.; Rossi,D.; Cozzio,A.; Schwarz,P.; Rülicke,T.; Götz,J.; Aguzzi,A.; Weissmann,C. - Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia - EMBO Journal 2003 Jun 16; 22(12): 3095-101
AEBI - Flechsig,E.; Shmerling,D.; Hegyi,I.; Raeber,A.J.; Fischer,M.; Cozzio,A.; von Mering,C.; Aguzzi,A.; Weissmann,C. - Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice - Neuron 2000 Aug; 27(2): 399-408
AEFX - Frigg,R.; Klein,M.A.; Hegyi,I.; Zinkernagel,R.M.; Aguzzi,A. - Scrapie pathogenesis in subclinically infected B-cell-deficient mice - Journal of Virology 1999 Nov; 73(11): 9584-8
ATTI - Galvan,C.; Camoletto,P.G.; Dotti,C.G.; Aguzzi,A.; Ledesma,M.D. - Proper axonal distribution of PrPc depends on cholesterol-sphingomyelin-enriched membrane domains and is developmentally regulated in hippocampal neurons - Molecular and Cellular Neurosciences 2005 Nov; 30(3): 304-15
ASWT - Gavin,R.; Braun,N.; Nicolas,O.; Parra,B.; Urena,J.M.; Mingorance,A.; Soriano,E.; Torres,J.M.; Aguzzi,A.; del Rio,J.A. - PrP(106-126) activates neuronal intracellular kinases and Egr1 synthesis through activation of NADPH-oxidase independently of PrPc - FEBS Letters 2005 Aug 1; 579(19): 4099-106
AQJO - Genoud,N.; Behrens,A.; Miele,G.; Robay,D.; Heppner,F.L.; Freigang,S.; Aguzzi,A. - Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions - Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 23; 101(12): 4198-203
AQJP - Genoud,N.; Behrens,A.; Arrighi,I.; Aguzzi,A. - Prion proteins and infertility: insight from mouse models. - Cytogenetic and Genome Research 2003; 103(3-4): 285-9
ASOZ - Glatzel,M.; Mohajeri,M.H.; Poirier,R.; Nitsch,R.M.; Schwarz,P.; Lu,B.; Aguzzi,A. - No influence of amyloid-beta-degrading neprilysin activity on prion pathogenesis - Journal of General Virology 2005 Jun; 86(6): 1861-7
ASJR - Glatzel,M.; Stoeck,K.; Seeger,H.; Lührs,T.; Aguzzi,A. - Human prion diseases: molecular and clinical aspects. - Archives of Neurology 2005 Apr; 62(4): 545-52
ARHF - Glatzel,M.; Giger,O.; Braun,N.; Aguzzi,A. - The peripheral nervous system and the pathogenesis of prion diseases - Current Molecular Medicine 2004 Jun; 4(4): 355-9
AQJT - Glatzel,M.; Giger,O.; Seeger,H.; Aguzzi,A. - Variant Creutzfeldt-Jakob disease: between lymphoid organs and brain. - Trends in Microbiology 2004 Feb; 12(2): 51-3
APHL - Glatzel,M.; Ott,P.M.; Linder,T.; Gebbers,J.O.; Gmur,A.; Wust,W.; Huber,G.; Moch,H.; Podvinec,M.; Stamm,B.; Aguzzi,A. - Human prion diseases: epidemiology and integrated risk assessment. - Lancet Neurology 2003 Dec; 2(12): 757-63
APHM - Glatzel,M.; Abela,E.; Maissen,M.; Aguzzi,A. - Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease - The New England Journal of Medicine 2003 Nov 6; 349(19): 1812-20
AOTE - Glatzel,M.; Abela,E.; Maissen,M.; Aguzzi,A. - Extraneural pathological prion protein in sporadic Creutzfeldt-Jakob disease - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - DG-24
ANML - Glatzel,M.; Gottwein,J.; Aguzzi,A. - [Prions as the driving force in transmissible spongiform encephalopathies] - Prionen als Motor der transmissiblen spongiformen Enzephalopathien - Schweizer Archiv für Tierheilkunde 2002 Dec; 144(12): 633-8
AEPP - Glatzel,M.; Pekarik,V.; Lührs,T.; Dittami,J.; Aguzzi,A. - Analysis of the prion protein in primates reveals a new polymorphism in codon 226 (Y226F) - Biological Chemistry 2002 Jun; 383(6): 1021-5
AEPQ - Glatzel,M.; Rogivue,C.; Ghani,A.C.; Streffer,J.R.; Amsler,L.; Aguzzi,A. - Incidence of Creutzfeldt-Jakob disease in Switzerland - Lancet 2002 Jul 13; 360(9327): 139-41
AEPR - Glatzel,M.; Brandner,S.; Klein,M.A.; Horstmann,S.; Aguzzi,A. - Prions - Role of the peripheral nervous system - Virus Research 2002 Jan 30; 82(1-2): 53
AEPS - Glatzel,M.; Aguzzi,A. - The shifting biology of prions - Brain Research. Brain Research Reviews 2001 Oct; 36(2-3): 241-8
AOAE - Glatzel,M.; Aguzzi,A. - Sympathetic prions - TheScientificWorldJournal [electronic resource] 2001 Oct 13; 1: 555-6
AEPT - Glatzel,M.; Heppner,F.L.; Albers,K.M.; Aguzzi,A. - Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion - Neuron 2001 Jul 19; 31(1): 25-34
AEPU - Glatzel,M.; Aguzzi,A. - PrPc expression in the peripheral nervous system is a determinant of prion neuroinvasion - Journal of General Virology 2000 Nov; 81(11): 2813-21
AEPV - Glatzel,M.; Aguzzi,A. - Peripheral pathogenesis of prion diseases - Microbes and Infection 2000 May; 2(6): 613-9
AEPW - Glatzel,M.; Klein,M.A.; Brandner,S.; Aguzzi,A. - Prions: from neurografts to neuroinvasion. - Archives of Virology. Supplementum 2000(16): 3-12
AXOC - Haybaeck,J.; Heikenwalder,M.; Margalith,I.; Zeller,N.; Bridel,C.; Schwarz,P.; Merz,K.; Stitz,L.; Aguzzi,A. - Intranasal and Aerosolic Prion Transmission - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.103
AWGM - Haybaeck,J.; Heikenwalder,M.; Margalith,I.; Zeller,N.; Bridell,C.; Schwarz,P.; Merz,K.; Gaguli,E.; Stitz,L.; Aguzzi,A. - Intranasal and aerosolic prion transmission - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PA-21
AXOF - Heikenwälder,M.; Margalith,I.; Julius,C.; Polymenidou,M.; Haybäck,J.; Marcel,A.; Schwarz,P.; Kurrer,M.; Aguzzi,A. - Granulomas Induce Prion Replication Competence Independent of Follicular Dendritic Cells - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Oral Abstracts FC3.5
AXOG - Heikenwälder,M.; Margalith,I.; Haybäck,J.; Bänziger,S.; Hutter,G.; Nairz,K.; Heppner,F.; Sigurdson,C.; Speck,R.; Aguzzi,A. - Replication of Human Prions in a "Humanized" Mouse Model System - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.104
AWGP - Heikenwalder,M.; Margalith,I.; Zeller,N.; Haybaeck,J.; Kurrer,M.; Aguzzi,A. - Granulomatous inflammation induces prion accumulation and replication - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PA-22
AWGQ - Heikenwalder,M.; Federau,C.; von Boehmer,L.; Zeller,N.; Schwarz,P.; Becher,B.; Aguzzi,A. - Germinal center B-cells are dispensable for peripheral prion replication and neuroinvasion - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PA-23
ARLK - Heikenwalder,M.; Zeller,N.; Seeger,H.; Prinz,M.; Klöhn,P.C.; Schwarz,P.; Ruddle,N.H.; Weissmann,C.; Aguzzi,A. - Chronic lymphocytic inflammation specifies the organ tropism of prions - Science 2005 Feb 18; 307(5712): 1107-10
AQKL - Heikenwalder,M.; Prinz,M.; Heppner,F.L.; Aguzzi,A. - Current concepts and controversies in prion immunopathology - Journal of Molecular Neuroscience 2004; 23(1-2): 3-12
ARQE - Heppner,F.L.; Aguzzi,A. - Recent developments in prion immunotherapy - Current Opinion in Immunology 2004 Oct; 16(5): 594-8
AFHW - Heppner,F.L.; Aguzzi,A. - [Immunity against prions?] - Immunität gegen Prionen? - Deutsche medizinische Wochenschrift 2002 Feb 15; 127(7): 328-30
AFHX - Heppner,F.L.; Arrighi,I.; Kalinke,U.; Aguzzi,A. - Immunity against prions? - Trends in Molecular Medicine 2001 Nov; 7(11): 477-9
AFHY - Heppner,F.L.; Musahl,C.; Arrighi,I.; Klein,M.A.; Rülicke,T.; Oesch,B.; Zinkernagel,R.M.; Kalinke,U.; Aguzzi,A. - Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies - Science 2001 Oct 5; 294(5540): 178-82
AFHZ - Heppner,F.L.; Christ,A.D.; Klein,M.A.; Prinz,M.; Fried,M.; Kraehenbuhl,J.P.; Aguzzi,A. - Transepithelial prion transport by M cells - Nature Medicine 2001 Sep; 7(9): 976-7
AFIA - Heppner,F.L.; Prinz,M.; Aguzzi,A. - Pathogenesis of prion diseases: possible implications of microglial cells. - Progress in Brain Research 2001; 132: 737-50
ARHQ - Hugel,B.; Martinez,M.C.; Kunzelmann,C.; Blättler,T.; Aguzzi,A.; Freyssinet,J.M. - Modulation of signal transduction through the cellular prion protein is linked to its incorporation in lipid rafts - Cellular and Molecular Life Science 2004 Dec; 61(23): 2998-3007
APIH - Hutter,G.; Heppner,F.L.; Aguzzi,A. - No superoxide dismutase activity of cellular prion protein in vivo - Biological Chemistry 2003 Sep; 384(9): 1279-85
AFVW - Isenmann,S.; Brandner,S.; Aguzzi,A. - Neuroectodermal grafting: a new tool for the study of neurodegenerative diseases. - Histology and Histopathology 1996 Oct; 11(4): 1063-73
AXPM - Julius,C.; Yusa,S.; Parkyn,C.; Mootoosamy,R.; Morris,R.; Campenot,B.; Glatzel,M.; Miele,G.; Aguzzi,A. - Neuronal Propagation of Prions - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.78
AWHR - Julius,C.; Heikenwalder,M.; Pasparakis,M.; Prinz,M.; Schwarz,P.; Aguzzi,A. - The role of brain specific NF-kB activation in prion disease - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PA-29
AGDD - Kaeser,P.S.; Klein,M.A.; Schwarz,P.; Aguzzi,A. - Efficient lymphoreticular prion propagation requires PrPc in stromal and hematopoietic cells - Journal of Virology 2001 Aug; 75(15): 7097-106
AGOG - Klein,M.A.; Kaeser,P.S.; Schwarz,P.; Weyd,H.; Xenarios,I.; Zinkernagel,R.M.; Carroll,M.C.; Verbeek,J.S.; Botto,M.; Walport,M.J.; Molina,H.; Kalinke,U.; Acha-Orbea,H.; Aguzzi,A. - Complement facilitates early prion pathogenesis - Nature Medicine 2001 Apr; 7(4): 488-92
AGOH - Klein,M.A.; Aguzzi,A. - The Neuroimmune Interface in Prion Diseases - News in Physiological Sciences : an International Journal of Physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 2000 Oct; 15: 250-255
AGOI - Klein,M.A.; Frigg,R.; Raeber,A.J.; Flechsig,E.; Hegyi,I.; Zinkernagel,R.M.; Weissmann,C.; Aguzzi,A. - PrP expression in B lymphocytes is not required for prion neuroinvasion - Nature Medicine 1998 Dec; 4(12): 1429-33
AGOJ - Klein,M.A.; Frigg,R.; Flechsig,E.; Raeber,A.J.; Kalinke,U.; Bluethmann,H.; Bootz,F.; Suter,M.; Zinkernagel,R.M.; Aguzzi,A. - A crucial role for B cells in neuroinvasive scrapie - Nature 1997 Dec 18-25; 390(6661): 687-90
AUBF - Kovacs,G.G.; Puopolo,M.; Ladogana,A.; Pocchiari,M.; Budka,H.; van Duijn,C.M.; Collins,S.J.; Boyd,A.; Giulivi,A.; Coulthart,M.B.; Delasnerie-Laupretre,N.; Brandel,J.P.; Zerr,I.; Kretzschmar,H.A.; de Pedro Cuesta,J.; Calero-Lara,M.; Glatzel,M.; Aguzzi,A.; Bishop,M.T.; Knight,R.S.G.; Belay,G.; Will,R.; Mitrova,E. - EUROCJD. - Genetic prion disease: the EUROCJD experience. - Human Genetics 2005 Nov; 118(2): 166-74
APUX - Kovacs,G.G.; Lindeck-Pozza,E.; Chimelli,L.; Araujo,A.Q.; Gabbai,A.A.; Ströbel,T.; Glatzel,M.; Aguzzi,A.; Budka,H. - Creutzfeldt-Jakob disease and inclusion body myositis: Abundant disease-associated prion protein in muscle. - Annals of Neurology 2004 Jan; 55(1): 121-5
AXQI - Kranich,J.; Zabel,M.D.; Heikenwalder,M.; Arrighi,I.; Schwarz,P.; Prinz,M.; von Teichman,A.; Haas,K.M.; Zeller,N.; Tedder,T.F.; Weis,J.H.; Aguzzi,A. - CD21/35 - A Peripheral Prion Receptor? - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.64
AWIH - Kranich,J.; Schwarz,P.; Miele,G.; Julius,C.; Heppner,F.; Pedersen,J.; Aguzzi,A. - The role of MFG-E8 in prion pathogenesis - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Oral sessions ORAL-38
ATIL - Kranich,J.; Miele,G.; Seeger,H.; Aguzzi,A. - Transcriptional and proteomic consequences of inhibition of prion protein expression in neuroblastoma cells - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Cell Biology of PrPc and PrPsc CELL-43
AXQK - Krautler,N.J.; Calella,A.M.; Rutishauser,D.; Baumann,F.; Polymenidou,M.; Aguzzi,A. - The Prion Protein Interactome during Health and Disease - A Proteomic Analysis - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.19
AGWZ - Künzi,V.; Glatzel,M.; Nakano,M.Y.; Greber,U.F.; van Leuven,F.; Aguzzi,A. - Unhampered prion neuroinvasion despite impaired fast axonal transport in transgenic mice overexpressing four-repeat tau - Journal of Neuroscience 2002 Sep 1; 22(17): 7471-7
ATVU - Ladogana,A.; Puopolo,M.; Croes,E.A.; Budka,H.; Jarius,C.; Collins,S.J.; Klug,G.M.; Sutcliffe,T.; Giulivi,A.; Alperovitch,A.; Delasnerie-Laupretre,N.; Brandel,J.P.; Poser,S.; Kretzschmar,H.A.; Rietveld,I.; Mitrova,E.; de Pedro Cuesta,J.; Martinez-Martin,P.; Glatzel,M.; Aguzzi,A.; Knight,R.S.G.; Ward,H.J.T.; Pocchiari,M.; van Duijn,C.M.; Will,R.G.; Zerr,I. - Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada - Neurology 2005 May 10; 64(9): 1586-91
AUNX - Landolt,H.P.; Glatzel,M.; Blättler,T.; Achermann,P.; Roth,C.; Mathis,J.; Weis,J.; Tobler,I.; Aguzzi,A.; Bassetti,C.L. - Sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease - Neurology 2006 May 9; 66(9): 1418-24
AWJB - Ligios,C.; Sigurdson,C.; Carta,A.; Carcassola,G.; Cancedda,M.G.; Madau,L.; Uras,P.; Galistu,A.; Santucciu,C.; Maestrale,C.; Crudeli,S.; Attene,S.; Aguzzi,A. - PrPsc deposits in lungs and mammary glands of sheep experimentally coinfected with scrapie and maedi-visna virus - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PA-32
ATDN - Ligios,C.; Sigurdson,C.J.; Santucciu,C.; Carcassola,G.; Manco,G.; Basagni,M.; Maestrale,C.; Cancedda,M.G.; Madau,L.; Aguzzi,A. - PrPsc in mammary glands of sheep affected by scrapie and mastitis - Nature Medicine 2005 Nov; 11(11): 1137-8
AOWE - Maissen,M.; Aguzzi,A. - Inhibition of Protease-Resistant Prion Protein Accumulation in Scrapie-Infected Neuroblastoma Cells by Serum Deprivation - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-106
AHSN - Maissen,M.; Roeckl,C.; Glatzel,M.; Goldmann,W.; Aguzzi,A. - Plasminogen binds to disease-associated prion protein of multiple species - Lancet 2001 Jun 23; 357(9273): 2026-8
AYHR - Marruchella,G.; Ligios,C.; Albanese,V.; Cancedda,M.G.; Madau,L.; Lalatta-Costerbosa,G.; Mazzoni,M.; Clavenzani,P.; Chiocchetti,R.; Sarli,G.; De Grossi,L.; Agrimi,U.; Aguzzi,A.; Di Guardo,G. - Enteroglial and neuronal involvement without apparent neuron loss in ileal enteric nervous system plexuses from scrapie-affected sheep - Journal of General Virology 2007 Oct; 88(10): 2899-904
AWJR - Marruchella,G.; Ligios,C.; Uras,P.; Zucca,R.; Lalatta-Costerbosa,G.; Chiocchetti,R.; Clavenzani,P.; Mazzoni,M.; Albanese,V.; D'Agostino,C.; Borroni,R.; Vaccari,G.; De Grossi,L.; Rosone,F.; Aguzzi,A.; Di Guardo,G. - Natural and oral experimental scrapie infection in Sarda breed sheep: a comparative pathogenic study on ileal enteric nervous system plexuses - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PA-35
ARNJ - Masel,J.; Genoud,N.; Aguzzi,A. - Efficient inhibition of prion replication by PrP-Fc(2) suggests that the prion is a PrPsc oligomer - Journal of Molecular Biology 2005 Feb 4; 345(5): 1243-51
ANRZ - Meier,P.; Genoud,N.; Prinz,M.; Maissen,M.; Rülicke,T.; Zurbriggen,A.; Raeber,A.J.; Aguzzi,A. - Soluble Dimeric Prion Protein Binds PrPsc In Vivo and Antagonizes Prion Disease - Cell 2003 Apr 4; 113(1): 49-60
AOWU - Mertz,K.D.; Brunner,E.; Moos,R.; Aguzzi,A. - Isolation of Macromolecular Complexes of PrP and Cofactors Using the Tandem Affinity Purification (TAP) Method - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-19
ATJT - Miele,G.; Seeger,H.; Eberhard,R.; Marino,D.; Heikenwälder,M.; Hock,C.; Glatzel,M.; Aguzzi,A. - Secreted preclinical biomarkers of prion infection - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Diagnosis DIA-05
AINL - Montrasio,F.; Cozzio,A.; Flechsig,E.; Rossi,D.; Klein,M.A.; Rülicke,T.; Raeber,A.J.; Vosshenrich,C.A.; Proft,J.; Aguzzi,A.; Weissmann,C. - B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice - Proceedings of the National Academy of Sciences of the United States of America 2001 Mar 27; 98(7): 4034-7
AINM - Montrasio,F.; Frigg,R.; Glatzel,M.; Klein,M.A.; Mackay,F.; Aguzzi,A.; Weissmann,C. - Impaired prion replication in spleens of mice lacking functional follicular dendritic cells - Science 2000 May 19; 288(5469): 1257-9
AXTL - Kav,N.; Shi,Y.; Polymenidou,M.; Aguzzi,A.; Yajima,W. - Properties of an Anti-mouse Prion Protein-specific Single-chain Antibody - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Protein Misfolding P01.68
ASKU - Nikles,D.; Bach,P.; Boller,K.; Merten,C.A.; Montrasio,F.; Heppner,F.L.; Aguzzi,A.; Cichutek,K.; Kalinke,U.; Buchholz,C.J. - Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP. - Journal of Virology 2005 Apr; 79(7): 4033-42
AXTP - Nilsson,K.P.R.; Sigurdson,C.J.; Fransson,S.; Manco,G.; Hammarström,P.; Aguzzi,A. - Luminescent Conjugated Polymers - Conformation Sensitive Optical Probes for Staining and Characterization of Prion Strains - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Natural and Experimental Strains P02.19
AWKZ - Nilsson,K.P.R.; Sigurdson,C.J.; Aguzzi,A. - Conjugated polyelectrolytes - conformation sensitive optical probes for staining and characterization of prion strains - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PR-25
AXTY - Nicolas,O.; Gavin,R.; Braun, N.; Urena,J.; Fontana,X.; Soriano,E.; Aguzzi,A.; Del Rio,J.A. - Bcl-2 Overexpression Rescues Cerebellar Degeneration in Prion-Deficient Mice that Overexpress Amino-Terminally Truncated Prion - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.76
ASVW - Papassotiropoulos,A.; Wollmer,M.A.; Aguzzi,A.; Hock,C.; Nitsch,R.M.; de Quervain,D.J. - The prion gene is associated with human long-term memory - Human Molecular Genetics 2005 Aug 1; 14(15): 2241-6
AJFE - Parizek,P.; Roeckl,C.; Weber,J.; Flechsig,E.; Aguzzi,A.; Raeber,A.J. - Similar turnover and shedding of the cellular prion protein in primary lymphoid and neuronal cells - The Journal of Biological Chemistry 2001 Nov 30; 276(48): 44627-32
AQYH - Pocchiari,M.; Puopolo,M.; Croes,E.A.; Budka,H.; Gelpi,E.; Collins,S.J.; Lewis,V.; Sutcliffe,T.; Guilivi,A.; Delasnerie-Laupretre,N.; Brandel,J.P.; Alperovitch,A.; Zerr,I.; Poser,S.; Kretzschmar,H.A.; Ladogana,A.; Rietvald,I.; Mitrova,E.; Martinez-Martin,P.; de Pedro Cuesta,J.; Glatzel,M.; Aguzzi,A.; Cooper,S.A.; Mackenzie,J.; van Duijn,C.M.; Will,R.G. - Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies - Brain: A Journal of Neurology 2004 Oct; 127(10): 2348-59
AJND - Politopoulou,G.; Seebach,J.D.; Schmugge,M.; Schwarz,H.P.; Aguzzi,A. - Age-related expression of the cellular prion protein in human peripheral blood leukocytes - Haematologica 2000 Jun; 85(6): 580-7
ATXI - Polymenidou,M.; Stoeck,K.; Glatzel,M.; Vey,M.; Bellon,A.; Aguzzi,A. - Coexistence of multiple PrPsc types in individuals with Creutzfeldt-Jakob disease - Lancet Neurology 2005 Dec; 4(12): 805-14
ARJI - Polymenidou,M.; Heppner,F.L.; Pellicioli,E.C.; Urich,E.; Miele,G.; Braun,N.; Wopfner,F.; Schätzl,H.M.; Becher,B.; Aguzzi,A. - Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection - Proceedings of the National Academy of Sciences of the United States of America 2004 Oct 5; 101 Suppl 2: 14670-6
AODE - Praus,M.; Kettelgerdes,G.; Baier,M.; Holzhutter,H.G.; Jungblut,P.R.; Maissen,M.; Epple,G.; Schleuning,W.D.; Kottgen,E.; Aguzzi,A.; Gessner,R. - Stimulation of plasminogen activation by recombinant cellular prion protein is conserved in the NH2-terminal fragment PrP23-110 - Thrombosis and Haemostasis 2003 May; 89(5): 812-9
AVNY - Priller,J.; Prinz,M.; Heikenwalder,M.; Zeller,N.; Schwarz,P.; Heppner,F.L.; Aguzzi,A. - Early and rapid engraftment of bone marrow-derived microglia in scrapie - Journal of Neuroscience 2006 Nov 8; 26(45): 11753-62
ARJL - Prinz,M.; Montrasio,F.; Furukawa,H.; van der Haar,M.E.; Schwarz,P.; Rülicke,T.; Giger,O.T.; Hausler,K.G.; Perez,D.; Glatzel,M.; Aguzzi,A. - Intrinsic resistance of oligodendrocytes to prion infection - Journal of Neuroscience 2004 Jun 30; 24(26): 5974-81
APLA - Prinz,M.; Heikenwalder,M.; Junt,T.; Schwarz,P.; Glatzel,M.; Heppner,F.L.; Fu,Y.X.; Lipp,M.; Aguzzi,A. - Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion - Nature 2003 Oct 30; 425(6961): 957-62
ANSG - Prinz,M.; Huber,G.; Macpherson,A.J.; Heppner,F.L.; Glatzel,M.; Eugster,H.P.; Wagner,N.; Aguzzi,A. - Oral Prion Infection Requires Normal Numbers of Peyer's Patches but Not of Enteric Lymphocytes - American Journal of Pathology 2003 Apr; 162(4): 1103-11
ANNC - Prinz,M.; Heikenwalder,M.; Schwarz,P.; Takeda,K.; Akira,S.; Aguzzi,A. - Prion pathogenesis in the absence of Toll-like receptor signalling - EMBO Reports 2003 Feb; 4(2): 195-9
AJPF - Prinz,M.; Montrasio,F.; Klein,M.A.; Schwarz,P.; Priller,J.; Odermatt,B.; Pfeffer,K.; Aguzzi,A. - Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells - Proceedings of the National Academy of Sciences of the United States of America 2002 Jan 22; 99(2): 919-24
AUDQ - Radovanovic,I.; Braun,N.; Giger,O.T.; Mertz,K.; Miele,G.; Prinz,M.; Navarro,B.; Aguzzi,A. - Truncated prion protein and Doppel are myelinotoxic in the absence of oligodendrocytic PrPc - Journal of Neuroscience 2005 May 11; 25(19): 4879-88
AJVC - Raeber,A.J.; Montrasio,F.; Hegyi,I.; Frigg,R.; Klein,M.A.; Aguzzi,A.; Weissmann,C. - Studies on prion replication in spleen - Developmental Immunology 2001; 8(3-4): 291-304
AJVD - Raeber,A.J.; Aguzzi,A. - Engulfment of prions in the germinal centre - Immunology Today 2000 Feb; 21(2): 66-7
AJVE - Raeber,A.J.; Klein,M.A.; Frigg,R.; Flechsig,E.; Aguzzi,A.; Weissmann,C. - PrP-dependent association of prions with splenic but not circulating lymphocytes of scrapie-infected mice - EMBO Journal 1999 May 17; 18(10): 2702-6
AJVF - Raeber,A.J.; Sailer,A.; Hegyi,I.; Klein,M.A.; Rülicke,T.; Fischer,M.; Brandner,S.; Aguzzi,A.; Weissmann,C. - Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication - Proceedings of the National Academy of Sciences of the United States of America 1999 Mar 30; 96(7): 3987-92
AJVG - Raeber,A.J.; Brandner,S.; Klein,M.A.; Benninger,Y.; Musahl,C.; Frigg,R.; Roeckl,C.; Fischer,M.B.; Weissmann,C.; Aguzzi,A. - Transgenic and knockout mice in research on prion diseases - Brain Pathology 1998 Oct; 8(4): 715-33
AJVH - Raeber,A.J.; Klein,M.A.; Frigg,R.; Brandner,S.; Blättler,T.; Aguzzi,A. - [Significance of prion protein in transmission of prions and in pathogenesis of spongiform encephalopathies] - Die Bedeutung des Prion-Proteins in der Ausbreitung von Prionen und in der Pathogenese der spongiformen Enzephalopathien - Wiener Medizinische Wochenschrift 1998; 148(4): 74-7
AJVI - Raeber,A.J.; Race,R.E.; Brandner,S.; Priola,S.A.; Sailer,A.; Bessen,R.A.; Mucke,L.; Manson,J.; Aguzzi,A.; Oldstone,M.B.A.; Weissmann,C.; Chesebro,B. - Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie - EMBO Journal 1997 Oct 15; 16(20): 6057-65
AXUY - Rangel,A.H.; Burgaya,F.; Gavin,R.; Soriano,E.; Aguzzi,A.; Del Rio,J.A. - Enhanced Susceptibility of Prnp-Deficient Mice to Kainate-Induced Seizures, Neuronal Apoptosis, and Death: Role of AMPA/Kainate Receptors - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Natural and Experimental Strains P02.28
ANNR - Rogivue,C.; Gottwein,J.; Aguzzi,A.; Glatzel,M. - [Transmissible spongiform encephalopathies in humans] - Transmissible spongiforme Enzephalopathien beim Menschen - Schweizer Archiv für Tierheilkunde 2002 Dec; 144(12): 685-90
AQOE - Rossetti,A.O.; Bogousslavsky,J.; Glatzel,M.; Aguzzi,A. - Mimicry of variant Creutzfeldt-Jakob disease by sporadic Creutzfeldt-Jakob disease: importance of the pulvinar sign. - Archives of Neurology 2004 Mar; 61(3): 445-6
ANZB - Rossetti,A.O.; Glatzel,M.; Aguzzi,A.; Janzer,R.; Bogousslavsky,J. - Clinical and radiological mimicry of vCJD in a valine homozygous PrPsc type 1 sCJD patient - Journal of Neurology. Zeitschrift für Neurologie 2003 Apr; 250(4): 491-3
AKEH - Rossi,D.; Cozzio,A.; Flechsig,E.; Klein,M.A.; Rülicke,T.; Aguzzi,A.; Weissmann,C. - Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain - EMBO Journal 2001 Feb 15; 20(4): 694-702
ATUO - Russmann,H.; Vingerhoets,F.; Miklossy,J.; Maeder,P.; Glatzel,M.; Aguzzi,A.; Bogousslavsky,J. - Sporadic Creutzfeldt-Jakob disease: a comparison of pathological findings and diffusion weighted imaging. - Journal of Neurology. Zeitschrift für Neurologie 2005 Mar; 252(3): 338-42
AWMT - Rutishauser,D.; Calella,A.M.; Polymenidou,M.; Moss,R.; Mertz,K.; Aguzzi,A. - Proteomic analysis of the prion protein in vivo - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions CE-43
AKIA - Sailer,A.; Büeler,H.; Fischer,M.; Aguzzi,A.; Weissmann,C. - No propagation of prions in mice devoid of PrP - Cell 1994 Jul 1; 77(7): 967-8
AKNW - Schnyder,H.; Aguzzi,A. - [Creutzfeldt-Jakob disease] - Die Creutzfeldt-Jakob-Erkrankung - Schweizerische medizinische Wochenschrift. Journal Suisse de Medecine 1995 Apr 22; 125(16): 802-9
ATSB - Schoch,G.; Seeger,H.; Bogousslavsky,J.; Tolnay,M.; Janzer,R.C.; Aguzzi,A.; Glatzel,M. - Analysis of prion strains by PrPsc profiling in sporadic Creutzfeldt-Jakob disease - PLoS Medicine 2006 Feb; 3(2): e14
ATQB - Seeger,H.; Heikenwälder,M.; Zeller,N.; Kranich,J.; Schwarz,P.; Gaspert,A.; Seifert,B.; Aguzzi,A. - Chronic kidney inflammation induces urinary prion excretion in scrapie-infected mice - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Pathogenesis PATH-38
ATED - Seeger,H.; Heikenwalder,M.; Zeller,N.; Kranich,J.; Schwarz,P.; Gaspert,A.; Seifert,B.; Miele,G.; Aguzzi,A. - Coincident scrapie infection and nephritis lead to urinary prion excretion - Science 2005 Oct 14; 310(5746): 324-6
AKVB - Shmerling,D.; Hegyi,I.; Fischer,M.; Blättler,T.; Brandner,S.; Götz,J.; Rülicke,T.; Flechsig,E.; Cozzio,A.; von Mering,C.; Hangartner,C.; Aguzzi,A.; Weissmann,C. - Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions - Cell 1998 Apr 17; 93(2): 203-14
AYDW - Sigurdson,C.J.; Aguzzi,A. - Chronic wasting disease - Biochimica et Biophysica Acta - Molecular Basis of Disease 2007 Jun; 1772(6): 610-8
AWNP - Sigurdson,C.J.; Heikenwälder,M.; Manco,G.; Hornemann,S.; Nilsson,P.; Liberski,P.; Ott,D.; Rülicke,T.; Pahnke,J.; Baumann,F.; Miele,G.; Stitz,L.; Schwarz,P.; Wüthrich,K.; Aguzzi,A. - Elk-like prion protein triggers spontaneous spongiform encephalopathy with florid plaques in mice - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions S-21
AVHS - Sigurdson,C.J.; Manco,G.; Schwarz,P.; Liberski,P.; Hoover,E.A.; Hornemann,S.; Polymenidou,M.; Miller,M.W.; Glatzel,M.; Aguzzi,A. - Strain fidelity of chronic wasting disease upon murine adaptation - Journal of Virology 2006 Dec; 80(24): 12303-11
ATRO - Sigurdson,C.J.; Heikenwälder,M.; Manco,G.; Hornemann,S.; Liberski,P.; Pahnke,J.; Baumann,F.; Miele,G.; Wüthrich,K.; Aguzzi,A. - Spongiform encephalopathy and prion plaque generation by mouse transgenesis - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Structure of PrP and molecular determinants of infectivity STRCT-30
ARTJ - Sigurdson,C.J.; Glatzel,M.; Aguzzi,A. - Comment on "Failure to detect prion protein (PrPres) by immunohistochemistry in striated muscle tissues of animals experimentally inoculated with agents of transmissible spongiform encephalopathy" - Veterinary Pathology 2005 Jan; 42(1): 107
AVGN - Sigurdson,C.J.; Polymenidou,M.; Aguzzi,A. - Reconstructing prions: fibril assembly from simple yeast to complex mammals. - Neuro-degenerative Diseases 2005; 2(1): 1-5
AKXL - Siso,S.; Puig,B.; Varea,R.; Vidal,E.; Acin,C.; Prinz,M.; Montrasio,F.; Badiola,J.J.; Aguzzi,A.; Pumarola,M.; Ferrer,I. - Abnormal synaptic protein expression and cell death in murine scrapie - Acta Neuropathologica 2002 Jun; 103(6): 615-26
AXXC - Steele,A.; Jackson,W.; Hutter,G.; Aguzzi,A.; King,O.; Raymond,G.; Caughey,B.; Lindquist,S. - A Critical Role for Heat Shock Factor 1 in Prion Pathogenesis - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Oral Abstracts FC4.8
ARTO - Steinacker,P.; Schwarz,P.; Reim,K.; Brechlin,P.; Jahn,O.; Kratzin,H.; Aitken,A.; Wiltfang,J.; Aguzzi,A.; Bahn,E.; Baxter,H.C.; Brose,N.; Otto,M. - Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein - Molecular and Cellular Biology 2005 Feb; 25(4): 1339-46
AOZJ - Steinacker,P.; Schwarz,P.; Aguzzi,A.; Aitken,A.; Brose,N.; Otto,M. - Unchanged survival curves of 14-3-3 gamma knock-out mice after inoculation with pathological prion protein - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - PG-25
ALDK - Steinbach,J.P.; Aguzzi,A. - XVI Winter meeting of the Swiss Society of Neuropathology, St Moritz, 20-23 March 1996 - Neuropathology and Applied Neurobiology 1996 Jun; 22(3): 261-3
ATLO - Stoeck,K.; Blättler,T.; Amsler,L.; Seeger,H.; Glatzel,M.; Aguzzi,A. - Clinical and pathological spectrum of CJD in Switzerland - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Diagnosis DIA-52
ALQG - Thackray,A.M.; Klein,M.A.; Aguzzi,A.; Bujdoso,R. - Chronic subclinical prion disease induced by low-dose inoculum - Journal of Virology 2002 Mar; 76(5): 2510-7
ARUA - Uelhoff,A.; Tatzelt,J.; Aguzzi,A.; Winklhofer,K.F.; Haass,C. - A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein - The Journal of Biological Chemistry 2005 Feb 18; 280(7): 5137-40
AMAZ - Vingerhoets,F.J.; Hegyi,I.; Aguzzi,A.; Myers,P.; Pizzolato,G.; Landis,T. - An unusual case of Creutzfeldt-Jakob disease - Neurology 1998 Aug; 51(2): 617-9
AUSH - Vogelgesang,S.; Glatzel,M.; Walker,L.C.; Kroemer,H.K.; Aguzzi,A.; Warzok,R.W. - Cerebrovascular P-glycoprotein expression is decreased in Creutzfeldt-Jakob disease - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Poster: Pathogenese/Infektion PATH-08
AVTY - Vogelgesang,S.; Glatzel,M.; Walker,L.C.; Kroemer,H.K.; Aguzzi,A.; Warzok,R.W. - Cerebrovascular P-glycoprotein expression is decreased in Creutzfeldt-Jakob disease - Acta Neuropathologica 2006 May; 111(5): 436-43
AMHC - Weber,T.; Aguzzi,A. - The spectrum of transmissible spongiform encephalopathies - Intervirology 1997; 40(2-3): 198-212
ASRV - Weissmann,C.; Aguzzi,A. - Approaches to therapy of prion diseases - Annual Review of Medicine 2005; 56: 321-44
AMIB - Weissmann,C.; Raeber,A.J.; Montrasio,F.; Hegyi,I.; Frigg,R.; Klein,M.A.; Aguzzi,A. - Prions and the lymphoreticular system - Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 2001 Feb 28; 356(1406): 177-84
AMIC - Weissmann,C.; Aguzzi,A. - Perspectives: neurobiology. PrP's double causes trouble. - Science 1999 Oct 29; 286(5441): 914-5
AMIE - Weissmann,C.; Fischer,M.; Raeber,A.J.; Büeler,H.; Sailer,A.; Shmerling,D.; Rülicke,T.; Brandner,S.; Aguzzi,A. - The use of transgenic mice in the investigation of transmissible spongiform encephalopathies - Revue Scientifique et Technique de l'Office International des Epizooties 1998 Apr; 17(1): 278-90
AMIF - Weissmann,C.; Aguzzi,A. - Bovine spongiform encephalopathy and early onset variant Creutzfeldt-Jakob disease - Current Opinion in Neurobiology 1997 Oct; 7(5): 695-700
AMIG - Weissmann,C.; Fischer,M.; Raeber,A.J.; Büeler,H.; Sailer,A.; Shmerling,D.; Rülicke,T.; Brandner,S.; Aguzzi,A. - The use of transgenic mice in the investigation of transmissible spongiform encephalopathies - International Journal of Experimental Pathology 1996 Dec; 77(6): 283-93
AMIJ - Weissmann,C.; Fischer,M.; Raeber,A.J.; Büeler,H.; Sailer,A.; Shmerling,D.; Rülicke,T.; Brandner,S.; Aguzzi,A. - The role of PrP in pathogenesis of experimental scrapie - Cold Spring Harbor Symposia on Quantitative Biology 1996; 61: 511-22
AMIM - Weissmann,C.; Büeler,H.; Fischer,M.; Sailer,A.; Aguzzi,A.; Aguet,M. - PrP-deficient mice are resistant to scrapie - Slow Infections of the Central Nervous System (Ed. Bjornsson, J.; Carp, R.I.; Love, A.; Wisniewski, H.M.) 1994 Jun 6; 724: 235-40
AMIP - Weissmann,C.; Büeler,H.; Sailer,A.; Fischer,M.; Aguet,M.; Aguzzi,A. - Role of PrP in prion diseases - British Medical Bulletin 1993 Oct; 49(4): 995-1011
AMXU - Zanusso,G.; Liu,D.; Ferrari,S.; Hegyi,I.; Yin,X.; Aguzzi,A.; Hornemann,S.; Liemann,S.; Glockshuber,R.; Manson,J.C.; Brown,P.; Petersen,R.B.; Gambetti,P.; Sy,M.S. - Prion protein expression in different species: analysis with a panel of new mAbs. - Proceedings of the National Academy of Sciences of the United States of America 1998 Jul 21; 95(15): 8812-6